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Vinculin (VCL) ELISA Kits

Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Additionally we are shipping Vinculin Antibodies (187) and Vinculin Proteins (13) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
VCL 7414 P18206
VCL 22330 Q64727
VCL 305679 P85972
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Top Vinculin ELISA Kits at antibodies-online.com

Showing 10 out of 42 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 31 pg/mL 78.13-5000 pg/mL 96 Tests Log in to see 9 to 11 Days
$700.00
Details
Mouse 0.105 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 9 to 11 Days
$720.00
Details
Pig 15.63 pg/ml 4000-62.5 pg/mL   96 Tests Log in to see 11 to 13 Days
$1,026.67
Details
Monkey
  96 Tests Log in to see 8 to 9 Days
$770.00
Details
Chicken
  96 Tests Log in to see 8 to 9 Days
$770.00
Details
Guinea Pig
  96 Tests Log in to see 8 to 9 Days
$770.00
Details
Rabbit
  96 Tests Log in to see 8 to 9 Days
$770.00
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Rat
  96 Tests Log in to see 11 to 13 Days
$785.71
Details
Dog
  96 Tests Log in to see 11 to 13 Days
$801.43
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Goat
  96 Tests Log in to see 11 to 13 Days
$801.43
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More ELISA Kits for Vinculin Interaction Partners

Human Vinculin (VCL) interaction partners

  1. The VCL-encoding protein was involved in cardiomyopathy that associated with hypertension, therefore our results suggest the rs4746172 of VCL may be a novel target for clinical interventions to reduce CVD risk by regulating blood pressure in male Chinese

  2. Three novel genes were identified as recurrently mutated; MYCN (show MYCN ELISA Kits), MYO5B and VCL, and mutations in these genes were exclusively found in malignant sympathetic paraganglioma tumors.

  3. roles and mechanisms of phospholipids in regulating the structure and function of vinculin and of its muscle-specific (show EIF3K ELISA Kits) metavinculin splice variant.

  4. Upon actin engagement, the N-terminal "strap" and helix 1 are displaced from the vinculin tail helical bundle to mediate actin bundling.

  5. This study defined a plastic relationship between vinculin-mediated tension and adhesion complex area that controls fundamental cell-matrix adhesion properties.

  6. Analysis showed that ITGB4 (show ITGB4 ELISA Kits) and VCL were upregulated in exosomes derived from taxane-resistant prostate cancer cells suggesting them as useful markers for progression of prostate cancer associated with taxane-resistance.

  7. vinculin, present in the joints of anti-citrullinated protein antibody (ACPA (show PRTN3 ELISA Kits))(+) rheumatoid arthritis patients, was identified as an autoantigen targeted by ACPA (show PRTN3 ELISA Kits) and CD4 (show CD4 ELISA Kits)(+) T cells.

  8. The activation of vinculin by stretched talin induces a positive feedback that reinforces the actin-talin-vinculin association.

  9. Data indicate that specific protein interactions are spatially segregated within focal adhesions (FAs (show FAS ELISA Kits)) at the nanoscale to regulate vinculin activation and function.

  10. Vinculin expression was found to be significantly downregulated.

Mouse (Murine) Vinculin (VCL) interaction partners

  1. Binding of vinculin to the R1-R3 region of the talin rod is important for focal adhesion stability.

  2. These data demonstrate that Src-mediated phosphorylation is necessary for vinculin activation, and that phosphorylation controls cytoskeletal mechanics by regulating force transmission between the actin cytoskeleton and focal adhesion proteins.

  3. results suggest that vinculin promotes directionally persistent cell migration and tension-dependent ECM (show MMRN1 ELISA Kits) remodeling in complex 3D environments by increasing cell-ECM (show MMRN1 ELISA Kits) adhesion and traction force generation.

  4. Force-dependent conformational switch of alpha-catenin (show CTNNA1 ELISA Kits) controls vinculin binding.

  5. Mutant vinculin expressing cells are altered in cell migration, which is accompanied by changes in cell adhesion.

  6. show that Src (show SRC ELISA Kits) phosphorylation of Y1065 within the C-terminal hairpin regulates Vt-mediated actin bundling and provide a detailed characterization of vinculin Y1065 mutations

  7. The E29R mutation might prime the vinculin head for F-actin binding, which results in higher cell stiffness, contractile force, and strengthening of focal adhesions.

  8. Vcl plays a crucial role in stabilizing gap junctions and myocyte integrity through direct interactions with ZO-1 (show TJP1 ELISA Kits) and stabilization of CX43 (show GJA1 ELISA Kits).

  9. serine phosphorylation is required for the activation of vinculin and force transmission in focal adhesions.

  10. VCL binding talin, but not Arp2 (show AICDA ELISA Kits)/3, is critical for osteoclast function, and its selective inhibition retards physiological bone loss.

Pig (Porcine) Vinculin (VCL) interaction partners

  1. Results suggest that myosin VI (show MYO6 ELISA Kits) and vinculin form a molecular apparatus that generates cohesive cell-cell contacts in cultured mammalian epithelia.

Vinculin (VCL) Antigen Profile

Antigen Summary

Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.

Gene names and symbols associated with Vinculin (VCL) ELISA Kits

  • vinculin (VCL) antibody
  • vinculin (vcl) antibody
  • vinculin A (vinA) antibody
  • Vinculin (Vinc) antibody
  • vinculin (CpipJ_CPIJ013873) antibody
  • vinculin (LOC100228062) antibody
  • vinculin (LOC100356093) antibody
  • vinculin (Vcl) antibody
  • vinculin (Bm1_37935) antibody
  • 9430097D22 antibody
  • AA571387 antibody
  • AI462105 antibody
  • AW545629 antibody
  • CG3299 antibody
  • CMD1W antibody
  • CMH15 antibody
  • CT11081 antibody
  • DDBDRAFT_0186762 antibody
  • DDBDRAFT_0232320 antibody
  • DDB_0186762 antibody
  • DDB_0232320 antibody
  • Dmel\\CG3299 antibody
  • Dmvincp antibody
  • EG:103B4.1 antibody
  • hm:zehn2160 antibody
  • im:6902790 antibody
  • LOC100228062 antibody
  • MV antibody
  • MVCL antibody
  • VCL antibody
  • vcl-A antibody
  • Vin antibody
  • Vin2EF antibody
  • vinc antibody

Protein level used designations for Vinculin (VCL) ELISA Kits

vinculin , CG3299-PA , Vinc-PA , vinculin at 2EF , vinculin-like , metavinculin , vinculin/metavinculin

GENE ID SPECIES
100064165 Equus caballus
450531 Pan troglodytes
552980 Danio rerio
8625369 Dictyostelium discoideum AX4
31201 Drosophila melanogaster
6047004 Culex quinquefasciatus
100036705 Xenopus (Silurana) tropicalis
100228062 Taeniopygia guttata
100410985 Callithrix jacchus
100476722 Ailuropoda melanoleuca
714312 Macaca mulatta
721921 Macaca mulatta
100075715 Ornithorhynchus anatinus
100583187 Nomascus leucogenys
7414 Homo sapiens
396422 Gallus gallus
100356093 Oryctolagus cuniculus
22330 Mus musculus
305679 Rattus norvegicus
783645 Bos taurus
373770 Xenopus laevis
100302597 Meleagris gallopavo
479252 Canis lupus familiaris
100357160 Oryctolagus cuniculus
396974 Sus scrofa
100722183 Cavia porcellus
101121312 Ovis aries
6102471 Brugia malayi
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