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Vacuolar Protein Sorting 54 Homolog (S. Cerevisiae) (VPS54) ELISA Kits

VPS54 encodes for a protein that in yeast forms part of a trimeric vacuolar-protein-sorting complex that is required for retrograde transport of proteins from prevacuoles to the late Golgi compartment. Additionally we are shipping Vacuolar Protein Sorting 54 Homolog (S. Cerevisiae) Antibodies (35) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse VPS54 VPS54 245944 Q5SPW0
Anti-Human VPS54 VPS54 51542 Q9P1Q0
Anti-Rat VPS54 VPS54 286932 Q9JMK8
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More ELISA Kits for Vacuolar Protein Sorting 54 Homolog (S. Cerevisiae) Interaction Partners

Mouse (Murine) Vacuolar Protein Sorting 54 Homolog (S. Cerevisiae) (VPS54) interaction partners

  1. This study demonstrated that the cerebellum is affected by neurodegenerative and inflammatory processes in the Wobbler mouse model of ALS.

  2. Investigation of cells derived from wobbler and Vps54 null mutant embryos demonstrates impaired retrograde transport of the Cholera-toxin B subunit to the trans-Golgi network and mis (show AMH ELISA Kits)-sorting of mannose-6-phosphate receptors and cargo proteins.

  3. We conclude that a missense mutation in VPS54, an essential component of the Golgi-associated retrograde protein complex, not only prevents the formation of an acrosome but also initiates a cascade of metabolic abnormalities and a stress reaction.

  4. Severely reduced levels of mutant Vps54 and, consequently, of the whole GARP complex underlie the phenotype of the wobbler mouse.

  5. Mutation of Vps54 causes motor neuron disease and defective spermiogenesis in the wobbler mouse

Human Vacuolar Protein Sorting 54 Homolog (S. Cerevisiae) (VPS54) interaction partners

  1. This study suggests that VPS54 mutations are not a common cause of Amyotrophic Lateral Sclerosis in Italian population

  2. Golgi-associated retrograde protein orchestrates retrograde transport from endosomes to the trans-Golgi network by promoting vesicle tethering and assembly of SNARE (show NAPA ELISA Kits) complexes in consecutive, independent steps.[Golgi associated retrograde protein]

  3. Severely reduced levels of mutant Vps54 and, consequently, of the whole GARP complex underlie the phenotype of the wobbler mouse.

  4. Golgi associated retrograde protein complex, consisting of the Vps52 (show VPS52 ELISA Kits), Vps53 (show VPS53 ELISA Kits), and Vps54 proteins, shows significant conservation between various species but diversification and specialization result in important differences in human cells.

  5. Missorting of cathepsin D in GARP-depleted cells results from accumulation of recycling MPRs in a population of light, small vesicles downstream of endosomes.

  6. mutations in VPS54 are not a major cause of ALS (amyotrophic lateral sclerosis)

  7. PMID:12039048 mostly pertains to mouse and rat but contains some general comments about the structure and function of Vps54 homolog in other species, including human.

Vacuolar Protein Sorting 54 Homolog (S. Cerevisiae) (VPS54) Antigen Profile

Antigen Summary

This gene encodes for a protein that in yeast forms part of a trimeric vacuolar-protein-sorting complex that is required for retrograde transport of proteins from prevacuoles to the late Golgi compartment. As in yeast, mammalian Vps54 proteins contain a coiled-coil region and dileucine motifs. Alternative splicing results in multiple transcript variants encoding different isoforms

Gene names and symbols associated with VPS54

  • Protein VPS-54 (vps-54) antibody
  • vacuolar protein sorting 54 (yeast) (Vps54) antibody
  • vacuolar protein sorting 54 homolog (S. cerevisiae) (VPS54) antibody
  • vacuolar protein sorting 54 homolog (S. cerevisiae) (Vps54) antibody
  • 5330404P15Rik antibody
  • HCC8 antibody
  • hVps54L antibody
  • mSLP8 antibody
  • SLP-8p antibody
  • VPS54L antibody
  • Vsp54 antibody
  • WR antibody

Protein level used designations for VPS54

tumor antigen SLP-8p homolog , vacuolar protein sorting-associated protein 54 , hepatocellular carcinoma protein 8 , tumor antigen HOM-HCC-8 , tumor antigen SLP-8p , vps54-like protein

GENE ID SPECIES
179473 Caenorhabditis elegans
245944 Mus musculus
421280 Gallus gallus
51542 Homo sapiens
474616 Canis lupus familiaris
783762 Bos taurus
286932 Rattus norvegicus
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