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anti-Voltage-Dependent Anion Channel 2 (VDAC2) Antibodies

VDAC2 encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. Additionally we are shipping VDAC2 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
VDAC2 7417 P45880
VDAC2 22334 Q60930
VDAC2 83531 P81155
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Top anti-VDAC2 Antibodies at antibodies-online.com

Showing 10 out of 63 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-VDAC2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: 293T cell lysate Host: Rabbit  Target Name: VDAC2  Sample Tissue: Human Fetal Brain  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-VDAC2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Transfected 293T Rabbit Anti-VDAC2 Antibody ,Paraffin Embedded Tissue: Human Bronchial Epithelial Tissue 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Goat Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Dog Goat Un-conjugated WB 20 μg Log in to see 6 to 8 Days
$203.50
Details
Human Goat Un-conjugated ELISA, WB ABIN185705 (0.3 ug/ml) staining of Human Heart lysate (35 ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Goat Un-conjugated ELISA, WB ABIN185206 (0.3 ug/ml) staining of Human Testis lysate (35 ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. ABIN185206 (1 µg/mL) staining of Human Brain (Cerebellum) lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Mouse Un-conjugated WB Western Blot analysis of VDAC2 expression in transfected 293T cell line by VDAC2 monoclonal antibody (M01), clone 3D2. Lane 1: VDAC2 transfected lysate(31.6 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated ICC, IF, IP, IHC (p), ELISA, WB IHC-P Image VDAC2 antibody [C2C3], C-term detects VDAC2 protein at mitochondria on human normal liver by immunohistochemical analysis. Sample: Paraffin-embedded normal liver. VDAC2 antibody [C2C3], C-term , dilution: 1:250. IP Image VDAC2 antibody [C2C3], C-term immunoprecipitates VDAC2 protein in IP experiments. IP samples: HepG2 whole cell extract A. Control with 4 μg of preimmune Rabbit IgG B. Immunoprecipitation of VDAC2 protein by 4 μg VDAC2 antibody [C2C3], C-term , 10 % SDS-PAGE The immunoprecipitated VDAC2 protein was detected by VDAC2 antibody [C2C3], C-term , diluted at 1:1000. [EasyBlot anti-rabbit IgG  was used as a secondary reagent] 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IHC (p), WB Human Skeletal Muscle (formalin-fixed, paraffin-embedded) stained with VDAC2 antibody ABIN213732 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with VDAC2 antibody ABIN213732 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details

VDAC2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus) ,
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Top referenced anti-VDAC2 Antibodies

  1. Human Monoclonal VDAC2 Primary Antibody for WB - ABIN395945 : De Pinto, Guarino, Guarnera, Messina, Reina, Tomasello, Palermo, Mazzoni: Characterization of human VDAC isoforms: a peculiar function for VDAC3? in Biochimica et biophysica acta 2010 (PubMed)
    Show all 5 references for ABIN395945

  2. Cow (Bovine) Polyclonal VDAC2 Primary Antibody for EIA, IHC (p) - ABIN374420 : Blachly-Dyson, Zambronicz, Yu, Adams, McCabe, Adelman, Colombini, Forte: Cloning and functional expression in yeast of two human isoforms of the outer mitochondrial membrane channel, the voltage-dependent anion channel. in The Journal of biological chemistry 1993 (PubMed)
    Show all 2 references for ABIN374420

  3. Chicken Polyclonal VDAC2 Primary Antibody for WB - ABIN2776154 : Chandra, Choy, Daniel, Tang: Bax-dependent regulation of Bak by voltage-dependent anion channel 2. in The Journal of biological chemistry 2005 (PubMed)
    Show all 2 references for ABIN2776154

  4. Chicken Polyclonal VDAC2 Primary Antibody for WB - ABIN2776155 : Valis, Neubauerova, Man, Pompach, Vohradsky, Kovar: VDAC2 and aldolase A identified as membrane proteins of K562 cells with increased expression under iron deprivation. in Molecular and cellular biochemistry 2008 (PubMed)

More Antibodies against VDAC2 Interaction Partners

Arabidopsis thaliana Voltage-Dependent Anion Channel 2 (VDAC2) interaction partners

  1. AtVDAC2 has a main function in mitochondria

  2. VDAC2 and VDAC4 are important for leaf development, the mitochondrial membrane potential, and pollen development.

Human Voltage-Dependent Anion Channel 2 (VDAC2) interaction partners

  1. The works available on VDAC cysteines support the notion that VDAC1 (show VDAC1 Antibodies), VDAC2, and VDAC3 (show VDAC3 Antibodies) proteins are paralogs with a similar pore-function and slightly different, but important, ancillary biological functions. (Review)

  2. The evolutionary demand for the NTE (show PNPLA6 Antibodies) in the presence of cysteines clearly emerges from our biochemical and functional studies, providing insight into factors that functionally demarcate hVDAC-2 from the other VDACs.

  3. Motifs of VDAC2 required for mitochondrial Bak (show BAK1 Antibodies) import and tBid-induced apoptosis.

  4. Results show that in thyroid tumours and cell lines, VDAC2 is upregulated and BAK1 (show BAK1 Antibodies) downregulated. Also, transient knockdown of VDAC2 promoted upregulation of the BAK1 (show BAK1 Antibodies) expression, and increased susceptibility to sorafenib treatment.

  5. These data suggest that an interaction between Mcl-1 (show MCL1 Antibodies) and VDAC promotes lung cancer cell migration by a mechanism that involves Ca(2 (show CA2 Antibodies)+)-dependent reactive oxygen species production.

  6. RACK1 (show GNB2L1 Antibodies) plays an antiapoptotic role during IBDV infection via interaction with VDAC2 and VP5.

  7. GSK-3beta (show GSK3b Antibodies) translocates from the cytosol to mitochondria in a kinase activity- and VDAC2-dependent manner in which an N-terminal domain of GSK-3beta (show GSK3b Antibodies) may function as a mitochondrial targeting sequence

  8. Cysteine residues impact the stability and micelle interaction dynamics of the human mitochondrial beta-barrel anion channel VDAC-2.

  9. minor conformational variations in local residues are sufficient to define the membrane protein dynamics in hVDAC-2.

  10. The reconstitution of functional VDAC-2 in lauryldimethylamine-oxide (LDAO) detergent micelles and 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) lipid bilayer nanodiscs, is reported.

Cow (Bovine) Voltage-Dependent Anion Channel 2 (VDAC2) interaction partners

  1. ENO1 (show ENO1 Antibodies), VDAC2, and UQCRC2 (show UQCRC2 Antibodies) were significantly correlated with individual fertility in bulls.

  2. Results describe the expression of voltage-dependent anion channel isoforms in rat, bovine, and chicken brain mitochondria, and suggest that the nature of hexokinase binding site is not determined by the expression of a single VDAC isoform.

  3. VDAC2 and VDAC3 (show VDAC3 Antibodies) might have an alternative structural organization and different functions in outer dense fibers (show ODF1 Antibodies) than in mitochondria

  4. Confirm the localisation of VDAC2 in the acrosomal region of bovine spermatozoa using immunoelectron microscopy.

  5. The present study is the first work to report the purification and characterization of VDAC2 from a mammalian tissue.

Mouse (Murine) Voltage-Dependent Anion Channel 2 (VDAC2) interaction partners

  1. an important MYBL2 (show MYBL2 Antibodies)-VDAC2-BECN1 (show BECN1 Antibodies)-BCL2L1 (show BCL2L1 Antibodies) pathway linking autophagy suppression in the developing ovary, is reported.

  2. Motifs of VDAC2 required for mitochondrial Bak (show BAK1 Antibodies) import and tBid-induced apoptosis.

  3. Bax (show BAX Antibodies) localizes to the mitochondrial outer membrane via alternate mechanisms, either constitutively via an interaction with VDAC2 or after activation via interaction with Bcl-2 (show BCL2 Antibodies) family proteins.

  4. Bcl-xL (show BCL2L1 Antibodies) interacts functionally with VDAC1 (show VDAC1 Antibodies) and -3 but not VDAC2.

  5. VDAC2 acts as a crucial component in mitochondrial apoptosis by allowing the mitochondrial recruitment of BAK (show BAK1 Antibodies), thereby controlling tBID-induced OMM permeabilization and cell death.

  6. VDAC2 regulates the activity of BAK (show BAK1 Antibodies) and provides a connection between mitochondrial physiology and the core apoptotic pathway

  7. Vdacs are dispensable for both MPT and Bcl-2 (show BCL2 Antibodies) family member-driven cell death.

  8. Genetic depletion of Vdac2 in the thymus resulted in excessive cell death & hypersensitivity to diverse death stimuli including engagement of the T cell receptor. The VDAC2-BAK (show BAK1 Antibodies) axis governs the homeostasis of thymocytes.

Zebrafish Voltage-Dependent Anion Channel 2 (VDAC2) interaction partners

  1. These findings demonstrate a critical modulatory role for VDAC2-dependent mitochondrial Ca(2 (show CA2 Antibodies)+) uptake in the regulation of cardiac rhythmicity.

  2. Data indicate the structure of voltage-dependent anion channel 2 zfVDAC2 at 2.8 A resolution, revealing a crystallographic dimer.

Pig (Porcine) Voltage-Dependent Anion Channel 2 (VDAC2) interaction partners

  1. an important MYBL2 (show MYBL2 Antibodies)-VDAC2-BECN1 (show BECN1 Antibodies)-BCL2L1 (show BCL2L1 Antibodies) pathway linking autophagy suppression in the developing ovary, is reported.

  2. Data confirm the synthesis of VDAC1 (show VDAC1 Antibodies) and 2 subtypes in GV (germinal vesicle) and MII (meiosis II) stage porcine oocytes as well as their protein expression.

VDAC2 Antigen Profile

Protein Summary

This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in the mitochondrial apoptotic pathway via regulation of BCL2-antagonist/killer 1 protein activity. Pseudogenes have been identified on chromosomes 1, 2, 12 and 21, and alternative splicing results in multiple transcript variants.

Gene names and symbols associated with VDAC2

  • voltage-dependent anion-selective channel protein 2-like (LOC100540440) antibody
  • voltage-dependent anion channel 2 (vdac2) antibody
  • voltage-dependent anion channel 2 (VDAC2) antibody
  • voltage dependent anion channel 2 (VDAC2) antibody
  • voltage-dependent anion channel 2 (Vdac2) antibody
  • ARABIDOPSIS THALIANA VOLTAGE DEPENDENT ANION CHANNEL 2 antibody
  • ATVDAC2 antibody
  • K9I9.6 antibody
  • K9I9_6 antibody
  • mVDAC2 antibody
  • mVDAC6 antibody
  • POR antibody
  • VDAC2 antibody
  • Vdac6 antibody
  • voltage dependent anion channel 2 antibody
  • wu:fa01a08 antibody
  • wu:fa98a10 antibody
  • wu:fb50g11 antibody
  • zgc:55795 antibody
  • zgc:77621 antibody

Protein level used designations for VDAC2

voltage-dependent anion channel 2 , voltage-dependent anion-selective channel protein 2 , outer mitochondrial membrane protein porin 2 , VDAC-2 , VDAC-6 , voltage-dependent anion-selective channel protein 6 , B36-VDAC , outer mitochondrial membrane protein porin

GENE ID SPECIES
100540440 Meleagris gallopavo
548947 Xenopus (Silurana) tropicalis
738876 Pan troglodytes
100528960 Ictalurus punctatus
836886 Arabidopsis thaliana
7417 Homo sapiens
282120 Bos taurus
100009473 Oryctolagus cuniculus
22334 Mus musculus
83531 Rattus norvegicus
322126 Danio rerio
734449 Xenopus laevis
395498 Gallus gallus
479255 Canis lupus familiaris
397659 Sus scrofa
101092793 Felis catus
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