anti-Von Willebrand Factor (VWF) Antibodies

The glycoprotein encoded by VWF functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. Additionally we are shipping VWF Kits (104) and VWF Proteins (21) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
VWF 7450 P04275
VWF 116669  
VWF 22371 Q8CIZ8
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Top anti-VWF Antibodies at antibodies-online.com

Showing 10 out of 519 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IHC (fro), IHC (p) Formalin fixed paraffin embedded human tonsil stained with Factor VIII antibody ABIN114681 0.5 mL Log in to see 6 to 8 Days
$308.00
Details
Human Rabbit Un-conjugated IHC (p) Formalin fixed paraffin embedded human tonsil stained with Factor VIII R antigen polyclonal  rabbit antibody 0.5 mL Log in to see 6 to 8 Days
$253.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-VWF Picoband antibody,  All lanes: Anti-VWF at 0.5ug/ml WB:  Whole Cell Lysate at 40ug Predicted bind size: 309KD Observed bind size: 309KD Anti-VWF Picoband antibody,  IHC(P): Human Lung Cancer Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IF (cc), IF (p), IHC (p) Formalin-fixed and paraffin embedded rat brain tissue (ABIN670506) at 1:300 followed by conjugation to the secondary antibody and DAB staining. Formalin-fixed and paraffin embedded rat brain tissue  at 1:300 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
$318.45
Details
Human Rabbit Un-conjugated IHC, ELISA, WB VWF staining in rat brain. Formalin-fixed paraffin-embedded rat brain is stained with von Willebrand Factor Antibody used at 1:200 dilution. 0.1 mg Log in to see 2 to 6 Days
$327.00
Details
Mouse Rabbit Un-conjugated IHC (p), WB Anti- VWF Picoband antibody, IHC(P) IHC(P): Mouse Liver Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin-embedded human colon carcinoma labeled with Rabbit Anti-Von Willebrand Factor Polyclonal Antibody, Unconjugated(ABIN1714578) 1:200, overnight at 4 °C, The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37 °C. 100 μL Log in to see 14 to 21 Days
$306.90
Details
Human Sheep FITC IHC (fro), IF, IHC (p) Human Spleen, Endothelium: Formalin-Fixed, Paraffin-Embedded (FFPE). 50 μL Log in to see 6 to 8 Days
$368.50
Details
Human Mouse Un-conjugated IHC (p), Purif, RIA, ELISA 0.5 mg Log in to see 3 to 4 Days
$520.24
Details
All Species Mouse Un-conjugated ELISA, WB   0.25 mg Log in to see 7 to 9 Days
$866.81
Details

VWF Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-VWF Antibodies

  1. Human Polyclonal VWF Primary Antibody for IHC (p), WB - ABIN3042328 : Yang, Qin, Wang, Chen, Yuan, Fang, Yao, Jiao, Yu, Zhang, Wang: Pinocembrin, a major flavonoid in propolis, improves the biological functions of EPCs derived from rat bone marrow through the PI3K-eNOS-NO signaling pathway. in Cytotechnology 2013 (PubMed)
    Show all 5 Pubmed References

  2. Mouse (Murine) Polyclonal VWF Primary Antibody for IHC (p), WB - ABIN3042349 : Jiang, Xu, Zhu, Chen, Qian, Qiao, Yang, Wang, Chen: Histological type of oncogenity and expression of cell cycle genes in tumor cells from human mesenchymal stem cells. in Oncology reports 2006 (PubMed)
    Show all 5 Pubmed References

  3. Human Polyclonal VWF Primary Antibody for IHC, IHC (p) - ABIN4365682 : Chakraborty, Kumar, Mishra, Patil, Kundu: Semaphorin 3A suppresses tumor growth and metastasis in mice melanoma model. in PLoS ONE 2012 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal VWF Primary Antibody for IHC, ELISA - ABIN1585505 : Wang, Fan, Yu, Liao, Zhao, Mandeville, Guo, Lo, Wang: Effects of tissue plasminogen activator and annexin A2 combination therapy on long-term neurological outcomes of rat focal embolic stroke. in Stroke; a journal of cerebral circulation 2014 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal VWF Primary Antibody for ID, IHC (fro) - ABIN2477117 : Clark, Plotnick, Wessel, Zyna: Guidelines for the student with diabetes: a school policy. ADA Professional Affairs Subcommittee. in The Diabetes educator 1993 (PubMed)
    Show all 4 Pubmed References

  6. Human Polyclonal VWF Primary Antibody for IHC (fro), FACS - ABIN2477119 : De Meyer, Hoylaerts, Kockx, Yamamoto, Herman, Bult: Intimal deposition of functional von Willebrand factor in atherogenesis. in Arteriosclerosis, thrombosis, and vascular biology 1999 (PubMed)
    Show all 4 Pubmed References

  7. All Species Monoclonal VWF Primary Antibody for ELISA, WB - ABIN316380 : Sen, Tyagi, Patibandla, Dean, Tyagi, Roberts, Lominadze: Fibrinogen-induced endothelin-1 production from endothelial cells. in American journal of physiology. Cell physiology 2009 (PubMed)

  8. Human Polyclonal VWF Primary Antibody for IF (cc), IF (p) - ABIN670506 : Du, Wang, Zhao, Li, Kong, Yang, Zhang: Gradient nanofibrous chitosan/poly ?-caprolactone scaffolds as extracellular microenvironments for vascular tissue engineering. in Biomaterials 2011 (PubMed)

  9. Human Polyclonal VWF Primary Antibody for ICC, IHC (fro) - ABIN268106 : Shi, Neoh, Kang, Poh, Wang: Enhanced endothelial differentiation of adipose-derived stem cells by substrate nanotopography. in Journal of tissue engineering and regenerative medicine 2014 (PubMed)

  10. Human Monoclonal VWF Primary Antibody for IHC (fro) - ABIN2689964 : Sadler: von Willebrand factor. in The Journal of biological chemistry 1992 (PubMed)

More Antibodies against VWF Interaction Partners

Human Von Willebrand Factor (VWF) interaction partners

  1. Data suggest that an aspartate at position 1261 is the most critical residue of VWF N-terminal linker for inhibiting binding of VWF A1 domain to GP1BA (show GP1BA Antibodies) on platelets in a model simulating blood flow velocity; network of salt bridges between Asp1261 and rest of VWF A1 domain lock N-terminal linker in place such that binding to GP1BA (show GP1BA Antibodies) is reduced.

  2. In people with dysglycaemia and other cardiovascular risk factors, basal insulin (show INS Antibodies) does not improve the levels of markers of fibrinolysis or von Willebrand factor compared to standard glucose-lowering treatments.

  3. low VWF levels can be associated with significant bleeding and are predominantly due to reductions in VWF synthesis and/or constitutive secretion.

  4. Refrigeration-induced binding of VWF to platelets facilitates their rapid clearance by inducing GPIbalpha (show GP1BA Antibodies)-mediated signaling.

  5. Data show that von Willebrand factor (VWF) is first converted from a compact to linear form by flow, and is subsequently activated to bind platelet glycoprotein Ib alpha polypeptide (show ITGAE Antibodies) (GPIbalpha (show GP1BA Antibodies)) in a tension-dependent manner.

  6. The >30 nm macroglycopeptide separating the two domains of GPIbalpha (show GP1BA Antibodies) transmits force on the VWF-GPIbalpha (show GP1BA Antibodies) bond (whose lifetime is prolonged by leucine-rich repeat domain unfolding) to the juxtamembrane mechanosensitive domain to enhance its unfolding, resulting in unfolding cooperativity at an optimal force.

  7. von Willebrand factor processing and function has been summarized using various biophysical techniques. (Review)

  8. Soluble VWF was statistically elevated in major depressive disorder.

  9. Rare genetic variants in the ADAMTS13 (show ADAMTS13 Antibodies) on Willebrand factor-binding domain contribute to pediatric stroke.

  10. results indicate that VWF multimer accumulation on endothelium, as occurs in congenital thrombotic thrombocytopenic purpura, promotes the activation of the complement alternative pathway that proceeds until C5 cleavage with the formation of C5a and the terminal C5b-9 complex

Pig (Porcine) Von Willebrand Factor (VWF) interaction partners

  1. alterations in glycosylation of vWF and other adhesion proteins associated with the targeting of the alpha1,3-Gal (show GAL Antibodies)-epitope in mutant swine may have salutatory effects on the primate platelet activation observed in these xenografts.

Cow (Bovine) Von Willebrand Factor (VWF) interaction partners

  1. Hemodynamic activation of vWF and increased plasma ADAMTS-13 (show ADAMTS13 Antibodies) may have contributed to reduced high-molecular-weight vWF multimers and impairment of the vWF-platelet aggregation pathway during mechanical circulatory support.

  2. both the gpIb-VWF interaction and the integrin alpha(2 (show ITGA2 Antibodies))beta(1)-collagen interaction contribute to platelet adhesion under high shear stress; integrin alpha(II (show GSTA3 Antibodies))beta(1) makes a greater contribution to adhesion to type I collagen because less VWF is bound

Mouse (Murine) Von Willebrand Factor (VWF) interaction partners

  1. Refrigeration-induced binding of VWF to platelets facilitates their rapid clearance by inducing GPIbalpha (show GP1BA Antibodies)-mediated signaling.

  2. BLOC-2 (show HPS6 Antibodies) subunit HPS6 (show HPS6 Antibodies) deficiency affects the tubulation and secretion of von Willebrand factor from mouse endothelial cells

  3. A novel single-domain antibody against von Willebrand factor A1 domain that interferes with VWF-platelet interactions in vivo. By using this sdAb, show that the A1 domain is pertinent to the participation of VWF in the inflammatory response.

  4. These experiments delineate an unexpected pathway in which microbiota-triggered TLR2 (show TLR2 Antibodies) signaling alters the synthesis of proadhesive VWF by the liver endothelium and favors platelet integrin-dependent thrombus growth.

  5. ADAMTS13 (show ADAMTS13 Antibodies) controls vascular remodeling by modifying VWF reactivity during stroke recovery.

  6. these novel findings support the hypothesis that conformation of the VWF A domains plays a critical role in modulating macrophage-mediated clearance of VWF in vivo.

  7. results revealed localized vascular expression of FVIII (show F8 Antibodies) and von Willebrand factor and identified lymphatic endothelial cell as a major cellular source of FVIII (show F8 Antibodies) in extrahepatic tissues.

  8. Endothelial cell derivedVWF is the major determinant that mediates VWF-dependent ischemic stroke by promoting postischemic thrombo-inflammation.

  9. VWF deficiency reduces the progression of liver fibrosis, suggesting a mechanistic role of elevated plasma VWF levels in cirrhosis

  10. von Willebrand factor exerts beneficial effects in a mouse sepsis model via recruitment of neutrophils to inflammatory sites.

VWF Antigen Profile

Protein Summary

The glycoprotein encoded by this gene functions as both an antihemophilic factor carrier and a platelet-vessel wall mediator in the blood coagulation system. It is crucial to the hemostasis process. Mutations in this gene or deficiencies in this protein result in von Willebrand's disease. An unprocessed pseudogene has been found on chromosome 22.

Gene names and symbols associated with VWF

  • von Willebrand factor (VWF) antibody
  • von Willebrand factor (vwf) antibody
  • von Willebrand factor (Vwf) antibody
  • Von Willebrand factor (Vwf) antibody
  • 6820430P06Rik antibody
  • AI551257 antibody
  • B130011O06Rik antibody
  • C630030D09 antibody
  • F8VWF antibody
  • si:ch1073-474e24.1 antibody
  • VWD antibody
  • VWF antibody

Protein level used designations for VWF

von Willebrand factor , coagulation factor VIII VWF

GENE ID SPECIES
451773 Pan troglodytes
493760 Felis catus
570643 Danio rerio
619381 Monodelphis domestica
722019 Macaca mulatta
7450 Homo sapiens
116669 Rattus norvegicus
399544 Canis lupus familiaris
100009165 Oryctolagus cuniculus
399543 Sus scrofa
280958 Bos taurus
100732530 Cavia porcellus
419031 Gallus gallus
101110931 Ovis aries
22371 Mus musculus
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