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anti-Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1) Antibodies

Vitamin K is essential for blood clotting but must be enzymatically activated. Additionally we are shipping VKORC1 Kits (7) and VKORC1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
VKORC1 79001 Q9BQB6
VKORC1 27973 Q9CRC0
VKORC1 309004 Q6TEK4
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Top anti-VKORC1 Antibodies at antibodies-online.com

Showing 10 out of 27 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Immunohistochemistry of VKORC1 in human lung tissue with VKORC1 antibody at 2.5 ug/mL. Western blot analysis of VKORC1 in A549 cell lysate with VKORC1 antibody at 1 ug/mL. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IHC (fro), WB   0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated IHC (p), WB VKORC1 Antibody (N-term) (ABIN652040) western blot analysis in NCI-H460 cell line lysates (35 µg/lane). This demonstrates the VKORC1 antibody detected the VKORC1 protein (arrow). VKORC1 Antibody (N-term) (ABIN652040) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-VKORC1 AntibodyTitration: 1.0 µg/mL  Positive Control: Fetal Brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of VKORC1 in A549 cell lysate with VKORC1 antibody at 1 µg/mL. 0.1 mg Log in to see 2 to 3 Days
$330.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details
Human Rabbit FITC IHC, ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details

VKORC1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,


, , , , ,
Mouse (Murine)



Rat (Rattus)



Top referenced anti-VKORC1 Antibodies

  1. Human Polyclonal VKORC1 Primary Antibody for EIA, IHC (fro) - ABIN493558 : Li, Chang, Jin, Lin, Khvorova, Stafford: Identification of the gene for vitamin K epoxide reductase. in Nature 2004 (PubMed)
    Show all 3 references for ABIN493558

  2. Human Polyclonal VKORC1 Primary Antibody for EIA, IF - ABIN1450145 : Oldenburg, Bevans, Müller, Watzka: Vitamin K epoxide reductase complex subunit 1 (VKORC1): the key protein of the vitamin K cycle. in Antioxidants & redox signaling 2006 (PubMed)

More Antibodies against VKORC1 Interaction Partners

Human Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1) interaction partners

  1. VKORC1S1639 GG and the wild type CYP2C9 (show CYP2C9 Antibodies)*1*1genotypes are associated with the high-dose requirement for warfarin therapy.

  2. A protein homology model of human VKORC1 was constructed to elucidate the binding modes of vitamin K 2,3-epoxide, R-warfarin, & S-warfarin in wild-type & mutant VKORC1 enzymes. Structural analysis of each model in conjunction with automated in-silico docking, provided a mechanism that explains warfarin resistance associated with the Val66Met & other VKORC1 polymorphisms.

  3. This study explored the correlations of VKORC1-1639 G/A, 1173 C/T and 497 T/G genetic polymorphisms with warfarin maintenance dose requirement in patients undergoing cardiac valve

  4. we identified differences in the frequency distribution in the Tibetan population located in the ALOX5 (show ALOX5 Antibodies) , VKORC1 and PTGS2 (show PTGS2 Antibodies) genes

  5. Our meta-analysis provides strong evidence that two SNPs in the VKORC1 gene, rs2359612 and rs9923231, contribute to the risk of cardiovascular and cerebrovascular diseases.

  6. ESR1 (show ESR1 Antibodies) and VKORC1 single nucleotide polymorphisms were used to determine the vitamin K dosage in patients with ulcer-related hemorrhage.

  7. In this study, we investigated two VKORC1 gene polymorphisms, -1639G/A and 1173C/T, for effects on warfarin maintenance dosage in valvular heart disease (VHD) patients

  8. Patients with VKORC1-1639A allele were more likely to require lower doses of both drugs than patients with the G allele (Odds ratio [OR] for acenocoumarol 9.06, and OR for warfarin = 18.7).

  9. presence of CYP2C9 (show CYP2C9 Antibodies)*3 or VKORC1*2 gene polymorphism were associated with decrease in acenocoumarol dose requirements

  10. performed tests of association between five common VKORC1 SNPs and two different measurements of vitamin K levels, dietary (n=5,725) and serum (n=348), in the Third National Health and Nutrition Examination Studies (NHANES III)

Mouse (Murine) Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1) interaction partners

  1. quantified mRNA levels for VKORC1, VKORC1L1, GGCX (show GGCX Antibodies), and NQO1 (show NQO1 Antibodies) and measured VKOR enzymatic activities in 29 different tissues

  2. OCN is gamma-carboxylated by the gamma-carboxylase (GGCX (show GGCX Antibodies)) on three glutamic acid residues, a cellular process requiring reduction of vitamin K by a second enzyme, VKORC1.

  3. The involvement of VKORC1L1 in VKOR activity partly explains the low susceptibility of some extrahepatic tissues to vitamin K antagonists.

  4. molecular cloning [VKORC1]

  5. The genetic basis for resistance to anticoagulants lies in mutations in Vkorc1.

  6. An analysis of novel mutations show that the VKORC1 gene is the main target for spontaneous mutations conferring warfarin resistance.

  7. Each VKORC1 T-allele present in patients from the Rotterdam anticoagulation therapy study is shown to decrease the required acenocoumarol dosage by 5.1 mg/week.

VKORC1 Antigen Profile

Protein Summary

Vitamin K is essential for blood clotting but must be enzymatically activated. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. The product of this gene encodes the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is the product of this gene that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance. Two pseudogenes have been identified on chromosome 1 and the X chromosome. Two alternatively spliced transcripts encoding different isoforms have been described.

Gene names and symbols associated with VKORC1

  • vitamin K epoxide reductase complex, subunit 1 (VKORC1) antibody
  • vitamin K epoxide reductase complex subunit 1 (vkorc1) antibody
  • vitamin K epoxide reductase complex, subunit 1 (vkorc1) antibody
  • Vitamin-K epoxide reductase (Vkor) antibody
  • vitamin K epoxide reductase complex, subunit 1 (Vkorc1) antibody
  • BP1071 antibody
  • CG33544 antibody
  • D7Wsu86e antibody
  • Dmel\\CG33544 antibody
  • EDTP308 antibody
  • HDC06808 antibody
  • IMAGE3455200 antibody
  • MGC89620 antibody
  • MST134 antibody
  • MST576 antibody
  • VKCFD2 antibody
  • VKOR antibody
  • VKORC1 antibody

Protein level used designations for VKORC1

phylloquinone epoxide reductase , vitamin K1 epoxide reductase (warfarin-sensitive) , vitamin K epoxide reductase complex, subunit 1 , CG33544-PA , Vkor-PA , vitamin K dependent clotting factors deficiency 2 , vitamin K epoxide reductase complex subunit 1 , vitamin K1 2,3-epoxide reductase subunit 1 , Warfarin resistance

GENE ID SPECIES
404205 Gallus gallus
446034 Takifugu rubripes
448775 Xenopus (Silurana) tropicalis
479775 Canis lupus familiaris
3346188 Drosophila melanogaster
79001 Homo sapiens
27973 Mus musculus
309004 Rattus norvegicus
445422 Bos taurus
Selected quality suppliers for anti-VKORC1 (VKORC1) Antibodies
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