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The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Additionally we are shipping VLDLR Antibodies (92) and VLDLR Kits (42) and many more products for this protein.
Showing 8 out of 8 products:
Human VLDLR Protein expressed in Human Cells - ABIN2003915
Trommsdorff, Gotthardt, Hiesberger, Shelton, Stockinger, Nimpf, Hammer, Richardson, Herz: Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2. in Cell 1999
Show all 5 references for ABIN2003915
These results for the first time demonstrated that SalA protected against IS/RP-induced endothelial barrier dysfunction through suppression of VLDL receptor expression
these results suggest that VLDLR functions in vivo as an HCV receptor independent of canonical CD81 (show CD81 Proteins)-mediated HCV entry.
the results obtained indicate that minimal fibrin-binding structures are located within the second and third CR domains of the VLDL receptor and the presence of the fourth CR domain is required for high-affinity binding
The results of this study demonstrated the presence of reelin (show RELN Proteins), its receptors VLDLR and ApoER2 (show LRP8 Proteins) as well as Dab1 (show DAB1 Proteins) in the ENS and might indicate a novel role of the reelin (show RELN Proteins) system in regulating neuronal plasticity and pre-synaptic functions in the ENS.
these results suggested that the miR (show MLXIP Proteins)-135a-VLDLR-p38 (show CRK Proteins) axis may contribute to gallbladder cancer cell proliferation
study identified a novel homozygous VLDLR c.2248C>T mutation (p.Q750X) and distinctive MRI (show C7ORF49 Proteins) findings in 2 siblings with ataxia (show USP14 Proteins); also marked vitamin E deficiency was detected in the proband
these results identify a novel role for the VLDLR as a negative regulator of DC-mediated adaptive immune responses in HDM (show HDAC3 Proteins)-induced allergic airway inflammation.
ectopic expression of HIC1 (show HIC1 Proteins) in U2OS and MDA-MB-231 cell lines decreases expression of the ApoER2 (show LRP8 Proteins) and VLDLR genes, encoding two canonical tyrosine kinase (show TXK Proteins) receptors for Reelin (show RELN Proteins).
an unusual constellation of VLDLR mutations in Cerebellar ataxia (show USP14 Proteins), mental retardation and dysequilibrium syndrome 1 is reported
Results show variation in VLDLR is implicated in disordered gambling
The absence of PCSK9 (show PCSK9 Proteins) results in a sex- and tissue-specific subcellular distribution of the LDLR (show LDLR Proteins) and VLDLR, which is determined by estradiol levels.
In the retinas of Vldlr(-/-) mice with low fatty acid uptake but high circulating lipid levels, we found that Ffar1 suppresses expression of the glucose transporter Glut1 (show SLC2A1 Proteins)
neuronal stress differentially regulates lipoprotein receptor expression in neurons, with VLDLR upregulation as a common element as a modulator of neuronal Wnt (show WNT2 Proteins) signaling
Subretinal vascularization (SRV) in the Vldlr-/- model is associated with mistargeted neurites and that SRV is preceded by altered retinal vascular development.
VLDLR requires RasGRF1 (show RASGRF1 Proteins)/CaMKII (show CAMK2G Proteins) to alter dendritic spine formation.
This study demonstrated that VLDLR is expressed in distinct spatiotemporal patterns in developing mouse cerebral cortex.
LRP5 (show LRP5 Proteins) signaling is a prerequisite for neovascularization in VLDLR knockout mice. LRP5 (show LRP5 Proteins) may be an effective target for inhibiting intraretinal neovascularization.
Nuclear factor (erythroid-derived 2)-like 2 (show NFE2L2 Proteins) activation-induced hepatic very-low-density lipoprotein receptor overexpression in response to oxidative stress contributes to alcoholic liver disease in mice.
Clusterin (show CLU Proteins) is a ligand for apolipoprotein E receptor 2 (ApoER2 (show LRP8 Proteins)) and very low density lipoprotein receptor (VLDLR) and signals via the Reelin (show RELN Proteins)-signaling pathway.
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene.
, very low-density lipoprotein receptor
, VTG receptor
, very low density lipoprotein (VLDL)/vitellogenin receptor
, vitellogenin receptor