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Williams Beuren Syndrome Chromosome Region 22 Proteins (WBSCR22)

WBSCR22 encodes a protein containing a nuclear localization signal and an S-adenosyl-L-methionine binding motif typical of methyltransferases, suggesting that the encoded protein may act on DNA methylation. Additionally we are shipping WBSCR22 Antibodies (41) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
WBSCR22 114049 O43709
Mouse WBSCR22 WBSCR22 66138 Q9CY21
Rat WBSCR22 WBSCR22 368084  
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Top WBSCR22 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,737.17
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details

WBSCR22 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,

More Proteins for Williams Beuren Syndrome Chromosome Region 22 (WBSCR22) Interaction Partners

Human Williams Beuren Syndrome Chromosome Region 22 (WBSCR22) interaction partners

  1. The localization of the TRMT112 (show TRMT112 Proteins) protein is determined by WBSCR22, and the WBSCR22-TRMT112 (show TRMT112 Proteins) complex is localized in the cell nucleus.

  2. DIMT1L (show DIMT1 Proteins) and WBSCR22-TRMT112 (show TRMT112 Proteins) are required for distinct pre-rRNA processing reactions leading to synthesis of 18S rRNA. Ribosome biogenesis requires the presence of the modification enzyme rather than its RNA-modifying catalytic activity.

  3. Knockdown of Merm1/Wbscr22 attenuates sensitivity of H460 non-small cell lung cancer cells to SN-38 and 5-FU without alteration to p53 (show TP53 Proteins) expression levels.

  4. The key role of WBSCR22 in 40S subunit (show RPS21 Proteins) biogenesis is independent of its function as an RNA methyltransferase.

  5. WBSCR22 protein level is decreased in lymphoblastoid cell lines.

  6. Merm1 is a novel regulator of chromatin structure affecting GR recruitment and function

  7. Characterization of two novel genes, WBSCR20 (show NSUN5 Proteins) and WBSCR22, deleted in Williams-Beuren syndrome

WBSCR22 Protein Profile

Protein Summary

This gene encodes a protein containing a nuclear localization signal and an S-adenosyl-L-methionine binding motif typical of methyltransferases, suggesting that the encoded protein may act on DNA methylation. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternatively spliced transcript variants have been found.

Gene names and symbols associated with WBSCR22

  • Williams Beuren syndrome chromosome region 22 (WBSCR22)
  • Williams Beuren syndrome chromosome region 22 (wbscr22)
  • williams Beuren syndrome chromosome region 22 (CpipJ_CPIJ001394)
  • williams Beuren syndrome chromosome region 22 (PAAG_00857)
  • williams Beuren syndrome chromosome region 22 (MCYG_07273)
  • williams Beuren syndrome chromosome region 22 (PGTG_07527)
  • williams Beuren syndrome chromosome region 22 (PGTG_12505)
  • Williams Beuren syndrome chromosome region 22 (LOC100226152)
  • Williams Beuren syndrome chromosome region 22 protein (LOC100341475)
  • Williams Beuren syndrome chromosome region 22 (Wbscr22)
  • 1110003N24Rik protein
  • HASJ4442 protein
  • HUSSY-3 protein
  • MERM1 protein
  • MGC82375 protein
  • PP3381 protein
  • WBMT protein
  • zgc:162306 protein

Protein level used designations for WBSCR22

Williams Beuren syndrome chromosome region 22 protein , Williams Beuren syndrome chromosome region 22 , hypothetical protein LOC496966 , williams Beuren syndrome chromosome region 22 , Williams-Beuren candidate region putative methyltransferase , Williams-Beuren syndrome chromosomal region 22 protein , metastasis-related methyltransferase 1 , uncharacterized methyltransferase WBSCR22 , Williams-Beuren syndrome chromosomal region 22 protein homolog

GENE ID SPECIES
431053 Gallus gallus
443795 Xenopus laevis
496966 Xenopus (Silurana) tropicalis
572367 Danio rerio
6032746 Culex quinquefasciatus
9100585 Paracoccidioides sp. 'lutzii' Pb01
9226796 Arthroderma otae CBS 113480
10534661 Puccinia graminis f. sp. tritici CRL 75-36-700-3
10535199 Puccinia graminis f. sp. tritici CRL 75-36-700-3
100226152 Taeniopygia guttata
100341475 Oryctolagus cuniculus
114049 Homo sapiens
66138 Mus musculus
513878 Bos taurus
368084 Rattus norvegicus
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