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anti-Wilms Tumor 1 Interacting Protein (WTIP) Antibodies

Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Additionally we are shipping WTIP Kits (3) and WTIP Proteins (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Anti-Rat WTIP WTIP 361552  
WTIP 126374 A6NIX2
Anti-Mouse WTIP WTIP 101543 Q7TQJ8
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Top anti-WTIP Antibodies at antibodies-online.com

Showing 10 out of 23 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, IHC (p), WB WTIP Antibody (C-term) (ABIN655782) western blot analysis in NCI-H460,WiDr cell line lysates (35 µg/lane). This demonstrates the WTIP antibody detected the WTIP protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Confocal immunofluorescent analysis of WTIP Antibody (C-term) with WiDr cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). WTIP Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of WTIP Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Biotin ICC, IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated IF, IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated IF, WB Western Blot analysis of WTIP expression in transfected 293T cell line by WTIP MaxPab polyclonal antibody.Lane 1: WTIP transfected lysate(47.30 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to WTIP on HeLa cell. [antibody concentration 30 ug/ml] 100 μg Log in to see 9 Days
$418.57
Details
Human Mouse Un-conjugated IF, WB Western Blot analysis of WTIP expression in transfected 293T cell line by WTIP MaxPab polyclonal antibody.Lane 1: WTIP transfected lysate(47.3 KDa).Lane 2: Non-transfected lysate. WTIP MaxPab polyclonal antibody. Western Blot analysis of WTIP expression in human placenta. 50 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details
Human Rabbit FITC IF, IHC, ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit HRP IHC, ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details

WTIP Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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More Antibodies against WTIP Interaction Partners

Human Wilms Tumor 1 Interacting Protein (WTIP) interaction partners

  1. WTIP (show ASXL2 Antibodies)interacts with ASXL2 and blocks ASXL2-mediated activation of retin (show ASXL2 Antibodies)oic acid signaling.

  2. Wtip regulates the stable formation of cell adhesions to both extracellular matrix and neighboring cells and suggest that Wtip is necessary for normal glomerular filtration barrier function

  3. Report role of WTIP in regulating podocyte phenotype in chronic kidney disease.

  4. Full-length Ror2 (show ROR2 Antibodies) recruits Wtip to the cell membrane, a mutant involved in human disease fails to do so. Both genes and proteins show overlapping expression in the mouse embryo.

  5. WTIP is a member of the Ajuba (show AJUBA Antibodies) family of LIM (show PDLIM5 Antibodies)-domain containing proteins. Ajuba (show AJUBA Antibodies) LIM (show PDLIM5 Antibodies) proteins co-repress E-cadherin (show CDH1 Antibodies) expression through interaction with the SNAG domain of Snail (show SNAI1 Antibodies)/Slug (show SNAI2 Antibodies) and promote epithelial to mesenchymal differentiation in a Xenopus model.

  6. Stress signaling pathways initiate WTIP nuclear translocation, and the concomitant loss of WTIP from cell contacts changes podocyte morphology and dynamic actin assembly, suggesting a mechanism that transmits changes in podocyte morphology to the nucleus.

  7. WTIP monitors slit diaphragm protein assembly as part of a multiple protein complex, linking this specialized adhesion junction to the actin cytoskeleton, and shuttles into the nucleus after podocyte injury

Mouse (Murine) Wilms Tumor 1 Interacting Protein (WTIP) interaction partners

  1. implicate Asxl1 (show ASXL1 Antibodies) in the maintenance of podocyte structure via its association with Wtip and in the regulation of WT1 (show WT1 Antibodies) signaling during early kidney development

  2. ASXL2 (show ASXL2 Antibodies) and WTIP are expressed in mouse embryonic epicardial cells. ASXL2 (show ASXL2 Antibodies) and WTIP participate in regulation of retinoic acid signaling during heart development.

  3. Dendrin is dispensable for the function of the normal glomerular filtration barrier, and it interacts with Wtip and Gadd45a (show GADD45A Antibodies).

  4. Wtip regulates the stable formation of cell adhesions to both extracellular matrix and neighboring cells and suggest that Wtip is necessary for normal glomerular filtration barrier function

  5. Podocyte injury induces nuclear translocation of WTIP via microtubule-dependent transport

  6. WTIP monitors slit diaphragm protein assembly as part of a multiple protein complex, linking this specialized adhesion junction to the actin cytoskeleton, and shuttles into the nucleus after podocyte injury

  7. Full-length Ror2 (show ROR2 Antibodies) recruits Wtip to the cell membrane, a mutant involved in human disease fails to do so.

WTIP Antigen Profile

Protein Summary

Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA)-mediated gene silencing. Negatively regulates Hippo signaling pathway and antagonizes phosphorylation of YAP1. Acts as a transcriptional corepressor for SNAI1 and SNAI2/SLUG-dependent repression of E-cadherin transcription. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A. May monitor slit diaphragm protein assembly, a specialized adherens junction characteristic of podocytes. In case of podocyte injury, it shuttles into the nucleus and acts as a transcription regulator that represses WT1- dependent transcription regulation, thereby translating changes in slit diaphragm structure into altered gene expression and a less differentiated phenotype.

Gene names and symbols associated with WTIP

  • Wilms tumor 1 interacting protein (Wtip) antibody
  • Wilms tumor 1 interacting protein (WTIP) antibody
  • Wilms tumor 1 interacting protein (wtip) antibody
  • WT1-interacting protein (Wtip) antibody
  • RGD1306411 antibody
  • si:ch211-79l17.3 antibody

Protein level used designations for WTIP

WT1-interacting protein , Wilms tumor protein 1-interacting protein , Wilms tumor protein 1-interacting protein homolog , WT1-interacting protein homolog , Wilms tumor 1 interacting protein , xWtip

GENE ID SPECIES
361552 Rattus norvegicus
505059 Bos taurus
566046 Danio rerio
747259 Pan troglodytes
769595 Gallus gallus
126374 Homo sapiens
100127345 Xenopus laevis
101543 Mus musculus
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