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anti-WNT1 Inducible Signaling Pathway Protein 2 (WISP2) Antibodies

WISP2 encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. Additionally we are shipping WISP2 Proteins (15) and WISP2 Kits (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
WISP2 8839 O76076
WISP2 22403 Q9Z0G4
WISP2 29576 Q9JHC6
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Top anti-WISP2 Antibodies at antibodies-online.com

Showing 10 out of 75 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-Wisp2 Ctr Pab (ABIN390188) in A549 cell lysate. Wisp2 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. WISP2 Antibody (Center) (ABIN390188)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$253.00
Details
Human Rabbit Un-conjugated IP, WB Immunoprecipitation of WISP2 transfected lysate using anti-WISP2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with WISP2 MaxPab mouse polyclonal antibody (B01) . WISP2 MaxPab rabbit polyclonal antibody. Western Blot analysis of WISP2 expression in mouse liver. 100 μL Log in to see 9 Days
$418.57
Details
Human Rabbit Un-conjugated WB Host: Rabbit  Target Name: WISP2  Antibody Dilution: 1.0 µg/mL  Sample Tissue: Human Placenta 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB   0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated EIA, IHC (p) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$566.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA Human Testis (formalin-fixed, paraffin-embedded) stained with WISP2 antibody ABIN214722 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Anti-WISP2 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN961598 concentration 5 ug/ml. 50 μg Log in to see 8 to 10 Days
$511.50
Details

WISP2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Mouse (Murine)


Rat (Rattus) ,


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Top referenced anti-WISP2 Antibodies

  1. Human Polyclonal WISP2 Primary Antibody for EIA, WB - ABIN358746 : Banerjee, Saxena, Sengupta, Tawfik, Mayo, Banerjee: WISP-2 gene in human breast cancer: estrogen and progesterone inducible expression and regulation of tumor cell proliferation. in Neoplasia (New York, N.Y.) 2003 (PubMed)
    Show all 5 references for ABIN358746

  2. Human Monoclonal WISP2 Primary Antibody for ELISA, WB - ABIN395930 : Pasmant, Ortonne, Rittié, Laurendeau, Lévy, Lazar, Parfait, Leroy, Dessen, Valeyrie-Allanore, Perbal, Wolkenstein, Vidaud, Vidaud, Bièche: Differential expression of CCN1/CYR61, CCN3/NOV, CCN4/WISP1, and CCN5/WISP2 in neurofibromatosis type 1 tumorigenesis. in Journal of neuropathology and experimental neurology 2009 (PubMed)
    Show all 5 references for ABIN395930

  3. Human Polyclonal WISP2 Primary Antibody for IHC (p), WB - ABIN390188 : Kumar, Hand, Connor, Dodds, Ryan, Trill, Fisher, Nuttall, Lipshutz, Zou, Hwang, Votta, James, Rieman, Gowen, Lee: Identification and cloning of a connective tissue growth factor-like cDNA from human osteoblasts encoding a novel regulator of osteoblast functions. in The Journal of biological chemistry 1999 (PubMed)
    Show all 3 references for ABIN390188

  4. Human Polyclonal WISP2 Primary Antibody for IP, WB - ABIN948739 : Conde, Scotece, Abella, Gómez, López, Villar, Hermida, Pino, Gómez-Reino, Gualillo: Identification of novel adipokines in the joint. Differential expression in healthy and osteoarthritis tissues. in PLoS ONE 2015 (PubMed)

  5. Human Polyclonal WISP2 Primary Antibody for WB - ABIN871768 : Pennica, Swanson, Welsh, Roy, Lawrence, Lee, Brush, Taneyhill, Deuel, Lew, Watanabe, Cohen, Melhem, Finley, Quirke, Goddard, Hillan, Gurney, Botstein, Levine: WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors. in Proceedings of the National Academy of Sciences of the United States of America 1999 (PubMed)

More Antibodies against WISP2 Interaction Partners

Zebrafish WNT1 Inducible Signaling Pathway Protein 2 (WISP2) interaction partners

  1. One paralog of mammalian wisp2 was found in zebrafish.

Human WNT1 Inducible Signaling Pathway Protein 2 (WISP2) interaction partners

  1. Studies indicate that the CYR61 (show CYR61 Antibodies) CTGF (show CTGF Antibodies) NOV (show NOV Antibodies) matricellular proteins (CCN family of proteins) comprises the members CCN1 (show CCNA2 Antibodies), CCN2 (show CTGF Antibodies), CCN3 (show NOV Antibodies), CCN4 (show WISP1 Antibodies), CCN5 and CCN6 (show WISP3 Antibodies) and have been identified in various types of cancer.

  2. Report opposing effects of CCN2 (show CTGF Antibodies) and CCN5 on fibroblast proliferation and transdifferentiation induced by TGF-beta (show TGFB1 Antibodies).

  3. Serum WISP2 correlated directly with fatty acid binding protein 4. Serum SFRP5 (show SFRP5 Antibodies) did not differ between obese (n=32) vs. nonobese (n=25) PCOS women, but reference women had lower SFRP5 (show SFRP5 Antibodies) (p<5x10(-6) as compared to both PCOS groups).

  4. Activation of CCN5 may have the therapeutic potential to kill triple-negative breast cancer.

  5. WISP2 has a role in regulating tumor cell susceptibility through EMT (show ITK Antibodies) by inducing the TGF-beta (show TGFB1 Antibodies) signaling pathway, KLF-4 (show KLF4 Antibodies) expression and miR-7 (show LILRB1 Antibodies) inhibition.

  6. overexpression of FGFBP1 (show FGFBP1 Antibodies) or loss of WISP-2 expression is closely related to the metastasis, invasion and poor prognosis of gallbladder cancer.

  7. Loss of WISP2 in estrogen-dependent MCF7 human breast cancer cells promotes a stem-like cell phenotype.

  8. We demonstrate that the overexpression of CCN5 in lung fibroblasts suppresses the upregulation in the expression of alpha-SMA (show SMN1 Antibodies) and collagen induced by CCN2 (show CTGF Antibodies).

  9. WISP2 exerts dual actions in mesenchymal precursor cells; secreted WISP2 activates canonical WNT (show WNT2 Antibodies) and maintains the cells in an undifferentiated state, whereas cytosolic WISP2 regulates adipogenic commitment.

  10. Regulation of invasion by WISP2 may involve the WNT (show WNT2 Antibodies) signalling pathway.

Mouse (Murine) WNT1 Inducible Signaling Pathway Protein 2 (WISP2) interaction partners

  1. Data suggest that CCN5, minimally expressed in unstimulated islet beta-cells, is strongly and directly induced by Igf1 (insulin-like growth factor I (show IGF1 Antibodies)); overexpression of CCN5 stimulates cell proliferation and inhibits streptozotocin-induced apoptosis.

  2. These results suggested that secreted Wisp2/CCN5 induces Akt (show AKT1 Antibodies) and ERK (show EPHB2 Antibodies) phosphorylation via integrins, and consequently facilitates neurite formation and conferred resistance to apoptosis.

  3. CCN2 (show CTGF Antibodies) is pro-hypertrophic and -fibrotic, whereas CCN5 is anti-hypertrophic and -fibrotic.

  4. Although WISP-2 is a downstream protein of Wnt (show WNT2 Antibodies) signaling, the role of WISP-2 on adipocyte differentiation may be marginal, at least in this in vitro culture model.

WISP2 Antigen Profile

Protein Summary

This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.

Gene names and symbols associated with WISP2

  • WNT1 inducible signaling pathway protein 2 (WISP2) antibody
  • WNT1 inducible signaling pathway protein 2 (wisp2) antibody
  • WNT1 inducible signaling pathway protein 2 (Wisp2) antibody
  • Ccn5 antibody
  • Crgr4 antibody
  • CT58 antibody
  • CTGF-L antibody
  • Ctgfl antibody
  • MGC84196 antibody
  • Rcop1 antibody
  • WISP2 antibody

Protein level used designations for WISP2

WNT1 inducible signaling pathway protein 2 , Wnt-1 inducible-signaling pathway protein 2 , WNT1 inducible signaling pathway 2 , zWISP2-c23 , CCN family member 5 , WISP-2 , WNT1-inducible-signaling pathway protein 2 , connective tissue growth factor-like protein , connective tissue growth factor-related protein 58 , wnt-1 signaling pathway protein 2 , CTGF-L , CCN family protein COP-1

GENE ID SPECIES
419192 Gallus gallus
444655 Xenopus laevis
458271 Pan troglodytes
610928 Canis lupus familiaris
100007759 Danio rerio
8839 Homo sapiens
22403 Mus musculus
29576 Rattus norvegicus
534658 Bos taurus
Selected quality suppliers for anti-WISP2 (WISP2) Antibodies
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