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Versican Proteins (Vcan)

Vcan is a member of the aggrecan/versican proteoglycan family. Additionally we are shipping Versican Antibodies (101) and Versican Kits (42) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Vcan 1462 P13611
Vcan 13003  
Rat Vcan Vcan 114122 Q9ERB4
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Top Versican Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$704.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$788.70
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$246.96
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$889.07
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$967.75
Details

Vcan Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Versican (Vcan) Interaction Partners

Zebrafish Versican (Vcan) interaction partners

  1. The isolation and characterization of a cDNA encoding zebrafish dermacan, a novel member of hyaluronan (HA)-binding proteoglycans, which was termed after its characteristic expression in the zebrafish dermal bones.

Human Versican (Vcan) interaction partners

  1. Versican localizes to the nucleus in proliferating mesenchymal cells and suggest role in mitotic spindle organization during cell division.

  2. VCAN and VEGF (show VEGFA Proteins) were associated with survival in CRC (show CALR Proteins) patients with PM after CRS (show CARS Proteins) and HIPEC

  3. Versican is a novel modulator of hepatic fibrosis.

  4. versican mRNA is up-regulated much more highly (>600 fold) by long term hypoxia (5 days) than by 1 day of hypoxia.

  5. Versican V1 overexpression induces a myofibroblast-like phenotype in cultured fibroblasts.

  6. Versican upregulation in Sezary cells alters growth, motility and resistance to chemotherapy.

  7. Versican isoform V1 is associated with high-grade gliomas.

  8. Significant elevation of VCAN and its associated molecules imply their role in multiple myeloma

  9. Our results suggest that TGF-beta1 (show TGFB1 Proteins) up-regulates versican expression by suppressing miR (show MLXIP Proteins)-143, and this pathway is important for osteosarcoma cell migration and invasion.

  10. Circulating monocytes may contribute to the fibrotic process in a subset of systemic sclerosis patients by amplifying a positive feedback loop consisting of versican, CCL2 (show CCL2 Proteins), and the influx of monocytes

Mouse (Murine) Versican (Vcan) interaction partners

  1. Versican localizes to the nucleus in proliferating mesenchymal cells and suggest role in mitotic spindle organization during cell division.

  2. Pelvic irradiation increases versican expression in bladder and rectum.

  3. Versican V1 overexpression induces a myofibroblast-like phenotype in cultured fibroblasts.

  4. The data suggest that versican plays an important role in fundamental, overlapping cellular processes in lung development and infection.

  5. Our results show that versican released from glioma promotes tumor expansion through glioma-associated microglial/macrophage TLR2 signaling and subsequent expression of MT1-MMP (show MMP14 Proteins).

  6. Arylsulfatase B (show ARSB Proteins) regulates versican expression by galectin-3 (show LGALS3 Proteins) and AP-1 (show JUN Proteins) mediated transcriptional effects.

  7. Versican regulates the growth of leiomyosarcoma tumors.

  8. expression of Vcan mRNA splice form proteins alters heart morphology and cellular protein profiles

  9. These findings suggest that versican and hyaluronan synthesis may play an important role in the innate immune response to gram-negative lung infection.

  10. Versican 3'-untranslated region (3'UTR) promotes dermal wound repair and fibroblast migration by regulating miRNA activity.

Cow (Bovine) Versican (Vcan) interaction partners

  1. Data show that expression of mRNAs for aggrecan (show ACAN Proteins), collagen type II, and versican were significantly effected by the intervention.

  2. Data show that biglycan (show BGN Proteins), collagen type I, collagen type II, decorin (show DCN Proteins), and versican were significantly affected by vibration duration, frequency, and amplitude.

Pig (Porcine) Versican (Vcan) interaction partners

  1. The relationship between hyaluronan synthesis and levels of versican, fibronectin (show FN1 Proteins) and several other extracellular matrix components in trabecular meshwork cells from the anterior segment of the eye was investigated.

Versican (Vcan) Protein Profile

Protein Summary

This gene is a member of the aggrecan/versican proteoglycan family. The protein encoded is a large chondroitin sulfate proteoglycan and is a major component of the extracellular matrix. This protein is involved in cell adhesion, proliferation, proliferation, migration and angiogenesis and plays a central role in tissue morphogenesis and maintenance. Mutations in this gene are the cause of Wagner syndrome type 1. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Versican Proteins (Vcan)

  • versican a (vcana)
  • versican b (vcanb)
  • versican (VCAN)
  • versican (vcan)
  • versican (Vcan)
  • versican (LOC100008666)
  • 5430420N07Rik protein
  • 9430051N09 protein
  • br146 protein
  • Cspg2 protein
  • cspg2a protein
  • cspg2b protein
  • dcan protein
  • DPEAAE protein
  • ERVR protein
  • fb99b07 protein
  • GHAP protein
  • hdf protein
  • NG2 protein
  • PG-M protein
  • PG-M(V0) protein
  • PG-M(V1) protein
  • sb:cb63 protein
  • VCAN protein
  • versican protein
  • WGN protein
  • WGN1 protein
  • wu:fb99b07 protein
  • Xversican protein

Protein level used designations for Versican Proteins (Vcan)

chondroitin sulfate proteoglycan 2a , chondroitin sulfate proteoglycan 2b , dermacan , chondroitin sulfate proteoglycan 2 (versican) , chondroitin sulfate proteoglycan 2 , versican , versican core protein-like , chondroitin sulfate proteoglycan core protein 2 , glial hyaluronate-binding protein , large fibroblast proteoglycan , versican core protein , versican proteoglycan , PG-M core protein , Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) , heart defect , GHAP , PG-M , proteoglycan

GENE ID SPECIES
116993 Danio rerio
323465 Danio rerio
461766 Pan troglodytes
100101672 Xenopus (Silurana) tropicalis
445009 Canis lupus familiaris
100442387 Pongo abelii
100604867 Nomascus leucogenys
1462 Homo sapiens
13003 Mus musculus
114122 Rattus norvegicus
282662 Bos taurus
395565 Gallus gallus
488922 Canis lupus familiaris
397328 Sus scrofa
100727549 Cavia porcellus
100008666 Oryctolagus cuniculus
100294605 Ovis aries
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