anti-WD Repeat Domain 5 (WDR5) Antibodies

WDR5 encodes a member of the WD repeat protein family. Additionally we are shipping WDR5 Proteins (13) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
WDR5 11091 P61964
WDR5 140858 P61965
WDR5 362093 Q498M4
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Top anti-WDR5 Antibodies at antibodies-online.com

Showing 10 out of 99 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IP, IHC, WB <b>WB Suggested Anti-WDR5 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>721_B cell lysate WB Suggested Anti-WDR5 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500 <br /> Positive Control:.21_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Wdr5 AntibodyTitration: 1.0 µg/mL <br /> Positive Control: Mouse Pancreas 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB WDR5 Antibody (N-term) western blot analysis in A2058 cell line lysates (35 µg/lane). This demonstrates the WDR5 antibody detected the WDR5 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to WDR5 on HeLa cell (antibody concentration 10 µg/mL). WDR5 monoclonal antibody (M01), clone 2C2. Western Blot analysis of WDR5 expression in A-549. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated ELISA, WB Figure 1: Western blot analysis using WDR5 mouse mAb against Hela (1) cell lysate. 100 μL Log in to see 2 to 3 Days
$393.80
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Mouse Rabbit Un-conjugated ELISA, WB 50 μL Log in to see 2 to 3 Days
$185.00
Details
Human Rabbit Un-conjugated WB WDR5 Antibody (N-term)  western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the WDR5 antibody detected the WDR5 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IF, WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details

WDR5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus) ,
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Top referenced anti-WDR5 Antibodies

  1. Human Monoclonal WDR5 Primary Antibody for ELISA, WB - ABIN969456 : Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007 (PubMed)
    Show all 2 Pubmed References

More Antibodies against WDR5 Interaction Partners

Xenopus laevis WD Repeat Domain 5 (WDR5) interaction partners

  1. The WDR5 is essential for vertebrate development, in that WDR5-depleted X. laevis tadpoles exhibit a variety of developmental defects and abnormal spatial Hox (show MSH2 Antibodies) gene expression.

Human WD Repeat Domain 5 (WDR5) interaction partners

  1. WDR5 functions to sustain proper execution of DNA replication in pancreatic ductal adenocarcinoma cells, as previously suggested by replication stress studies involving MLL1, and c-Myc (show MYC Antibodies), also found to interact with WDR5.

  2. This report documents a novel lncRNA, GClnc1, which may act as a scaffold to recruit the WDR5 and KAT2A (show KAT2A Antibodies) complex and modify the transcription of target genes. This study reveals that GClnc1 is an oncogenic lncRNA in human gastric cancer.

  3. WDR5 shows a direct binding to the ZNF407 (show ZNF407 Antibodies) promoter.

  4. Taken together, these data suggest that WDR5 is directly involved in p53 (show TP53 Antibodies) signaling pathway. Our studies provide a new insight into WDR5 functions in A549 cells.

  5. Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (show CAPS Antibodies) (WDR5) and Mixed Lineage Leukemia (MLL (show MLL Antibodies))/SET1 (show SETD1A Antibodies) Family Proteins Specifically Inhibits MLL1 and SETd1A (show SETD1A Antibodies) Methyltransferase Complexes.

  6. WDR5 over-expression is associated with poor breast cancer clinical outcome.

  7. Results identify WDR5 as a key cofactor for N-Myc (show MYCN Antibodies)-regulated transcriptional activation and tumorigenesis and as a novel therapeutic target for MYCN (show MYCN Antibodies)-amplified neuroblastomas.

  8. BIG3 may block the KPNAs (KPNA1 (show KPNA1 Antibodies), KPNA5 (show KPNA5 Antibodies), and KPNA6 (show KPNA6 Antibodies)) binding region(s) of PHB2 (show PHB2 Antibodies).

  9. solution structures of the MLL3 core complex assembled with and without WDR5 by small angle x-ray scattering show similar overall topologies

  10. Target gene recognition by MYC (show MYC Antibodies) depends on its interaction with WDR5. This interaction could create an avidity-based chromatin recognition mechanism allowing MYC (show MYC Antibodies) to select its target genes in response to both genetic and epigenetic determinants. Review.

Mouse (Murine) WD Repeat Domain 5 (WDR5) interaction partners

  1. Wdr5 suppression also reduced IFNgamma, Il-1beta (show IL1B Antibodies), and TNFalpha (show TNF Antibodies) induced chemokine (show CCL1 Antibodies) gene expression in b-cells without affecting islet-cell survival or b-cell function after 48hrs, but did begin to increase islet-cell apoptosis

  2. results suggest that specific RNAs are integral inputs into the WDR5-MLL (show MLL Antibodies) complex for maintenance of the active chromatin state and embryonic stem cell fates

  3. Data show that broad association of myc proto-oncogene protein MYC (show MYC Antibodies) with chromatin depends on interaction with the WD40 (show DCAF12L2 Antibodies)-repeat protein WDR5.

  4. BIG3 inhibits insulin (show INS Antibodies) granule biogenesis and insulin (show INS Antibodies) secretion.

  5. BIG3 negatively regulates insulin (show INS Antibodies) granule exocytosis by restricting insulin (show INS Antibodies) granule biogenesis without the release kinetics of individual granules at the final exocytotic steps being affected.

  6. Depletion of KAT2B (show KAT2B Antibodies) or WDR5 decreased gluconeogenic gene expression.

  7. analysis of a novel mechanism for epigenetic control of SMC (show DYM Antibodies)-marker gene expression during development through interaction of WDR5, homeodomain proteins, and chromatin remodeling enzymes

  8. Study shows that WD repeat domain 5 (Wdr5), a core member of the mammalian Trithorax (show MLLT1 Antibodies) (trxG) complex, positively correlates with the undifferentiated state and is a regulator of ES cell self-renewal.

  9. Characterization of a novel WDR5-binding site that recruits RbBP5 (show RBBP5 Antibodies) through a conserved motif to enhance methylation of histone H3 (show HIST3H3 Antibodies) lysine 4 by mixed lineage leukemia protein-1.

  10. WDR5 is essential in assembling a virus-induced VISA (show MAVS Antibodies)-associated complex and plays an important role in virus-triggered induction of type I interferons.

WDR5 Antigen Profile

Protein Summary

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified.

Gene names and symbols associated with WDR5

  • WD repeat domain 5 (wdr5) antibody
  • WD repeat domain 5 L homeolog (wdr5.L) antibody
  • WD repeat domain 5 S homeolog (wdr5.S) antibody
  • WD repeat domain 5 (WDR5) antibody
  • WD repeat domain 5 (Wdr5) antibody
  • 2410008O07Rik antibody
  • AA408785 antibody
  • AA960360 antibody
  • Big antibody
  • Big-3 antibody
  • MGC80538 antibody
  • MGC81485 antibody
  • SWD3 antibody
  • wdr5-a antibody
  • wdr5-b antibody
  • wu:fk47f04 antibody
  • xwdr5 antibody
  • zgc:56591 antibody
  • zgc:76895 antibody

Protein level used designations for WDR5

WD repeat domain 5 , WD repeat-containing protein 5 , BMP2-induced 3-kb gene protein , SWD3, Set1c WD40 repeat protein, homolog , WD-repeat protein 5 , WD repeat-containing protein BIG-3

GENE ID SPECIES
406372 Danio rerio
446809 Xenopus laevis
447447 Xenopus laevis
496891 Xenopus (Silurana) tropicalis
11091 Homo sapiens
140858 Mus musculus
362093 Rattus norvegicus
100125836 Bos taurus
Selected quality suppliers for anti-WDR5 (WDR5) Antibodies
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