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WD Repeat Domain 36 Proteins (WDR36)

WDR36 encodes a member of the WD repeat protein family. Additionally we are shipping WD Repeat Domain 36 Antibodies (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse WDR36 WDR36 225348  
WDR36 134430 Q8NI36
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Top WD Repeat Domain 36 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

WDR36 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for WD Repeat Domain 36 (WDR36) Interaction Partners

Mouse (Murine) WD Repeat Domain 36 (WDR36) interaction partners

  1. Our data obtained in Wdr36(+/-) mice do not support the assumption of a causative role for WDR36 in the pathogenesis of primary open-angle glaucoma.

  2. results provide evidence that WDR36 is an essential protein in mammalian cells which is involved in the nucleolar processing of small subunit 18S rRNA

  3. WDR36 plays an important functional role in the retina homeostasis and mutation to this gene can cause devastating retinal damage.

Zebrafish WD Repeat Domain 36 (WDR36) interaction partners

  1. Loss of Wdr36 function leads to an activation of the p53 (show TP53 Proteins) stress-response pathway, suggesting that defects in p53 (show TP53 Proteins) pathway may influence the impact of WDR36 variants on primary open-angle glaucoma.

Human WD Repeat Domain 36 (WDR36) interaction partners

  1. According to molecular genetic studies, WDR36 causative gene involved in the development of Primary open-angle glaucoma.

  2. Single nucleotide polymorphism in the WDR36 gene, rs10038177 (c.710+30C>T), was found to be strongly associated with the high tension glaucoma cases, but not with controls in the East Indian population.

  3. Rare WDR36 variants and the P53 (show TP53 Proteins) p.R72P polymorphism behaved as moderate glaucoma risk factors in Spanish patients. The authors provide evidence for a genetic interaction between WDR36 and P53 (show TP53 Proteins) variants in glaucoma susceptibility.

  4. WDR36 acts as a scaffold protein (show HOMER1 Proteins) tethering a G-protein-coupled receptor (show ADRA1A Proteins), Galphaq (show GNAQ Proteins) and phospholipase C beta 2 (show PLCb2 Proteins) in a signalling complex

  5. WDR36 sequence variance was only a rare cause of primary open-angel glaucoma glaucoma in Italian families with glaucoma.

  6. Genetic variants of CYP1B1 (show CYP1B1 Proteins) and WDR36 in the patients with primary congenital glaucoma and primary open angle glaucoma from Saint-Petersburg

  7. First series of WDR36 mutations in subjects with high- and low-pressure adult-onset primary open angle glaucoma. First mRNA expression profiling of this gene in various ocular and non-ocular tissues for human and mouse.

  8. Our results provided mapping of a novel locus for juvenile-onset primary open angle glaucoma at 5q and excluded coding or splicing junctions mutations within the WDR36 gene.

  9. The association of WDR36 sequence variants with more severe disease in affected individuals suggests that defects in the WDR36 gene can contribute to POAG and that WDR36 may be a glaucoma modifier gene.

  10. The WDR36 D658G is a neutral variant in the Australian population.

WD Repeat Domain 36 (WDR36) Protein Profile

Protein Summary

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Mutations in this gene have been associated with adult-onset primary open-angle glaucoma (POAG).

Gene names and symbols associated with WD Repeat Domain 36 Proteins (WDR36)

  • WD repeat domain 36 (Wdr36)
  • WD repeat domain 36 (wdr36)
  • WD repeat domain 36 (WDR36)
  • WD repeat-containing protein 36 (PGTG_10670)
  • 5730444A13Rik protein
  • GLC1G protein
  • TA-WDRP protein
  • TAWDRP protein
  • UTP21 protein
  • wu:fb33e10 protein
  • zgc:66324 protein

Protein level used designations for WD Repeat Domain 36 Proteins (WDR36)

WD repeat-containing protein 36 , T-cell activation WD repeat protein , T-cell activation WD repeat-containing protein

GENE ID SPECIES
225348 Mus musculus
321745 Danio rerio
415609 Gallus gallus
10545636 Puccinia graminis f. sp. tritici CRL 75-36-700-3
134430 Homo sapiens
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