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WD Repeat Domain 62 (WDR62) ELISA Kits

WDR62 is proposed to play a role in cerebral cortical development. Additionally we are shipping WDR62 Antibodies (3) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat WDR62 WDR62 308492  
Anti-Human WDR62 WDR62 284403 O43379
Anti-Mouse WDR62 WDR62 233064  
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More ELISA Kits for WDR62 Interaction Partners

Human WD Repeat Domain 62 (WDR62) interaction partners

  1. Data show that CUL4B (show CUL4B ELISA Kits) variants are associated with a wide range of cerebral malformations and suggest an important role in brain through its interaction with WDR62, a protein in which variants were identified in patients with cerebral malformations.

  2. Genetic factors contribute to modify the severity of the WDR62 phenotype.

  3. WDR62 controls neurogenesis through JNK (show MAPK8 ELISA Kits) signaling in rat model.

  4. Abnormal centrosome and spindle morphology in a patient with autosomal recessive primary microcephaly type 2 due to compound heterozygous WDR62 gene mutation

  5. WDR62 may be a novel prognostic marker and a potential chemotherapy target for gastric cancer.

  6. A homozygous deletion mutation c.1143delA was detected in exon 9 of WDR62 gene, in all affected individuals with primary microcephaly in a Pakistani family, which resulted in frameshift and protein truncation (p.H381PfsX48).

  7. Data indicate that WDR62 dimerization is required for JNK2 (show MAPK9 ELISA Kits) and MKK7beta1 recruitment.

  8. homozygous missense mutation in WDR62, p.E400K, was found in both boys and segregated with the condition in this family. WDR62 is one of seven genes responsible for autosomal recessive primary microcephaly

  9. Homozygous mutations in WDR62 cause autosomal recessive primary microcephaly in families linked to the MCPH2 locus. This gene encodes a centrosomal as well as nuclear protein (show RDBP ELISA Kits).

  10. study reports using whole-exome sequencing to identify compound heterozygous mutations in the WD repeat domain 62 (WDR62) gene as the cause of recurrent polymicrogyria in a sibling pair

Mouse (Murine) WD Repeat Domain 62 (WDR62) interaction partners

  1. Wdr62 interacts with Aurora A (show AURKA ELISA Kits) to control mitotic progression, and loss of these interactions leads to mitotic delay and cell death of NPCs, which could be a potential cause of human microcephaly.

  2. A key role for WDR62 in metaphase spindle organization, required for normal mitotic progression.

  3. In mice and humans, WDR62 transcripts and protein are enriched in neural progenitors within the ventricular and subventricular zones.

WDR62 Antigen Profile

Antigen Summary

This gene is proposed to play a role in cerebral cortical development. Mutations in this gene have been associated with microencephaly, cortical malformations, and mental retardation. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with WD Repeat Domain 62 (WDR62) ELISA Kits

  • WD repeat domain 62 (Wdr62) antibody
  • WD repeat domain 62 (WDR62) antibody
  • si:ch211-152c12.2 (si:ch211-152c12.2) antibody
  • WD repeat domain 62 (LOC100348948) antibody
  • 2310038K02Rik antibody
  • C19orf14 antibody
  • MCPH2 antibody
  • MGC195119 antibody
  • RGD1306714 antibody
  • wu:fa11h05 antibody
  • wu:fb33e12 antibody

Protein level used designations for WD Repeat Domain 62 (WDR62) ELISA Kits

WD repeat-containing protein 62 , WD repeat domain 62 , WD repeat domain 62-like , si:ch211-152c12.2 , fb33e12 , WD repeat-containing protein 62-like , microcephaly, primary autosomal recessive 2

GENE ID SPECIES
308492 Rattus norvegicus
455973 Pan troglodytes
484565 Canis lupus familiaris
530449 Bos taurus
570949 Danio rerio
100016939 Monodelphis domestica
100348948 Oryctolagus cuniculus
100410800 Callithrix jacchus
284403 Homo sapiens
233064 Mus musculus
100144885 Sus scrofa
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