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Von Hippel-Lindau Tumor Suppressor (VHL) ELISA Kits

may act as a tumor suppressor [RGD, Feb 2006].. Additionally we are shipping VHL Antibodies (14) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
VHL 24874 Q64259
Anti-Mouse VHL VHL 22346 P40338
VHL    
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Top VHL ELISA Kits at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 5.86 pg/ml 23.44-1500 pg/mL 96 Tests Log in to see 11 to 13 Days
$910.56
Details
Rat 0.113 ng/mL 0.313-20 ng/mL 96 Tests Log in to see 5 to 9 Days
$1,093.63
Details

More ELISA Kits for VHL Interaction Partners

Fruit Fly (Drosophila melanogaster) Von Hippel-Lindau Tumor Suppressor (VHL) interaction partners

  1. Interaction between Nm23 (show NME1 ELISA Kits) and the tumor suppressor VHL

  2. Transgenic pVHL can fully maintain normal dVHL-HIF1-alpha (show HIF1A ELISA Kits) downstream pathways in flies.

  3. Codepletion of Vhl with Mgr (show GRHL1 ELISA Kits) gives partial rescue of tubulin (show TUBB ELISA Kits) instability, monopolar spindle formation, and loss of centrosomes.

  4. The results establish a developmental function of the VHL gene that is relevant to its tumor-suppressor activity.

  5. findings reveal a second type of tracheal hypoxic response in which Sima activation conflicts with developmental tracheogenesis, and identify the dVHL and ago ubiquitin ligases as key determinants of hypoxia sensitivity in tracheal cells

Zebrafish Von Hippel-Lindau Tumor Suppressor (VHL) interaction partners

  1. Zebrafish embryos lacking endogenous vhl lead to defective phenotypes in the renal system that were characterized by the curved and cystic pronephric tubule or/and a cystic and malformed glomerulus.

  2. Inhibiting PHD (show PDC ELISA Kits) or knocking down VHL rescues Methyl tert (show TERT ELISA Kits)-butyl ether induced vascular lesions.

  3. Zebrafish vhl mutants display a marked increase in blood vessel formation throughout the embryo, and the most severe neovascularization is observed in distinct areas that overlap with high vegfa (show VEGFA ELISA Kits) mRNA expression, including the vhl mutant brain and eye.

  4. Vhl mutants develop polycythemia with increased epo (show EPO ELISA Kits)/epor (show EPOR ELISA Kits) mRNA & erythropoietin (show EPO ELISA Kits) signaling. VHL regulates hematopoiesis & erythroid differentiation. Zebrafish vhl mutants are the 1st congenital embryonic viable systemic vertebrate animal model for VHL.

Mouse (Murine) Von Hippel-Lindau Tumor Suppressor (VHL) interaction partners

  1. Loss of Vhl in mesenchymal progenitors of the limb bud caused severe fibrosis of the synovial joints and formation of aggressive masses with histologic features of mesenchymal tumors.

  2. These data suggested that intestinal epithelial cells were injured after IM treatment through the pVHL overexpression-induced degradation of collagen I or HIF-1alpha (show HIF1A ELISA Kits).

  3. Vhl and Kif3a (show KIF3A ELISA Kits) deletion accelerates renal cyst formation

  4. maintains the stability and suppressive function of Foxp3 (show FOXP3 ELISA Kits)+ T cells via regulation of HIF-1a (show HIF1A ELISA Kits) pathway

  5. Deletion of the Vhl gene causes sympathoadrenal cell death and impairs chemoreceptor-mediated adaptation to hypoxia.

  6. Molecular dynamics of hif-1alpha (show HIF1A ELISA Kits) and VHL may determine the success of antineoplastic strategies in hypoxia-reoxygenation as predicted by computational modeling.

  7. Loss of Vhl in adult joint cartilage is associated with earlier dysregulation of cartilage homeostasis, characterized by increased chondrocyte apoptosis, compromised chondrocyte autophagy and accelerated age-related and surgery-induced OA development.

  8. Both Vhl and Bap1 (show BAP1 ELISA Kits) are required for kidney function. Even when Vhl is inactivated in multipotent nephron progenitor cells, Vhl loss is insufficient for renal tumorigenesis.

  9. VHL deficiency perturbs pancreas endocrine homeostasis in mice.

  10. data suggest that the VHL-mediated signaling in osteochondral progenitor cells plays a critical role in bone remodeling at postnatal/adult stages through coupling osteogenesis and angiogenesis

VHL Antigen Profile

Antigen Summary

may act as a tumor suppressor

Gene names and symbols associated with VHL

  • von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase (Vhl) antibody
  • von Hippel-Lindau (Vhl) antibody
  • von Hippel-Lindau tumor suppressor (VHL) antibody
  • von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase (vhl) antibody
  • von Hippel-Lindau tumor suppressor (vhl) antibody
  • von Hippel-Lindau disease tumor suppressor (CpipJ_CPIJ009992) antibody
  • von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase (VHL) antibody
  • von Hippel-Lindau tumor suppressor (Vhl) antibody
  • BcDNA:RH61560 antibody
  • CG13221 antibody
  • d-vhl antibody
  • Dmel\\CG13221 antibody
  • dmVHL antibody
  • dVHL antibody
  • hrca1 antibody
  • rca1 antibody
  • vhl antibody
  • vhl1 antibody
  • Vhlh antibody
  • zgc:158722 antibody

Protein level used designations for VHL

pVHL , von Hippel-Lindau disease tumor suppressor , von Hippel-Lindau syndrome homolog , CG13221-PA , CG13221-PB , Vhl-PA , Vhl-PB , von hippel lindau , von hippel lindau protein , von Hippel-Lindau tumor suppressor , Von Hippel-Lindau disease tumor suppressor , von Hippel-Lindau syndrome protein homolog

GENE ID SPECIES
24874 Rattus norvegicus
53433 Drosophila melanogaster
416117 Gallus gallus
540957 Bos taurus
549121 Xenopus (Silurana) tropicalis
791202 Danio rerio
6042662 Culex quinquefasciatus
100173372 Pongo abelii
100380306 Salmo salar
22346 Mus musculus
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