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anti-WW and C2 Domain Containing 1 (WWC1) Antibodies

The protein encoded by WWC1 is a cytoplasmic phosphoprotein that interacts with PRKC-zeta and dynein light chain-1. Additionally we are shipping WW and C2 Domain Containing 1 Kits (7) and WW and C2 Domain Containing 1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
WWC1 23286 Q8IX03
WWC1 211652 Q5SXA9
WWC1    
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Top anti-WW and C2 Domain Containing 1 Antibodies at antibodies-online.com

Showing 10 out of 46 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WWC1 Antibody (N-term) (ABIN654697) western blot analysis in ZR-75-1 cell line lysates (35 µg/lane). This demonstrates the WWC1 antibody detected the WWC1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB WWC1 Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35 µg/lane). This demonstrates the WWC1 antibody detected the WWC1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-KIBRA Polyclonal Antibody, Unconjugated (ABIN1387477) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat kidney labeled with Anti-KIBRA Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

WWC1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-WW and C2 Domain Containing 1 Antibodies

  1. Human Polyclonal WWC1 Primary Antibody for EIA, WB - ABIN955588 : Yasuda, Hashimoto, Ohi, Fukumoto, Takamura, Iike, Yoshida, Hayashi, Takahashi, Yamamori, Morihara, Tagami, Okochi, Tanaka, Kudo, Kamino, Ishii, Iwase, Kazui, Takeda: Association study of KIBRA gene with memory performance in a Japanese population. in The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 2010 (PubMed)
    Show all 5 references for ABIN955588

  2. Human Polyclonal WWC1 Primary Antibody for WB - ABIN654697 : Rose, Behm, Drgon, Johnson, Uhl: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. in Molecular medicine (Cambridge, Mass.) 2010 (PubMed)
    Show all 2 references for ABIN654697

More Antibodies against WW and C2 Domain Containing 1 Interaction Partners

Fruit Fly (Drosophila melanogaster) WW and C2 Domain Containing 1 (WWC1) interaction partners

  1. Kibra, a binding partner of Pez (show PTPN14 Antibodies), stabilizes Pez (show PTPN14 Antibodies) via WW-PY/PPxY interaction.

  2. Kibra regulates starvation-induced autophagy downstream of aPKC.

  3. In the human brain, KIBRA is mainly expressed in hippocampus and interacts with proteins involved in long-term potentiation and synaptic plasticity and effect memory in aged.

  4. The result reveals role for Kibra in neuronal specification and maintenance and show that the Hippo pathway is reimplemented for sensory neuron fate by combining canonical and noncanonical regulatory steps.

  5. Kibra functions as a tumor suppressor protein (show TP53 Antibodies) that regulates Hippo signaling in conjunction with Merlin (show NF2 Antibodies) and Expanded.

  6. Kibra is a regulator of the Salvador/Warts/Hippo signaling network.

  7. Kibra predominantly acts in the Merlin (show NF2 Antibodies) branch upstream of the core kinase cascade to regulate Hippo signaling.

Human WW and C2 Domain Containing 1 (WWC1) interaction partners

  1. Study observed a trend for a better memory performance and significantly higher volumes and better microstructural integrity in the subfields comprising the CA2 (show CA2 Antibodies)/3 and CA4 (show CA4 Antibodies)/DG of the hippocampus in KIBRA T-allele carriers compared with non-T-carriers

  2. decreased expression of the KIBRA gene on both mRNA and protein levels in depression, is reported.

  3. Phosphorylation-dependent regulation of the DNA damage response of Kibra protein in cancer cells

  4. Study did not find support for an association of KIBRA either alone or in combination with CLSTN2 (show CLSTN2 Antibodies) with memory performance or hippocampal volume, nor did variation in these genes influence longitudinal memory decline or hippocampal atrophy in older adults

  5. KIBRA rs17070145 affects specific phenotypes (high alcohol consumption, APOE (show APOE Antibodies) synergism) of Japanese patients with Alzheimer disease in an age-dependent manner. Right inferior frontal gyrus hyperperfusion was seen in the C allele carrier group.

  6. the study demonstrates an association between the KIBRA gene and episodic memory (immediate free recall) and suggests a differential effect of this genetic variant in early-onset schizophrenia and healthy siblings

  7. In brief, we showed that individuals with MD[major depression] that were WWC1 rs17070145TT carriers reported more severe 'concentration difficulties' than C-carriers.

  8. The results of this study supports the view that effects of KIBRA and CLSTN2 (show CLSTN2 Antibodies) polymorphisms genetic polymorphisms on cognitive functioning may be most easily disclosed at suboptimal levels of cognitive ability, such as in old-age depression.

  9. KIBRA is involved in human tumorigenesis and other physiological processes including cell polarity, membrane/vesicular trafficking, mitosis and cell migration.

  10. KIBRA/WWC1 rs17070145 polymorphism has effect on spatial memory in humans and age differences in the reliance on landmark and boundary-related spatial information.

Mouse (Murine) WW and C2 Domain Containing 1 (WWC1) interaction partners

  1. KIBRA levels in the rodent hippocampus correlate closely both to spatial memory performance in rodents and to PKMzeta

  2. These results indicate that KIBRA regulates higher brain function by regulating AMPAR trafficking and synaptic plasticity.

  3. KIBRA associates with and activates Lats (large tumor suppressor (show LATS1 Antibodies)) 1 and 2 kinases by stimulating their phosphorylation on the hydrophobic motif

  4. KIBRA functions in memory performance via interaction with PKMzeta.

WW and C2 Domain Containing 1 (WWC1) Antigen Profile

Protein Summary

The protein encoded by this gene is a cytoplasmic phosphoprotein that interacts with PRKC-zeta and dynein light chain-1. Alleles of this gene have been found that enhance memory in some individuals. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with WWC1

  • kibra ortholog (kibra) antibody
  • WW and C2 domain containing 1 (WWC1) antibody
  • WW, C2 and coiled-coil domain containing 1 (Wwc1) antibody
  • AA408228 antibody
  • AU017197 antibody
  • BC037006 antibody
  • CG7552 antibody
  • CG12600 antibody
  • CG33967 antibody
  • Dmel\\CG33967 antibody
  • HBEBP3 antibody
  • HBEBP36 antibody
  • kib antibody
  • KIBRA antibody
  • l(3)02404 antibody
  • l(3)j5C3 antibody
  • l(3)neo42 antibody
  • mKIAA0869 antibody
  • ORE-2 antibody
  • RE26350 antibody

Protein level used designations for WWC1

CG33967-PA , kibra-PA , lethal (3) neo42 , HBeAg-binding protein 3 , WW, C2 and coiled-coil domain containing 1 , kidney and brain protein , protein KIBRA , protein WWC1 , WW domain-containing protein 1

GENE ID SPECIES
41783 Drosophila melanogaster
23286 Homo sapiens
211652 Mus musculus
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