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Acts as a nucleation-promoting factor (NPF) that stimulates Arp2/3-mediated actin polymerization both at the Golgi apparatus and along tubular membranes (By similarity). Additionally we are shipping WHAMM Antibodies (4) and many more products for this protein.
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WHAMM directs the Arp2/3 complex to the endoplasmic reticulum for autophagosome biogenesis through an actin comet tail mechanism.
Data show that RhoD binds the actin nucleation-promoting factor WHAMM (WASp homologue associated with actin Golgi membranes and microtubules), as well as the related filamin A-binding protein FILIP1.
results give rise to a model whereby distinct MT-bound and actin-nucleating populations of WHAMM collaborate during membrane tubulation
data suggest that WHAMM is required for peripheral spindle migration and asymmetric cytokinesis during mouse oocyte maturation
Acts as a nucleation-promoting factor (NPF) that stimulates Arp2/3-mediated actin polymerization both at the Golgi apparatus and along tubular membranes (By similarity). Involved as a regulator of Golgi positioning and morphology (By similarity). Participates in vesicle transport between the reticulum endoplasmic and the Golgi complex.
WAS protein homology region 2 domain-containing protein 1
, WASP homolog-associated protein with actin, membranes and microtubules
, WH2 domain-containing protein 1
, WAS protein homology region 2 domain containing 1