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VAX2 encodes a homeobox protein and is almost exclusively expressed in the ventral portion of the retina during development. Additionally we are shipping VAX2 Antibodies (40) and many more products for this protein.
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A susceptibility locus was identified with lead single nucleotide polymorphism rs3771395 on chromosome 2p13.3 (meta-analysis, P = 1.97 x 10(-7)) in the VAX2 gene for astigmatism.
vax1 (show VAX1 Proteins) and vax2 are expressed in overlapping domains encompassing the ventral retina, optic stalks and preoptic area; Hh signals act downstream of the Nodal pathway to promote Vax (show VAX1 Proteins) gene expression.
Vax1 (show VAX1 Proteins) and Vax2 genes counteract Mitf (show MITF Proteins)-induced respecification of the retinal pigment epithelium.
Vax2 is both necessary and sufficient for the control of intraretinal retinoic acid metabolism, which in turn contributes to the appropriate expression of cone opsins in the vertebrate eye.
This gene encodes a homeobox protein and is almost exclusively expressed in the ventral portion of the retina during development. In mouse studies, this gene was found to be required for the correct formation of the optic fissure and other aspects of retinal development.
ventral anterior homeobox 2
, ventral anterior homeobox 2b
, ventral anterior homeobox 3
, ventral anterior homeobox containing gene 2
, ventral retina homeodomain protein