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WD Repeat Domain, Phosphoinositide Interacting 2 Proteins (WIPI2)

WD40 repeat proteins are key components of many essential biologic functions. Additionally we are shipping WIPI2 Antibodies (56) and WIPI2 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
WIPI2 26100 Q9Y4P8
Mouse WIPI2 WIPI2 74781 Q80W47
Rat WIPI2 WIPI2 288498 Q6AY57
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Top WIPI2 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$3,215.67
Details
Yeast Yeast His tag   1 mg Log in to see 56 to 66 Days
$3,406.33
Details

WIPI2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,

More Proteins for WD Repeat Domain, Phosphoinositide Interacting 2 (WIPI2) Interaction Partners

Human WD Repeat Domain, Phosphoinositide Interacting 2 (WIPI2) interaction partners

  1. The specific autophagosomal localization of both WIPI1 (show WIPI1 Proteins) and WIPI2 (refered to as WIPI puncta) has been employed to assess autophagy using fluorescence microscopy methods, such as confocal and live-cell video microscopy

  2. Data suggest WIPI1/WIPI2 (show WIPI1 Proteins) co-localize with microtubule-associated light chain 3 and autophagy related proteins 2/14L, participate in biogenesis of phagosomes, autophagy, and mobilization of lipids to/from intracellular droplets. [review-like article]

  3. WIPI-1 (show WIPI1 Proteins) and WIPI-2 are functionally required in mediating the PI3P signal at the onset of autophagy in NB4 cells.

  4. Data suggest that WIPI2b directly interacts with dimer of ATG16L1 (autophagy related 16-like 1 (show ATG16L1 Proteins)) and this interaction is linked to production of phosphatidylinositol 3-phosphate in endoplasmic reticulum triggered by autophagosome formation. [REVIEW]

  5. WIPI2b binds the membrane surrounding Salmonella and recruits the Atg12 (show ATG12 Proteins)-5-16L1 complex, initiating LC3 (show MAP1LC3A Proteins) conjugation, autophagosomal membrane formation, and engulfment of Salmonella.

  6. WIPI2 is a phosphatidylinsitol-3-phosphate binding protein required for starvation induced autophagy.

  7. Freeze-fracture replica immunolabelling reveals WD-repeat protein (show DCAF7 Proteins) interacting with phosphoinositides 1 and 2 (WIPI-1 (show WIPI1 Proteins) and WIPI-2) as membrane components of autophagosomes and the plasma membrane (PM).

WIPI2 Protein Profile

Protein Summary

WD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. Members of the WIPI subfamily of WD40 repeat proteins, such as WIPI2, have a 7-bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas-Cezanne et al., 2004

Gene names and symbols associated with WIPI2

  • WD repeat domain phosphoinositide-interacting protein 2 (wipi2)
  • WD repeat domain, phosphoinositide interacting 2 (WIPI2)
  • WD repeat domain, phosphoinositide interacting 2 (Wipi2)
  • 1110018O08Rik protein
  • 2510001I10Rik protein
  • ATG18B protein
  • Atg21 protein
  • WIPI-2 protein

Protein level used designations for WIPI2

WIPI-2 , WD repeat domain phosphoinositide-interacting protein 2 , WD40 repeat protein interacting with phosphoinositides 2 , WIPI49-like protein 2

GENE ID SPECIES
380011 Xenopus laevis
26100 Homo sapiens
74781 Mus musculus
288498 Rattus norvegicus
416481 Gallus gallus
Selected quality suppliers for WIPI2 Proteins (WIPI2)
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