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Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC) (By similarity). Additionally we are shipping Very Low Density Lipoprotein Kits (13) and Very Low Density Lipoprotein Antibodies (9) and many more products for this protein.
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Severe cobalamin depletion in the central nervous system (CNS) after birth in TCblR (show CD320 Proteins) knockouts indicates that TCblR (show CD320 Proteins) is the only receptor responsible for cobalamin uptake in the CNS
In vivo, endogenous PCSK9 (show PCSK9 Proteins) regulates VLDLR (show VLDLR Proteins) protein levels and triglyceride accumulation in adipose tissue.
Diabetic rats showed severe hyperlipidemia on d 21 and 28, with a dramatic decline in VLDL-R (show VLDLR Proteins) protein in skeletal muscle (>90%), heart (approximately 50%) and a loss of adipose tissues itself.
Reelin (show RELN Proteins) binds several receptors, including the VLDL receptor (show VLDLR Proteins) in cultured hippocampus neurons.
VLDL and LDL lowering by gene transfer of the VLDL receptor (show VLDLR Proteins) combined with a low-fat diet regimen induces regression and reduces macrophage content in advanced atherosclerotic lesions in LDL receptor (show LDLR Proteins)-deficient mice
These data demonstrate a cell-autonomous function of ApoER2 (show LRP8 Proteins), and most likely VLDLR (show VLDLR Proteins) and Dab1 (show DAB1 Proteins), in postnatal migration of neuroblasts in the forebrain, which is suggested to depend on ligands other than Reelin (show RELN Proteins).
The high affinity of apoE4 to the LDLR (show LDLR Proteins) enhances VLDL sequestration on the hepatocyte surface but delays their internalization.
Data show that thrombospondin-1 (THBS-1 (show THBS1 Proteins)) is a novel physiological ligand for ApoER2 (show LRP8 Proteins) and VLDLR (show VLDLR Proteins), and that lack of THBS-1 (show THBS1 Proteins) results in anatomical abnormalities of the RMS and leads to a reduction of postnatal neuronal precursors entering the OB.
Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC) (By similarity). CD320 augments the proliferation of PC precursors generated by IL-10 (By similarity). Receptor for the cellular uptake of transcobalamin bound cobalamin (By similarity).
, putative VLDL lipoprotein receptor
, transcobalamin receptor