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Ventral Anterior Homeobox 1 Proteins (VAX1)

VAX1 encodes a homeo-domain containing protein from a class of homeobox transcription factors which are conserved in vertebrates. Additionally we are shipping VAX1 Antibodies (32) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
VAX1 11023 Q5SQQ9
VAX1 64571 Q9JM00
Mouse VAX1 VAX1 22326 Q2NKI2
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Top VAX1 Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,781.17
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,849.00
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,880.17
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,907.67
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

VAX1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

More Proteins for Ventral Anterior Homeobox 1 (VAX1) Interaction Partners

Human Ventral Anterior Homeobox 1 (VAX1) interaction partners

  1. Our study replicated previous GWAS findings for markers in VAX1 in the Asian population, and identified rare variants in PAX7 (show PAX7 Proteins) and VAX1 that may contribute to the etiology of CL(P).

  2. VAX1 rs10787760, rs6585429 and rs1871345 polymorphisms may be involved in nonsyndromic cleft lip with or without cleft palate in Brazilian patients, but there is no association with polymorphisms in FGF12 (show FGF12 Proteins), VCL (show VCL Proteins), or CX43 (show GJA1 Proteins)

  3. The data do not support the hypothesis that highly penetrant rare variants in VAX1 are a cause of nonsyndromic cleft lip with or without cleft palate.

  4. This is the first description of a patient with a VAX1 mutation and establishes VAX1 as a new causative gene for anophthalmia/microphthalmia (A/M) in humans.

Zebrafish Ventral Anterior Homeobox 1 (VAX1) interaction partners

  1. vax1 and vax2 (show VAX2 Proteins) are expressed in overlapping domains encompassing the ventral retina, optic stalks and preoptic area; Hh signals act downstream of the Nodal pathway to promote Vax gene expression.

Mouse (Murine) Ventral Anterior Homeobox 1 (VAX1) interaction partners

  1. In this study, we investigate the mechanism by which VAX1 controls fertility finding that VAX1 is required for maintenance of Gnrh1 gene expression and deletion of Vax1 from GnRH neurons leads to complete infertility.

  2. Vax1 possesses a novel retinal ganglion cell axon growth factor activity.

  3. Vax1 Heterozygous subfertility originates in the hypothalamus by disrupting the hypothalamic-pituitary-gonadal axis. In addition, male subfertility may also be due to an unknown effect of Vax1 in the testis.

  4. Vax1 and Vax2 (show VAX2 Proteins) genes counteract Mitf (show MITF Proteins)-induced respecification of the retinal pigment epithelium.

  5. the absence of Vax1 causes the rostral oral ectoderm to form an ectopic fold that eventually develops into a separate second pituitary with all the pituitary cell types and neuronal fibers characteristic of the normal pituitary

  6. Vax1 has a role in basal ganglia subventricular zone development

  7. These data indicate that Vax1 is a potent regulator of subventricular zone organization and neural stem cell proliferation, with important consequences on postnatal neurogenesis.

VAX1 Protein Profile

Protein Summary

This gene encodes a homeo-domain containing protein from a class of homeobox transcription factors which are conserved in vertebrates. Genes of this family are involved in the regulation of body development and morphogenesis. The most conserved genes, called HOX genes are found in special gene clusters. This gene belongs to the VAX subfamily and lies in the vicinity of the EMX homeobox gene family. Another member of VAX family is located on chromosome 2. The encoded protein may play an important role in the development of anterior ventral forebrain and visual system. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with VAX1

  • ventral anterior homeobox 1 (LOC100231129)
  • ventral anterior homeobox 1 (VAX1)
  • ventral anterior homeobox 1 (Vax1)
  • ventral anterior homeobox 1 (vax1)
  • ventral anterior homeobox 1 (vax1-a)
  • ventral anterior homeobox containing gene 1 (Vax1)
  • MCOPS11 protein
  • vax protein
  • Vax1 protein
  • vax1b protein
  • vax1b-a protein
  • xvax1 protein
  • xvax1b protein

Protein level used designations for VAX1

ventral anterior homeobox containing gene 1 , homeobox protein , ventral anterior homeobox 1a , Vax , ventral anterior homeobox 1

GENE ID SPECIES
100231129 Taeniopygia guttata
11023 Homo sapiens
486906 Canis lupus familiaris
782056 Bos taurus
64571 Rattus norvegicus
373870 Danio rerio
373698 Xenopus laevis
395582 Gallus gallus
22326 Mus musculus
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