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anti-Vang-Like 2 (Van Gogh, Drosophila) (VANGL2) Antibodies

The protein encoded by VANGL2 is a membrane protein involved in the regulation of planar cell polarity, especially in the stereociliary bundles of the cochlea. Additionally we are shipping VANGL2 Proteins (4) and VANGL2 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
VANGL2 93840 Q91ZD4
VANGL2 57216 Q9ULK5
VANGL2 289229 P84889
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Top anti-VANGL2 Antibodies at antibodies-online.com

Showing 10 out of 73 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN190866 (0.3 ug/ml) staining of Mouse Brain lysate (35 ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Mouse Rabbit Un-conjugated WB VANGL2 Antibody (N-term) (ABIN1881989) western blot analysis in mouse brain tissue lysates (35 µg/lane). This demonstrates the VANGL2 antibody detected the VANGL2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human lung carcinoma labeled with Rabbit Anti VANGL2 Polyclonal Antibody, Unconjugated (ABIN1385778) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$595.83
Details
Human Goat Un-conjugated ELISA, WB Western Blot: VANGL2 Antibody [ABIN252943] - ABIN252943 (0.3ug/ml) staining of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 5 to 7 Days
$427.88
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

VANGL2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-VANGL2 Antibodies

  1. Mouse (Murine) Polyclonal VANGL2 Primary Antibody for WB - ABIN1881989 : Devenport, Fuchs: Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles. in Nature cell biology 2008 (PubMed)
    Show all 5 references for ABIN1881989

  2. Human Polyclonal VANGL2 Primary Antibody for ELISA, WB - ABIN190866 : Kibar, Vogan, Groulx, Justice, Underhill, Gros: Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail. in Nature genetics 2001 (PubMed)

More Antibodies against VANGL2 Interaction Partners

Mouse (Murine) Vang-Like 2 (Van Gogh, Drosophila) (VANGL2) interaction partners

  1. a new and essential role for Vangl2-dependent planar cell polarity signaling in the intraretinal path-finding of retinal ganglion cell axons

  2. Vangl2-regulated polarisation and subsequent acquisition of an epithelial phenotype is essential to lengthen the tubular outflow vessel, a process that is essential for on-going cardiac morphogenesis (show XIRP1 Antibodies).

  3. Vangl2 regulates E-cadherin (show CDH1 Antibodies) in epithelial cells.

  4. Vangl2 function in podocytes is important for glomerular development and protects against glomerular injury in adult animals.

  5. Vangl1 (show Vangl1 Antibodies) and Vangl2 may play a key role in the embryo implantation of mice

  6. The first signal, controlled by cadherin, EGF (show EGF Antibodies)-like, laminin G-like, seven-pass, G-type receptor (Celsr) 2 (show CELSR2 Antibodies), Celsr3 (show CELSR3 Antibodies), Frizzled3 (Fzd3 (show FZD3 Antibodies)) and Van Gogh like2 (Vangl2) organizes multicilia in individual cells (single-cell polarity)

  7. Celsr2 (show CELSR2 Antibodies)-3 and Fzd3 (show FZD3 Antibodies) regulate axonal navigation in the forebrain by using mechanisms different from classical epithelial core planar cell polarity, and require interacting partners other than Vangl1 (show Vangl1 Antibodies)-2 that remain to be identified.

  8. Testin (show TES Antibodies) interacts with vangl2 genetically to regulate inner ear sensory cell orientation and the normal development of the female reproductive tract in mice.

  9. Apical boundary rearrangement is inhibited in Vangl2 mutant neural epithelium.

  10. Morphological and histological examination of homozygous mouse embryos revealed a neural tube closure defect that leads to craniorachischis ...Vangl2(m1Yzcm) may be a loss-of-function mutant.

Zebrafish Vang-Like 2 (Van Gogh, Drosophila) (VANGL2) interaction partners

  1. dynamic Vangl2 intracellular distribution is coordinated with and necessary for the changes in convergence and extension cell behaviors during gastrulation

  2. we found that the critical period for Vangl2 function coincides with the initial stages of FBM neuron migration out of rhombomere 4.

  3. Vangl2 regulates FBM neuron migration by acting in floor plate cells, independently of cilia function

  4. VANGL2 regulates the endocytosis and cell-surface availability of MMP14 in a manner that is dependent on focal adhesion kinase.

  5. Vangl2(R259L) behaved like the wild-type allele in overexpression and morpholino knockdown/rescue assays in zebrafish embryos.

  6. Rack1 (show GNB2L1 Antibodies) has a dominant-negative effect on Vangl2 localization and gastrulation.

  7. data suggest that bbs8 (show TTC8 Antibodies) and vangl2 act synergistically on cell polarization to establish and maintain the appropriate length and number of cilia in the Kupffer's vesicle and thereby facilitate correct LR asymmetry

  8. Vangl2 is required for asymmetric localization and posterior tilting of primary motile cilia at the apical membrane of epithelial cells.

  9. show that anterior hindbrain (r2/r3) motor neuron migration appears to be independent of vangl2 and pk1b functions, and suggest that multiple mechanisms regulate motor neuron migration along the anterior-posterior axis of the zebrafish hindbrain

  10. The vangl2 gene product mediates cellular interactions that confer directionality on distinct movements during vertebrate embryogenesis.

Human Vang-Like 2 (Van Gogh, Drosophila) (VANGL2) interaction partners

  1. VANGL2 is overexpressed in basal breast cancers. It is involved in the proliferative signal cascade of the VANGL2-SQSTM1 (show SQSTM1 Antibodies)-JNK (show MAPK8 Antibodies) pathway.

  2. Propose that Arfrp1 (show ARFRP1 Antibodies) exposes a binding site on AP-1 (show FOSB Antibodies) that recognizes the Vangl2 sorting motif for capture into a transport vesicle destined for the proximal surface of a polarized epithelial cell.

  3. The aberrant VANGL2 promoter methylation and the decreased gene expression is associated with Tetralogy of Fallot.

  4. Asymmetry of VANGL2 in migrating lymphocytes as a tool to monitor activity of the mammalian WNT (show WNT2 Antibodies)/planar cell polarity pathway.

  5. Van-Gogh-like 2 is frequently methylated in MSI (show MSI1 Antibodies)-CRCs with BRAF (show BRAF Antibodies) mutation and may act as a tumour suppressor gene, counteracting WNT (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling.

  6. these findings strongly implicate VANGL2 in the genetic causation of spinal NTDs in a subset of patients and provide additional evidence for a pathogenic role of PCP (show PRCP Antibodies) signaling in these malformations.

  7. Loss of membrane targeting of Vangl1 (show Vangl1 Antibodies) and Vangl2 proteins causes neural tube defects.

  8. The planar cell polarity genes Celsr1 (show CELSR1 Antibodies) and Vangl2 are required for normal lung branching morphogenesis.

  9. Van Gogh-Like 2 regulates tumor cell migration and matrix metalloproteinase (show MMP20 Antibodies)-dependent invasion.

  10. Results suggest that there is no specific mutation responsible for the Tetralogy of Fallot phenotype in the Vangl2 gene [Vangl2].

VANGL2 Antigen Profile

Protein Summary

The protein encoded by this gene is a membrane protein involved in the regulation of planar cell polarity, especially in the stereociliary bundles of the cochlea. The encoded protein transmits directional signals to individual cells or groups of cells in epithelial sheets. This protein is also involved in the development of the neural plate.

Gene names and symbols associated with VANGL2

  • vang-like 2 (van gogh, Drosophila) (VANGL2) antibody
  • VANGL planar cell polarity protein 2 (vangl2) antibody
  • vang-like 2 (LOC100354291) antibody
  • vang-like 2 (van gogh, Drosophila) (Vangl2) antibody
  • vang-like 2 (van gogh, Drosophila) (vangl2) antibody
  • VANGL planar cell polarity protein 2 (VANGL2) antibody
  • VANGL planar cell polarity protein 2 (Vangl2) antibody
  • C530001F03Rik antibody
  • loop-tail antibody
  • Lp antibody
  • LPP1 antibody
  • LTAP antibody
  • ska17 antibody
  • ska antibody
  • STB1 antibody
  • STBM antibody
  • STBM1 antibody
  • strabismus antibody
  • tri antibody
  • vang antibody
  • Vang1l2 antibody
  • VANGL2 antibody

Protein level used designations for VANGL2

vang-like 2 (van gogh, Drosophila) , Van Gogh , protein strabismus , van Gogh-like protein 2 , vang-like protein 2 , vang-like 2 , loop tail associated protein , loop-tail protein 1 , loop-tail-associated protein , vang (van gogh)-like 2 , protein trilobite , strabismus , trilobite , loop-tail protein 1 homolog , strabismus 1

GENE ID SPECIES
610037 Canis lupus familiaris
426903 Gallus gallus
613073 Xenopus (Silurana) tropicalis
720239 Macaca mulatta
100354291 Oryctolagus cuniculus
93840 Mus musculus
245949 Danio rerio
520544 Bos taurus
57216 Homo sapiens
289229 Rattus norvegicus
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