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anti-Von Hippel-Lindau Tumor Suppressor-Like (VHLL) Antibodies

Von Hippel-Lindau (VHL) tumor suppressor protein is a component of an E3 ubiquitin ligase complex that selectively ubiquitinates the alpha subunit of the hypoxia-inducible factor (HIF) transcription factor for proteasome-mediated degradation. Additionally we are shipping Von Hippel-Lindau Tumor Suppressor-Like Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
VHLL 391104 Q6RSH7
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Top anti-Von Hippel-Lindau Tumor Suppressor-Like Antibodies at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated WB Immunohistochemical staining using von Hippel-Lindau antibody on formalin fixed, paraffin embedded human kidney tissue. 100 μg Log in to see 4 to 6 Days
$462.00
Details
Human Mouse Un-conjugated ELISA   500 μL Log in to see 11 to 16 Days
$515.43
Details
Human Mouse Un-conjugated WB Western Blot analysis of VHLL expression in transfected 293T cell line by VHLL MaxPab polyclonal antibody.Lane 1: VHLL transfected lysate(15.3 KDa).Lane 2: Non-transfected lysate. 50 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB   100 μL Log in to see 11 to 16 Days
$447.86
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL Log in to see 3 to 4 Days
$157.06
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 11 to 16 Days
$529.57
Details
Human Mouse Un-conjugated ELISA, WB   100 μg Log in to see 6 to 8 Days
$652.30
Details
Human Mouse Un-conjugated   5 μg Log in to see 6 Days
$168.54
Details

VHLL Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human ,
,
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Top referenced anti-Von Hippel-Lindau Tumor Suppressor-Like Antibodies

  1. Human Monoclonal VHLL Primary Antibody for WB - ABIN306858 : Kibel, Iliopoulos, DeCaprio, Kaelin: Binding of the von Hippel-Lindau tumor suppressor protein to Elongin B and C. in Science (New York, N.Y.) 1995 (PubMed)
    Show all 2 references for ABIN306858

Von Hippel-Lindau Tumor Suppressor-Like (VHLL) Antigen Profile

Protein Summary

Von Hippel-Lindau (VHL) tumor suppressor protein is a component of an E3 ubiquitin ligase complex that selectively ubiquitinates the alpha subunit of the hypoxia-inducible factor (HIF) transcription factor for proteasome-mediated degradation. Inactivation of VHL causes VHL disease and sporadic kidney cancer. This gene encodes a VHL homolog that lacks one of two key domains necessary for VHL function. This gene may contribute to the regulation of oxygen homeostasis and neovascularization during placenta development. This gene is intronless, and can also be interpreted as a retrotransposed pseudogene of the VHL locus located on chromosome 3. However, the protein is represented in this RefSeq due to evidence in PMID:14757845 that strongly suggests it is translated. The same publication also indicates that this protein binds HIF alpha but fails to recruit the E3 ubiquitin ligase complex, and it therefore functions as a dominant-negative VHL protein and a protector of HIF alpha.

Gene names and symbols associated with VHLL

  • von Hippel-Lindau tumor suppressor-like (VHLL) antibody
  • VHLP antibody
  • VLP antibody

Protein level used designations for VHLL

VHL pseudogene , VHL-like protein , von Hippel-Lindau-like protein

GENE ID SPECIES
391104 Homo sapiens
Selected quality suppliers for anti-Von Hippel-Lindau Tumor Suppressor-Like (VHLL) Antibodies
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