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The WNT gene family consists of structurally related genes which encode secreted signaling proteins. Additionally we are shipping WNT11 Antibodies (25) and WNT11 Kits (9) and many more products for this protein.
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Because paraxial protocadherin and C-cadherin do not directly interact nor form a joint complex with Fz7, Wnt-11 triggers formation of two distinct complexes that act in parallel to reduce cell adhesion by hampering clustering of C-cadherin.
PAR-1 (show F2R Proteins) RNA rescues neural cell markers in embryos in which noncanonical Wnt (show WNT2 Proteins) signaling has been blocked. Novel roles for Wnt11R and PAR-1 (show F2R Proteins) were identified in neural cell specification. An unexpected connection was shown between morphogenesis and cell fate.
Xenopus Wnt11-R is expressed in neural tissue, the brachial arches, and the muscle layer of the heart.
Wnt11-R signaling regulates a calcium sensitive EMT (show ITK Proteins) event essential for dorsal fin development of Xenopus.
wnt11r is required in a non-cell-autonomous manner to control neural crest migration.
under tensile stress, miR (show MLXIP Proteins)-154-5p negatively regulates ADSCs osteogenic differentiation through the Wnt (show WNT2 Proteins)/PCP (show BMP1 Proteins) pathway by directly targeting Wnt11
a mechanistic link between E-cadherin (show CDH1 Proteins) loss and subsequent control of Rho-driven anoikis resistance through p120 (show CTNND1 Proteins)- and Kaiso (show ZBTB33 Proteins)-dependent expression of Wnt11, is reported.
Studied groups of embryoid bodies (EBs) with different starting numbers of ESCs (show NR2E3 Proteins) & found differential gene expression patterns for Wnt5a (show WNT5A Proteins) & Wnt11. Wnt11 inc'd the percentage of beating EBs by upregulating expression of cardiac-specific genes.
Data show that Wnt5a (show WNT5A Proteins) and Wnt11 are required for proper patterning of the neural tube and somites by regulating notochord formation.
These results provide formal genetic proof that the majority of the endocardium and myocardium diverge by mid-gastrulation in the mouse, and suggest a tight spatial and temporal control of Wnt11 expression in the myocardial lineage.
Wnt5a (show WNT5A Proteins)/Wnt11 inhibit beta-catenin (show CTNNB1 Proteins) to promote SHF (show SHF Proteins) development through Caspase (show CASP3 Proteins)-dependent Akt (show AKT1 Proteins) degradation
Notch1 (show NOTCH1 Proteins)-induced WISP-1 (show WISP1 Proteins) expression appeared to be Wnt11-dependent, but Wnt1 (show WNT1 Proteins)-independent
The apical and basolateral secretion of Wnt11 and Wnt3a (show WNT3A Proteins) in polarized epithelial cells is regulated by different mechanisms.
demonstrates that the combination of Wnt11 and BMP-2 (show BMP2 Proteins) effectively promotes cardiomyogenic differentiation of BM-MSCs in vitro. The synergistic effect of Wnt11 and BMP-2 (show BMP2 Proteins) on the cardiomyogenic differentiation of BM-MSCs is further enhanced in myocardium
all the TGF-beta (show TGFB1 Proteins), Wnt11, and JNK (show MAPK8 Proteins) targets were activated in a unilateral ureteral obstruction (UUO) model of renal fibrosis in vivo.
Data suggest that Wnt-11 may serve as a target for cervical cancer therapy.
The Wnt11 gene plays an important role in human mesenchymal stromal cells for enhancing the osteogenesis in an infectious environment.
Demonstrate immunohistochemical expression of Wnt11 and BCL2A1 (show BCL2A1 Proteins) in complete moles and normal villi.
Report high expression of Wnt11 in esophageal squamous cell carcinoma, which was significantly associated with AJCC stage.
High expression of Wnt-11 is associated with metastasis in cervical cancer.
differential Wnt11 immunoexpression in high-grade human serous ovarian cancer compared to low-grade human serous ovarian cancer could play important roles in serous ovarian cancer progression and may be modulated by Wnt5a (show WNT5A Proteins) expression levels.
Data established a seven-gene (AR, ESR2 (show ESR2 Proteins), GATA3 (show GATA3 Proteins), GBX2 (show GBX2 Proteins), KRT16 (show KRT16 Proteins), MMP28 (show MMP28 Proteins) and WNT11) prognostic signature to define a subset of triple-negative breast cancer (TNBC).
Estrogen/progesterone treatment of mature myometrial cells induced expression of WNT11 and WNT16 (show WNT16 Proteins), which remained constitutively elevated in leiomyoma tissues.
Wnt11 mRNA expression was significantly higher in the stage I, II, III, or IV colorectal tumor tissues than in non-tumor colon.
data suggest an important role of Ror2 (show ROR2 Proteins) in mediating Wnt11 signaling and in regulating convergence and extension movements in zebrafish.
Swap70b and Def6a (show DEF6 Proteins) delineate Wnt11 and Wnt5b (show WNT5B Proteins) signalling pathways and have roles in convergent and extension cell movement during zebrafish gastrulation
CTCF (show CTCF Proteins) acts upstream of wnt11 during zebrafish muscle development.
findings provide the first evidence that wnt11 itself is a downstream target of the Jnk (show MAPK8 Proteins) cascade in the non-canonical Wnt (show WNT2 Proteins) pathway
data reveal a previously unrecognized role for Wnt (show WNT2 Proteins)/Ca(2 (show CA2 Proteins)+) signalling in establishing an electrical gradient in the plane of the developing cardiac epithelium through modulation of ion-channel function
Wnt11 and Prickle1a are expressed in the dorsal forerunner cells and regulate Kupffer's vesicle morphogenesis.
three Wnt (show WNT2 Proteins) noncanonical ligands wnt4a, silberblick/wnt11, and wnt11-related regulate the process of convergence of endoderm and organ precursors toward the embryonic midline by acting in a largely redundant way
wnt11 and Fz5 signaling promotes early eye development through the coordinated antagonism of signals that suppress retinal identity
Results suggest that Wnt11 controls tissue morphogenesis by modulating E-cadherin (show CDH1 Proteins)-mediated cell cohesion through Rab5c (show Rab5c Proteins), a novel mechanism of Wnt (show WNT2 Proteins) signaling in gastrulation.
with combined loss of Tbx16 and Wnt11 (Silberblick), coalesence is essentially absent. Possibly as a consequence, both the anterior movement of presumptive prechordal plate and organizer function, as assayed by eye-field separation, are disrupted.
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 97%, 85%, and 63% amino acid identity with mouse, chicken, and Xenopus Wnt11 protein, respectively. This gene may play roles in the development of skeleton, kidney and lung, and is considered to be a plausible candidate gene for High Bone Mass Syndrome.
, WNT11-related protein
, protein Wnt-11-related
, wingless-type MMTV integration site family, member 11
, protein Wnt-11b-2
, protein Wnt-11-like
, Wnt-11 protein
, wingless-related MMTV integration site 11