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Vanin 1 Proteins (VNN1)

VNN1 encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. Additionally we are shipping Vanin 1 Antibodies (52) and Vanin 1 Kits (17) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
VNN1 22361 Q9Z0K8
VNN1 8876 O95497
Rat VNN1 VNN1 29142  
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Top Vanin 1 Proteins at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Human Cells Human His tag 50 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 16 Days
$382.80
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$3,309.17
Details
Yeast Dog His tag   1 mg Log in to see 56 to 66 Days
$3,325.67
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,325.67
Details
HOST_HEK293 Human His tag   50 μg Log in to see 5 Days
$385.00
Details
HOST_Escherichia coli (E. coli) Human His tag   100 μg Log in to see 11 to 13 Days
$668.80
Details
HOST_Escherichia coli (E. coli) Mouse His tag   100 μg Log in to see 11 to 13 Days
$704.00
Details

VNN1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , , , ,
,

Top referenced Vanin 1 Proteins

  1. Human VNN1 Protein expressed in Wheat germ - ABIN1325026 : Dammanahalli, Stevens, Terkeltaub: Vanin-1 pantetheinase drives smooth muscle cell activation in post-arterial injury neointimal hyperplasia. in PLoS ONE 2012 (PubMed)

More Proteins for Vanin 1 (VNN1) Interaction Partners

Mouse (Murine) Vanin 1 (VNN1) interaction partners

  1. serum pantetheinas, encoded by the VNN1 gene, level regulates erythrocyte life span and modulates the risk of developing complicated malaria.

  2. Results suggest an important role for VNN1 in regulating hepatic gluconeogenesis.

  3. Data indicate that genetic ablation of the Vanin-1 (Vnn1) gene in SF-1 (NR5A1 (show NR5A1 Proteins)) transgenic mice significantly reduced the severity of neoplastic lesions in the adrenal cortex.

  4. Microparticle internalization required the interaction of the ectoenzyme Vanin-1 (VNN1), an abundant surface protein on the microparticles, with lipid raft domains of endothelial cells.

  5. Epithelial vanin-1 controls inflammation-driven carcinogenesis in the colitis-associated colon cancer model.

  6. Data show that Vanin-1(-/-) mice better controlled inflammatory reaction and intestinal injury in either acute (NSAID administration) or chronic (Schistosoma infection) inflammation.

  7. Data show that Vanin-1(-/-) mice, which lack cysteamine in tissues, exhibit resistance to oxidative injury induced by whole-body gamma-irradiation or paraquat.

  8. steroidogenic factor-1 (show NR5A1 Proteins) is able to bind to two sites in the Vanin-1 promoter, whereas SOX9 (show SOX9 Proteins) can bind to a single interposed site defined by DNA footprinting

  9. Data suggest that Vanin-1 is an epithelial sensor of stress that exerts a dominant control over innate immune responses in tissue, and the Vanin-1/pantetheinase activity might be a new target for therapeutic intervention in inflammatory bowel disease.

  10. Vanin-1 is necessary for the formation of granulomas during host response to Coxiella burnetti but does not change bacterial clearance in vivo.

Human Vanin 1 (VNN1) interaction partners

  1. serum pantetheinas, encoded by the VNN1 gene, level regulates erythrocyte life span and modulates the risk of developing complicated malaria.

  2. VNN1 contributes to corticosteroid responsiveness, and changes in VNN1 nasal epithelial mRNA expression and VNN1 promoter methylation might be clinically useful biomarkers of treatment response in asthmatic children.

  3. Our study provides strong biological evidence for the association of the identified SNP with BP and suggests that vanin-1 misfolding and degradation are the underlying molecular mechanism.

  4. show that hepatic vanin-1 is under extremely sensitive regulation by PPARalpha (show PPARA Proteins) and that plasma vanin activity could serve as a readout of changes in PPARalpha (show PPARA Proteins) activity in human subjects

  5. The X-ray crystal structure of human vanin 1 at 2.25 A resolution is presented, which is the first reported structure from the vanin family, as well as a crystal structure of vanin 1 bound to a specific inhibitor.

  6. Serum vanin-1 levels may be low in the end-stage renal failure and transiently increase after transplant owing to transient renal function deterioration, which does not lead to elevation of serum creatinine levels in renal transplant patients.

  7. Our results suggest that vanin-1 can distinguish between chronic responders and non-responders ITP (show ITPA Proteins) patients as well as between newly diagnosed ITP (show ITPA Proteins) patients and healthy controls.

  8. Alternative Splicing in VNN1 gene is associated with colorectal cancer.

  9. Single-nucleotide polymorphisms in the Regulatory Regions of the VNN1 Gene Are Associated with inflammatory bowel diseases.

  10. Microparticle internalization required the interaction of the ectoenzyme Vanin-1 (VNN1), an abundant surface protein on the microparticles, with lipid raft domains of endothelial cells.

Vanin 1 (VNN1) Protein Profile

Protein Summary

This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24.

Gene names and symbols associated with Vanin 1 Proteins (VNN1)

  • vanin 1 (VNN1)
  • vanin 1 (vnn1)
  • vanin 1 (LOC100217969)
  • vascular non-inflammatory molecule 2-like (VNN2)
  • vanin 1 (Vnn1)
  • HDLCQ8 protein
  • Tiff66 protein
  • V-1 protein
  • vanin-1 protein
  • vnn1.1 protein

Protein level used designations for Vanin 1 Proteins (VNN1)

vanin 1 , vanin 1, gene 1 , pantetheinase , pantetheine hydrolase , vanin-1 , vascular non-inflammatory molecule 1 , vannin 1 , TIFF66

GENE ID SPECIES
421701 Gallus gallus
496642 Xenopus (Silurana) tropicalis
100217969 Taeniopygia guttata
100220807 Taeniopygia guttata
22361 Mus musculus
8876 Homo sapiens
526704 Bos taurus
442973 Canis lupus familiaris
397246 Sus scrofa
29142 Rattus norvegicus
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