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WD Repeat Domain 77 (WDR77) ELISA Kits

WDR77 is a component of the 20S PRMT5 (MIM 604045)-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins (see MIM 601061). Additionally we are shipping WD Repeat Domain 77 Antibodies (49) and WD Repeat Domain 77 Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
WDR77 79084 Q9BQA1
WDR77 70465 Q99J09
WDR77 310769 Q4QR85
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Top WD Repeat Domain 77 ELISA Kits at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human
96 Tests Log in to see 11 to 13 Days
$875.60
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Mouse
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$875.60
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Rat
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$875.60
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Cow
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$1,029.60
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More ELISA Kits for WD Repeat Domain 77 Interaction Partners

Xenopus laevis WD Repeat Domain 77 (WDR77) interaction partners

  1. Data indicate that MEP50 WD repeat protein (show DCAF7 ELISA Kits) is essential for methylation of histones H4 and H2A (show H2AFX ELISA Kits) by PRMT5 (show PRMT5 ELISA Kits) arginine methyltransferase.

  2. Structure of MEP50/Wdr77 in the PRMT5 (show PRMT5 ELISA Kits)-MEP50 complex

  3. Protein arginine methyltransferase Prmt5 (show PRMT5 ELISA Kits)-Mep50 methylates histones H2A (show H2AFX ELISA Kits) and H4 and the histone chaperone nucleoplasmin (show NPM1 ELISA Kits) in Xenopus laevis eggs

Human WD Repeat Domain 77 (WDR77) interaction partners

  1. MEP50 genes reduces gene expression through histone arginine methylation in keratinocytes.

  2. MEP50 can transform cells independent of AR and ER.

  3. Data indicate that MEP50 WD repeat protein (show DCAF7 ELISA Kits) is essential for methylation of histones H4 and H2A by PRMT5 (show PRMT5 ELISA Kits) arginine methyltransferase.

  4. These findings characterize PKG (show PRKG1 ELISA Kits) as a novel regulator of AR-mediated transcription by enhancing AR cofactor p44/WDR77's function.

  5. Data indicate a transcription complex androgen receptor (AR (show AR ELISA Kits))-p44 (show GTF2H2 ELISA Kits)-Smad1 (show GARS ELISA Kits), and confirmed for physical interaction by co-immunoprecipitaion.

  6. These studies suggest a novel mechanism by which proliferation and differentiation of prostate epithelial cells are controlled by WDR77's location in the cell.

  7. structure of the surprising hetero-octameric complex reveals the close interaction between the seven-bladed beta-propeller MEP50 and the N-terminal domain of PRMT5 (show PRMT5 ELISA Kits), and delineates the structural elements of substrate recognition.

  8. p44 plays a role in mediating the effects of hormones during ovarian tumorigenesis.

  9. expression and function of p44 in breast cancer; expression of p44 shows strong cytoplasmic expression in morphologically normal terminal ductal lobular units, while nuclear p44 is observed in both ductal carcinoma in situ and invasive carcinoma

  10. Here, we describe a novel component of the methylosome, a 50-kilodalton WD repeat protein (show DCAF7 ELISA Kits) termed methylosome protein 50 (MEP50).

Mouse (Murine) WD Repeat Domain 77 (WDR77) interaction partners

  1. These findings characterize PKG (show PRKG1 ELISA Kits) as a novel regulator of AR-mediated transcription by enhancing AR cofactor p44/WDR77's function.

  2. Silencing p21(Cip1 (show CDKN1A ELISA Kits)) or NF-kappaB (show NFKB1 ELISA Kits) p65 (show NFkBP65 ELISA Kits) expression with short hairpin RNA (shRNA) abolished astrocyte activation and rescued the astrocyte growth inhibition induced by deletion of the p44/WDR77 gene.

WD Repeat Domain 77 (WDR77) Antigen Profile

Antigen Summary

WDR77 is a component of the 20S PRMT5 (MIM 604045)-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins (see MIM 601061). This modification targets Sm proteins to the survival of motor neurons (SMN) complex (see MIM 600354) for assembly into small nuclear ribonucleoprotein core particles (Friesen et al., 2002

Gene names and symbols associated with WD Repeat Domain 77 (WDR77) ELISA Kits

  • WD repeat domain 77 (wdr77) antibody
  • WD repeat domain 77 (WDR77) antibody
  • WD repeat domain 77 (LOC100352088) antibody
  • WD repeat domain 77 (LOC100357980) antibody
  • WD repeat domain 77 (Wdr77) antibody
  • 2610003I18Rik antibody
  • 2610312E17Rik antibody
  • C79984 antibody
  • MEP-50 antibody
  • MEP50 antibody
  • Nbla10071 antibody
  • p44 antibody
  • p44/MEP50 antibody
  • RGD1310479 antibody
  • RP11-552M11.3 antibody
  • valois antibody
  • WDR77 antibody

Protein level used designations for WD Repeat Domain 77 (WDR77) ELISA Kits

WD repeat-containing protein 77 , methylosome protein 50 , WD repeat domain 77 , methylosome protein 50-like , androgen receptor cofactor p44 , MEP-50 , Ac2-269

GENE ID SPECIES
414664 Xenopus laevis
419865 Gallus gallus
677686 Macaca mulatta
100144971 Xenopus (Silurana) tropicalis
100352088 Oryctolagus cuniculus
100357980 Oryctolagus cuniculus
100391473 Callithrix jacchus
100614591 Pan troglodytes
79084 Homo sapiens
100172304 Pongo abelii
479902 Canis lupus familiaris
512993 Bos taurus
70465 Mus musculus
310769 Rattus norvegicus
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