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anti-WNK Lysine Deficient Protein Kinase 3 (WNK3) Antibodies

WNK3 encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
WNK3 100363278  
WNK3 65267 Q9BYP7
WNK3 279561 Q80XP9
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Top anti-WNK3 Antibodies at antibodies-online.com

Showing 10 out of 62 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB PRKWNK3 Antibody (ABIN391067) western blot analysis in UM cell line lysates (35 µg/lane).This demonstrates the PRKWNK3 antibody detected the PRKWNK3 protein (arrow). WNK3(PRKWNK3) Antibody (C-term) (ABIN391067)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-WNK3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:2500Positive Control: ACHN cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin-embedded : human colon carcinoma labeled with Rabbit Anti-WNK3 protein Polyclonal Antibody (ABIN675713), Unconjugated 1:200 followed by conjugation to the secondary antibody Formalin-fixed and paraffin-embedded : human colon carcinoma labeled with Rabbit Anti-WNK3 protein Polyclonal Antibody (ABIN675713), Unconjugated 1:200 followed by conjugation to the secondary antibody 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated WB WNK3 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged WNK3 is approximately 0.03ng/ml as a capture antibody. Western Blot detection against Immunogen (36.74 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit APC IHC, ELISA   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

WNK3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-WNK3 Antibodies

  1. Human Polyclonal WNK3 Primary Antibody for IHC (p), WB - ABIN391067 : Veríssimo, Jordan: WNK kinases, a novel protein kinase subfamily in multi-cellular organisms. in Oncogene 2001 (PubMed)

More Antibodies against WNK3 Interaction Partners

Human WNK Lysine Deficient Protein Kinase 3 (WNK3) interaction partners

  1. WNK3 knockout mice exhibited significantly decreased infarct volume in a transgenic model of stroke and brain damage.

  2. There may be a novel role for WNK3 on the renal Na+-Cl-cotransporter (NCC (show SLC12A3 Antibodies)) expression at the plasma membrane, an effect apparently independent of the SPAK (show STK39 Antibodies) kinase and the aldosterone-SGK1 (show SGK1 Antibodies) pathway.

  3. LINGO-1 (show LINGO1 Antibodies) potentiates neuronal apoptosis, likely by inhibiting WNK3 kinase activity.

  4. WNK3 modulates intracellular Cl(-) concentration and regulatory volume decrease in HEK293 cells.

  5. The Wnk3 protein isoforms have a similar effect on SLC12 cotransporters. NKCC1 (show SLC12A2 Antibodies)/2 and NCC (show SLC12A3 Antibodies) were inhibited, even in hypertonicity, while KCCs were activated, even in isotonic conditions.

  6. Analysis of the data showed that WNK3 is an essential regulator of NKCC1 (show SLC12A2 Antibodies) and that WNK3 activates NKCC1 (show SLC12A2 Antibodies)-mediated ion transport necessary for cell volume changes associated with cell invasion.

  7. OXSR1 (show OXSR1 Antibodies) and WNK3 transcripts were substantially overexpressed in subjects with schizophrenia relative to comparison subjects.

  8. Data find that expression of the N termini of all four WNKs results in modest to strong activation of SGK1 (show SGK1 Antibodies).

  9. WNK3 lies within the critical linkage interval for several human monogenic disorders, including X-linked mental retardation. The function of mammalian WNK3 kinase remains to be investigated.

  10. WNK3 is involved in promoting cell survival by a mechanism at the level of procaspase-3 activation.

Mouse (Murine) WNK Lysine Deficient Protein Kinase 3 (WNK3) interaction partners

  1. angiotensin II activates the WNK-SPAK (show STK39 Antibodies)-NKCC1 (show SLC12A2 Antibodies) phosphorylation cascade through the angiotensin II type 1 receptor (show AGTR1 Antibodies). activation of the WNK-SPAK (show STK39 Antibodies)-NKCC1 (show SLC12A2 Antibodies) phosphorylation cascade induced by a low-salt diet and angiotensin II is dependent on WNK3.

  2. WNK3 may serve as a member of a kinase network that facilitates the fine-tuning of renal transepithelial NaCl transport.

  3. WNK3 increases the cytoplasmic localization of Fox-1 (show A2BP1 Antibodies), thereby suppressing Fox-1 (show A2BP1 Antibodies)-dependent mrna splicing.

  4. suggest that WNK3 is part of the Cl(-)/volume-sensing mechanism necessary for the maintenance of cell volume during osmotic stress and the dynamic modulation of GABA neurotransmission

  5. effects of WNK3 on these transporters and their coexpression in renal epithelia implicate WNK3 in NaCl, water, and blood pressure homeostasis, perhaps via signaling downstream of vasopressin (show AVP Antibodies)

  6. WNK3 is likely a component of one of the mechanisms that determines the balance between renal NaCl reabsorption and K+ secretion.

WNK3 Antigen Profile

Protein Summary

This gene encodes a protein belonging to the 'with no lysine' family of serine-threonine protein kinases. These family members lack the catalytic lysine in subdomain II, and instead have a conserved lysine in subdomain I. This family member functions as a positive regulator of the transcellular Ca2+ transport pathway, and it plays a role in the increase of cell survival in a caspase-3-dependent pathway. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with WNK3

  • wu:fc63h12 (wu:fc63h12) antibody
  • WNK lysine deficient protein kinase 3 (LOC100363278) antibody
  • WNK lysine deficient protein kinase 3 (WNK3) antibody
  • WNK lysine deficient protein kinase 3 (Wnk3) antibody
  • fc63h12 antibody
  • Prkwnk3 antibody
  • RGD1563131 antibody
  • Wnk3-ps antibody

Protein level used designations for WNK3

wu:fc63h12 , WNK lysine deficient protein kinase 3 , protein kinase with no lysine 3 , serine/threonine-protein kinase WNK3 , WNK lysine deficient protein kinase 3, pseudogene , protein kinase lysine-deficient 3

GENE ID SPECIES
325273 Danio rerio
100363278 Rattus norvegicus
65267 Homo sapiens
279561 Mus musculus
100337119 Bos taurus
317420 Rattus norvegicus
Selected quality suppliers for anti-WNK3 (WNK3) Antibodies
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