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The WNT gene family consists of structurally related genes which encode secreted signaling proteins. Additionally we are shipping WNT5B Antibodies (62) and WNT5B Kits (11) and many more products for this protein.
Showing 6 out of 6 products:
Wnt5b activated known calcium-dependent signaling pathways and JNK (show MAPK8 Proteins), a component of the planar cell polarity pathway.
Secreted Wnt (show WNT2 Proteins) glycoproteins, expressed by thymic epithelial cells and thymocytes, regulate epithelial Foxn1 (show FOXN2 Proteins) expression in both autocrine and paracrine fashions. Wnt (show WNT2 Proteins) molecules therefore provide regulatory signals critical for thymic function.
Data indicate that Wnt5a (show WNT5A Proteins) and Wnt5b control the pace of transitions between different chondrocyte zones.
Wnt5b may promote adipogenesis in 3T3-L1 cells, at least in part, by antagonizing the canonical Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) pathway
hCG (show CGA Proteins) was found to up-regulate these wnt (show WNT2 Proteins) ligands in mouse mammary gland, independent of the changes in ovarian steroidogenesis
this study aimed at defining the expression profile and function of Wnt5a (show WNT5A Proteins) and Wnt5b during adipogenesis by determining their effect on aP2 (show TFAP2A Proteins) and PPARgamma (show PPARG Proteins) expression and assessing the level of beta-catenin (show CTNNB1 Proteins) translocation in mouse 3T3-L1 preadipocytes.
Together these findings provide important and novel insights into the role of canonical Wnt (show WNT2 Proteins) signals during the patterning of vertebrate ectoderm and indicate that Wnt (show WNT2 Proteins) inhibition plays a central role in the process of neural induction.
The interaction between Wnt (show WNT2 Proteins) isoforms and their LRP6 (show LRP6 Proteins) cognate receptor depends on the jutting loop present in Wnt3a (show WNT3A Proteins) but absent in Wnt5b.
Results demonstrate that the Wnt5B pathway may play an important role in atypical teratoid rhabdoid tumor biology.
Report increased Wnt5b levels in adriamycin treated liver cancer stem cells within 4h of treatment.
This study shows that the WNT5B germline variant rs2010851 was significantly identified as a stage-dependent prognostic marker for CC patients after 5-fluorouracil-based adjuvant therapy.
WNT5B is elevated in both in the tumor and the patients' serum from triple negative breast cancer.
Knocking down Wnt5b expression reduced phospho-PKCA (show PKCa Proteins) levels and cell migration.
Ursolic acid suppressed the expression of Wnt5alpha/beta and beta-catenin (show CTNNB1 Proteins), inducing apoptosis in prostate cancer cells.
These results indicate that Wnt5b is involved in the migration ability of OSCC cells through active Cdc42 (show CDC42 Proteins) and RhoA (show RHOA Proteins).
WNT3 (show WNT3 Proteins) and WNT5B are critical factors, secreted from mesenchymal cancer cells, for instigating the epithelial cancer cell invasion.
TGF-beta (show TGFB1 Proteins)/Smad (show SMAD1 Proteins), integrin/integrin-linked kinase (ILK (show ILK Proteins)) and wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling pathways are involved in epithelial to mesenchymal transition in human renal fibrogenesis.
novel mechanism for Wnt5b and Gpc4 (show GPC4 Proteins) regulation of chondrocyte behavior that is independent of the core Wnt (show WNT2 Proteins)/PCP (show PRCP Proteins) molecules and differs from their collaborative action of controlling cell movements during gastrulation
In embryos overexpressing lbx1b (show Lbx1 Proteins), wnt5b, a ligand of the non-canonical Wnt (show WNT2 Proteins)/planar cell polarity (PCP (show PRCP Proteins)) pathway, was significantly downregulated.
Swap70b and Def6a (show DEF6 Proteins) delineate Wnt11 (show WNT11 Proteins) and Wnt5b signalling pathways and have roles in convergent and extension cell movement during zebrafish gastrulation
CNBP (show CNBP Proteins) up-regulates tbx2b and smarca5 (show SMARCA5 Proteins), and down-regulates wnt5b gene expression.
def6 (show DEF6 Proteins) morphants phenocopy Wnt5b mutants and ectopic overexpression of def6 (show DEF6 Proteins) essentially rescues Wnt5b morphants, indicating a novel role for def6 (show DEF6 Proteins) as a central GEF (show SLC2A4RG Proteins) downstream of Wnt5b signaling
identify rgs3 (show RGS3 Proteins) as having an overlapping expression pattern with wnt5b in zebrafish and reveal that individual knockdown of either rgs3 (show RGS3 Proteins) or wnt5b gene function produces similar somite patterning defects.
Data suggest that full-length Ryk (show RYK Proteins) conveys Wnt5b signals in a directional manner during gastrulation.
Data suggest that the Wnt-5 loss-of-function defect is consistent with calcium modulation having an antagonistic interaction with Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling.
conserved role of a Wnt5 (show WNT5A Proteins)/Fz2 (show FZD2 Proteins) signaling pathway in islet formation during pancreatic development.
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 94% and 80% amino acid identity to the mouse Wnt5b protein and the human WNT5A protein, respectively. Alternative splicing of this gene generates 2 transcript variants.
wingless-type MMTV integration site family, member 5B
, protein Wnt-5b
, protein Wnt-5c
, wingless-type MMTV integration site family, member 5
, WNT-5B protein
, wingless-related MMTV integration site 5B
, pipe tail