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Wilms Tumor 1 Interacting Protein (WTIP) ELISA Kits

Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Additionally we are shipping WTIP Antibodies (23) and WTIP Proteins (2) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat WTIP WTIP 361552  
WTIP 126374 A6NIX2
WTIP 101543 Q7TQJ8
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Top WTIP ELISA Kits at antibodies-online.com

Showing 2 out of 3 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 0.39-25 ng/mL 96 Tests Log in to see 11 to 13 Days
$875.60
Details
Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
Details

More ELISA Kits for WTIP Interaction Partners

Human Wilms Tumor 1 Interacting Protein (WTIP) interaction partners

  1. WTIP (show ASXL2 ELISA Kits)interacts with ASXL2 and blocks ASXL2-mediated activation of retin (show ASXL2 ELISA Kits)oic acid signaling.

  2. Wtip regulates the stable formation of cell adhesions to both extracellular matrix and neighboring cells and suggest that Wtip is necessary for normal glomerular filtration barrier function

  3. Report role of WTIP in regulating podocyte phenotype in chronic kidney disease.

  4. Full-length Ror2 (show ROR2 ELISA Kits) recruits Wtip to the cell membrane, a mutant involved in human disease fails to do so. Both genes and proteins show overlapping expression in the mouse embryo.

  5. WTIP is a member of the Ajuba (show AJUBA ELISA Kits) family of LIM (show PDLIM5 ELISA Kits)-domain containing proteins. Ajuba (show AJUBA ELISA Kits) LIM (show PDLIM5 ELISA Kits) proteins co-repress E-cadherin (show CDH1 ELISA Kits) expression through interaction with the SNAG domain of Snail (show SNAI1 ELISA Kits)/Slug (show SNAI2 ELISA Kits) and promote epithelial to mesenchymal differentiation in a Xenopus model.

  6. Stress signaling pathways initiate WTIP nuclear translocation, and the concomitant loss of WTIP from cell contacts changes podocyte morphology and dynamic actin assembly, suggesting a mechanism that transmits changes in podocyte morphology to the nucleus.

  7. WTIP monitors slit diaphragm protein assembly as part of a multiple protein complex, linking this specialized adhesion junction to the actin cytoskeleton, and shuttles into the nucleus after podocyte injury

Mouse (Murine) Wilms Tumor 1 Interacting Protein (WTIP) interaction partners

  1. implicate Asxl1 (show ASXL1 ELISA Kits) in the maintenance of podocyte structure via its association with Wtip and in the regulation of WT1 (show WT1 ELISA Kits) signaling during early kidney development

  2. ASXL2 (show ASXL2 ELISA Kits) and WTIP are expressed in mouse embryonic epicardial cells. ASXL2 (show ASXL2 ELISA Kits) and WTIP participate in regulation of retinoic acid signaling during heart development.

  3. Dendrin is dispensable for the function of the normal glomerular filtration barrier, and it interacts with Wtip and Gadd45a (show GADD45A ELISA Kits).

  4. Wtip regulates the stable formation of cell adhesions to both extracellular matrix and neighboring cells and suggest that Wtip is necessary for normal glomerular filtration barrier function

  5. Podocyte injury induces nuclear translocation of WTIP via microtubule-dependent transport

  6. WTIP monitors slit diaphragm protein assembly as part of a multiple protein complex, linking this specialized adhesion junction to the actin cytoskeleton, and shuttles into the nucleus after podocyte injury

  7. Full-length Ror2 (show ROR2 ELISA Kits) recruits Wtip to the cell membrane, a mutant involved in human disease fails to do so.

WTIP Antigen Profile

Antigen Summary

Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA)-mediated gene silencing. Negatively regulates Hippo signaling pathway and antagonizes phosphorylation of YAP1. Acts as a transcriptional corepressor for SNAI1 and SNAI2/SLUG-dependent repression of E-cadherin transcription. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A. May monitor slit diaphragm protein assembly, a specialized adherens junction characteristic of podocytes. In case of podocyte injury, it shuttles into the nucleus and acts as a transcription regulator that represses WT1- dependent transcription regulation, thereby translating changes in slit diaphragm structure into altered gene expression and a less differentiated phenotype.

Gene names and symbols associated with WTIP

  • Wilms tumor 1 interacting protein (Wtip) antibody
  • Wilms tumor 1 interacting protein (WTIP) antibody
  • Wilms tumor 1 interacting protein (wtip) antibody
  • WT1-interacting protein (Wtip) antibody
  • RGD1306411 antibody
  • si:ch211-79l17.3 antibody

Protein level used designations for WTIP

WT1-interacting protein , Wilms tumor protein 1-interacting protein , Wilms tumor protein 1-interacting protein homolog , WT1-interacting protein homolog , Wilms tumor 1 interacting protein , xWtip

GENE ID SPECIES
361552 Rattus norvegicus
505059 Bos taurus
566046 Danio rerio
747259 Pan troglodytes
769595 Gallus gallus
126374 Homo sapiens
100127345 Xenopus laevis
101543 Mus musculus
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