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VIPR1 encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Additionally we are shipping Vasoactive Intestinal Peptide Receptor 1 Kits (15) and Vasoactive Intestinal Peptide Receptor 1 Proteins (6) and many more products for this protein.
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Human Polyclonal VIPR1 Primary Antibody for WB - ABIN1881994
Mlakar, Strazisar, Sok, Glavac: Oligonucleotide DNA microarray profiling of lung adenocarcinoma revealed significant downregulation and deletions of vasoactive intestinal peptide receptor 1. in Cancer investigation 2010
Show all 2 Pubmed References
Human Polyclonal VIPR1 Primary Antibody for ICC, IF - ABIN4365551
Bertolini, Pretzlaff, Sulk, Bähr, Gherardini, Uchida, Reibelt, Kinori, Rossi, Bíró, Paus: Vasoactive intestinal peptide, whose receptor-mediated signalling may be defective in alopecia areata, provides protection from hair follicle immune privilege collapse. in The British journal of dermatology 2016
Human Polyclonal VIPR1 Primary Antibody for IHC (p) - ABIN4365549
Berger, Vistisen, Barrett, Hazlett: Effects of VIP on corneal reconstitution and homeostasis following Pseudomonas aeruginosa induced keratitis. in Investigative ophthalmology & visual science 2012
In vitro-polarized macrophages by GM-CSF (show CSF2 Antibodies) (GM-MO), with a proinflammatory profile, expressed higher levels of VIP (show Vip Antibodies) receptors, vasoactive intestinal polypeptide (show Vip Antibodies) receptors 1 and 2 (VPAC1 and VPAC2 (show VIPR2 Antibodies), respectively), than macrophages polarized by M-CSF (show CSF1 Antibodies) (M-MO) with anti-inflammatory activities. RA synovial macrophages, according to their GM-CSF (show CSF2 Antibodies)-like polarization state, expressed both VPAC1 and VPAC2 (show VIPR2 Antibodies).
VPAC1 rs9677 CC genotype could be correlated with a reduced response to statin therapy and seems to be involved in diabetes cardiomyopathy in female patients with type 2 diabetes.
The results reveal that more severe inflammation, based on high levels of IL-6 (show IL6 Antibodies), is associated with lower expression of VPAC1 and, conversely, with increased expression of VPAC2 (show VIPR2 Antibodies).
variations at the 3'UTR (show UTS2R Antibodies) of the VPAC-1 gene act synergistically to affect the expression of the luciferase as well as of the GFP reporter genes expressed in HEK293T cells.
These data suggest that VPAC1 overexpression is associated with poorer differentiation of colon cancer, which is likely caused by subsequent EGFR (show EGFR Antibodies) activation in cancer cells.
VIP (show Vip Antibodies) regulates CFTR (show CFTR Antibodies) membrane expression and function in Calu (show CALU Antibodies)-3 cells by increasing its interaction with NHERF1 (show SLC9A3R1 Antibodies) and P-ERM (show ETV5 Antibodies) in a VPAC1- and PKCepsilon (show PRKCE Antibodies)-dependent manner.
VPAC1 receptor has a role in endotoxemia in peripheral blood mononuclear cells
The overexpression of VPAC1 and VPAC2 (show VIPR2 Antibodies) receptors and COX-2 (show COX2 Antibodies) in cancer tissue gives them a potential role as targets for diagnosis of prostate cancer.
hree residues play an important role in VPAC1 interaction with the first histidine residue of VIP (show Vip Antibodies). These data demonstrate that VIP (show Vip Antibodies) and PG97-269 bind to distinct domains of VPAC1
The genetic association reported here indicates that VIP (show Vip Antibodies)/VPAC1 signaling can be a relevant pathway in the pathogenesis of type 2 diabetes in females
This study demonstrated that VPAC1 receptor (Vipr1)-deficient mice exhibit ameliorated experimental autoimmune encephalomyelitis, with specific deficits in the effector stage.
VPAC1R mRNA expression was significantly decreased 3 days after ischemia induced by bilateral common carotid artery occlusion
Cyclophosphamide-induced cystitis decreased VPAC1 receptor transcript expression in the urothelium of WT (4 h, 48 h, & chronic) & NGF-OE mice.
Data support the notion that both VPAC1 and VPAC2 (show VIPR2 Antibodies) receptors are dynamically regulated by Ikaros (show IKZF1 Antibodies), a master transcriptional regulator for thymocyte differentiation, during early thymic development.
results support that decline in VIP (show Vip Antibodies)/VPAC local levels may influence survival/apoptosis intracellular set point in NOD acinar cells and their clearance, contributing to gland homeostasis loss in a model of Sjogren's syndrome
Homozygous deletion of VPAC1 resulted in fetal, neonatal, and postweaning death owing to failure to thrive, intestinal obstruction, and hypoglycemia.
VIP (show Vip Antibodies) enhancement of the severity of dextran sodium sulfate-induced colitis is mediated solely by VPAC1 receptors in mice.
Data describe PACAP, vasoactive intestinal polypeptide, and PAC1, VPAC1, VPAC2 transcripts or protein expression in urothelium and detrusor smooth muscle and lumbosacral dorsal root ganglia in NGF-overexpressing and wildtype mice.
VPAC(1)-R activation aggravates atherosclerotic lesion formation in apolipoprotein E (show APOE Antibodies)-deficient mice through enhanced inflammatory activity in the vessel wall.
VIP (show Vip Antibodies) and its receptors (VPAC1, VPAC2 (show VIPR2 Antibodies)) were identified in type II taste cells of the taste bud, and VIP (show Vip Antibodies) knockout mice exhibit enhanced taste preference to sweet tastants.
Implanting vascular bundles into the tissue engineered bone can significantly improve the expression levels of NK1R (show TACR1 Antibodies) and VIPR1.
The study confirmed the presence of VPAC1 receptor in the tissues of the porcine female reproductive tract what clearly shows the possibility of influence of vasoactive intestinal polypeptide (show Vip Antibodies) on the porcine ovary, oviduct and uterus.
This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. Several transcript variants encoding different isoforms have been found for this gene.
PACAP type II receptor
, VIP and PACAP receptor 1
, VIP receptor, type I
, pituitary adenylate cyclase activating polypeptide receptor, type II
, vasoactive intestinal polypeptide receptor 1
, VIP receptor subtype 1
, pituitary adenylate cyclase-activating polypeptide type II receptor
, Vasopressive intestinal peptide receptor
, vasoactive intestinal peptide receptor 1
, vasoactive intestinal polypeptide receptor 1-like
, vasoactive intestinal peptide/pituitary adenylate cyclase activating polypeptide receptor 1
, vpac1 receptor
, vasoactive intestinal polypeptide receptor type 1
, VIP receptor
, Vasoactive intestinal polypeptide receptor