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WDR8 encodes a member of the WD repeat protein family. Additionally we are shipping WD Repeat Domain 8 Antibodies (7) and WD Repeat Domain 8 Kits (2) and many more products for this protein.
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Cep135 is required for the recruitment of WDR8 to centrioles.
Knockdown of Wdr8 or hMsd1/SSX2IP (show SSX2IP Proteins) displayed very similar mitotic defects, in which spindle microtubules became shortened and misoriented.
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Studies of the related mouse protein suggest that the encoded protein may play a role in the process of ossification.
WD repeat-containing protein 8
, WD repeat domain 8
, WD repeat-containing protein WRAP73
, WD repeat-containing protein 8-like
, WD repeat-containing protein antisense to TP73