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The glycoprotein encoded by VWF functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. Additionally we are shipping VWF Kits (96) and VWF Proteins (23) and many more products for this protein.
Showing 10 out of 510 products:
Human Monoclonal VWF Primary Antibody for EIA, IHC (fro) - ABIN119340
am Orde, Glaesener, Exner, Gerner: [Results of extensive cervical laminectomy] in Zeitschrift für Orthopädie und ihre Grenzgebiete 1993
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Human Polyclonal VWF Primary Antibody for IHC (p), WB - ABIN3042328
Yang, Qin, Wang, Chen, Yuan, Fang, Yao, Jiao, Yu, Zhang, Wang: Pinocembrin, a major flavonoid in propolis, improves the biological functions of EPCs derived from rat bone marrow through the PI3K-eNOS-NO signaling pathway. in Cytotechnology 2013
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Mouse (Murine) Polyclonal VWF Primary Antibody for IHC (p), WB - ABIN3042349
Jiang, Xu, Zhu, Chen, Qian, Qiao, Yang, Wang, Chen: Histological type of oncogenity and expression of cell cycle genes in tumor cells from human mesenchymal stem cells. in Oncology reports 2006
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Human Monoclonal VWF Primary Antibody for IHC (p), Purif - ABIN2477114
Chand, McCraw, Hutton, Tuddenham, Goodall: A two-site, monoclonal antibody-based immunoassay for von Willebrand factor--demonstration that vWF function resides in a conformational epitope. in Thrombosis and haemostasis 1986
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Human Polyclonal VWF Primary Antibody for IHC (p) - ABIN115301
Bukh, Ingerslev, Stenbjerg, Muoller: The multimeric structure of plasma F VIII:RAg studied by electroelution and immunoperoxidase detection. in Thrombosis research 1986
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Human Monoclonal VWF Primary Antibody for IHC (fro), IHC (p) - ABIN114682
Naiem, Gerdes, Abdulaziz, Sunderland, Allington, Stein, Mason: The value of immunohistological screening in the production of monoclonal antibodies. in Journal of immunological methods 1982
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Human Polyclonal VWF Primary Antibody for IHC, ELISA - ABIN1585505
Wang, Fan, Yu, Liao, Zhao, Mandeville, Guo, Lo, Wang: Effects of tissue plasminogen activator and annexin A2 combination therapy on long-term neurological outcomes of rat focal embolic stroke. in Stroke; a journal of cerebral circulation 2014
Human Polyclonal VWF Primary Antibody for IF (cc), IF (p) - ABIN670506
Du, Wang, Zhao, Li, Kong, Yang, Zhang: Gradient nanofibrous chitosan/poly ?-caprolactone scaffolds as extracellular microenvironments for vascular tissue engineering. in Biomaterials 2011
level of vWF-ag in the chronic phase correlated with the amounts of VAT and PAT, but not with subcutaneous adipose tissue
both in acute and chronic cerebrovascular disease patients, ADAMTS13 (show ADAMTS13 Antibodies) levels were significantly decreased, with the lowest ADAMTS13 (show ADAMTS13 Antibodies) levels found in acute stroke patients. This difference was even more distinct when the ratio of VWF:ADAMTS13 was considered. These results demonstrate the potentially important involvement of the VWF/ADAMTS13 (show ADAMTS13 Antibodies) axis in ischemic stroke.
Erythrocyte retention in venous thrombi is mediated by erythrocyte-VWF or erythrocyte-VWF-fibrin interactions.
A novel single-domain antibody against von Willebrand factor A1 domain that interferes with VWF-platelet interactions in vivo. By using this sdAb, show that the A1 domain is pertinent to the participation of VWF in the inflammatory response.
Of special importance is the sequential formation of disulfide bonds with different functions in structural support of VWF multimers, which are packaged, stored and further processed after secretion. Here, all these processes are being reviewed in detail including background information on the occurring biochemical reactions. [review]
A subgroup of patients with end-stage heart failure already suffers AvWS preoperatively. In both CF-LVAD groups, AvWS begins immediately after surgery. Intraoperative vWF:ratios <0.7 correlate with higher incidences of pericardial tamponade and re-operation. The presumably dilutive effect of the heart lung machine on vWF vanishes immediately at the end of surgery, possibly as part of an acute-phase response
this studies show binding of VWF to C1q and thus a direct interaction between starter molecules of hemostasis and the classical pathway of complement
Elevated endothelium-related mediators (vWF, E-selectin (show SELE Antibodies) and EPCR (show PROCR Antibodies)) appear to participate in the development of pancreatic necrosis and may be a potential indicator of overall prognosis.
Plasma vWF levels are associated with tissue fibrosis in patients undergoing cardiac surgery and with post-surgical atrial fibrillation development in ischaemic patients.
a new role for AP-1 (show FOSB Antibodies) in the basolateral constitutive secretion of VWF.
alterations in glycosylation of vWF and other adhesion proteins associated with the targeting of the alpha1,3-Gal (show GAL Antibodies)-epitope in mutant swine may have salutatory effects on the primate platelet activation observed in these xenografts.
Hemodynamic activation of vWF and increased plasma ADAMTS-13 (show ADAMTS13 Antibodies) may have contributed to reduced high-molecular-weight vWF multimers and impairment of the vWF-platelet aggregation pathway during mechanical circulatory support.
both the gpIb-VWF interaction and the integrin alpha(2 (show ITGA2 Antibodies))beta(1)-collagen interaction contribute to platelet adhesion under high shear stress; integrin alpha(II (show GSTA3 Antibodies))beta(1) makes a greater contribution to adhesion to type I collagen because less VWF is bound
These experiments delineate an unexpected pathway in which microbiota-triggered TLR2 (show TLR2 Antibodies) signaling alters the synthesis of proadhesive VWF by the liver endothelium and favors platelet integrin-dependent thrombus growth.
ADAMTS13 (show ADAMTS13 Antibodies) controls vascular remodeling by modifying VWF reactivity during stroke recovery.
these novel findings support the hypothesis that conformation of the VWF A domains plays a critical role in modulating macrophage-mediated clearance of VWF in vivo.
results revealed localized vascular expression of FVIII (show F8 Antibodies) and von Willebrand factor and identified lymphatic endothelial cell as a major cellular source of FVIII (show F8 Antibodies) in extrahepatic tissues.
Endothelial cell derivedVWF is the major determinant that mediates VWF-dependent ischemic stroke by promoting postischemic thrombo-inflammation.
VWF deficiency reduces the progression of liver fibrosis, suggesting a mechanistic role of elevated plasma VWF levels in cirrhosis
von Willebrand factor exerts beneficial effects in a mouse sepsis model via recruitment of neutrophils to inflammatory sites.
Staphylococcus lugdunensis binds directly to von Willebrand factor, which proved to be vital for withstanding shear forces and for its adhesion to the vessel wall and cardiac valves.
Clinical experimental cerebral malaria progression was delayed, and overall survival was significantly prolonged in VWF(-/-) mice compared with WT controls.
The glycoprotein encoded by this gene functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. It is crucial to the hemostasis process. Mutations in this gene or deficiencies in this protein result in von Willebrand's disease. An unprocessed pseudogene has been found on chromosome 22.
von Willebrand factor
, coagulation factor VIII VWF