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wdr83 encodes a member of the WD-40 protein family. Additionally we are shipping WD Repeat Domain 83 Proteins (7) and many more products for this protein.
Showing 10 out of 62 products:
Human Polyclonal wdr83 Primary Antibody for EIA, WB - ABIN953483
Haase, Keiner, Mawrin, Wolf: Reduced Morg1 expression in ischemic human brain. in Neuroscience letters 2009
Show all 3 references for ABIN953483
Human Monoclonal wdr83 Primary Antibody for IF, ELISA - ABIN529646
Stahr, Frahm, Kretz, Bondeva, Witte, Wolf: Morg1(+/-) heterozygous mice are protected from experimentally induced focal cerebral ischemia. in Brain research 2012
Morg1 facilitates Par6 (show PARD6A Antibodies)-aPKC binding to Crb3 (show CRB3 Antibodies) for definition of apical identity of epithelial cells.
WDR83 and DHPS (show DHPS Antibodies) were capable of forming an RNA duplex at overlapping 3' untranslated regions and this duplex increased their mutual stability, which was required for the bidirectional regulation.
Component of a modular scaffold system that participates in the regulation of agonist-specific ERK (show EPHB2 Antibodies) signaling.
Morg1 expression is reduced in human brain tissue with ischemic damage. Reactive astrocytes in the surrounding brain tissue showed strong Morg1 expression.
this study shows for the first time in various renal cells that ANG II (show AGT Antibodies) modulates Morg1 expression and HIF-1alpha (show HIF1A Antibodies) transcriptional activity via cell type-specific mechanisms, demonstrating a novel mechanism by which ANG II (show AGT Antibodies) may contribute to renal disease.
The major finding of this study is that Morg1+/- mice are partially protected from cerebral ischemia and reperfusion injury in comparison to the WT (Morg1+/+) animals
Morg1 may be a novel therapeutic target to limit renal injury after ischemia-reperfusion
This gene encodes a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in multiple transcript variants.
MAPK organizer 1
, WD repeat domain-containing protein 83
, mitogen-activated protein kinase organizer 1
, WD repeat protein Morg1
, MAPK cascade scaffold protein