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anti-Wolf-Hirschhorn Syndrome Candidate 1-Like 1 (WHSC1L1) Antibodies

WHSC1L1 is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. Additionally we are shipping WHSC1L1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
WHSC1L1 290831  
WHSC1L1 54904 Q9BZ95
WHSC1L1 234135 Q6P2L6
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Top anti-WHSC1L1 Antibodies at antibodies-online.com

Showing 10 out of 52 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of WHSC1L1 (arrow) using rabbit polyclonal WHSC1L1 Antibody (N-term) (ABIN656685). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the WHSC1L1 gene. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of WHSC1L1 (arrow) using rabbit polyclonal WHSC1L1 Antibody (N-term) . 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the WHSC1L1 gene. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated EIA, WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Mouse Un-conjugated ELISA, WB Western blot analysis: Cell lysates of HeLa (40ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human NSD3 (1:2,000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. 100 μL Log in to see 7 to 8 Days
$374.00
Details
Human Mouse Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$527.15
Details
Human Rabbit FITC ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit HRP ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

WHSC1L1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)


Human , ,
,
,
, , , , ,
Mouse (Murine)


Top referenced anti-WHSC1L1 Antibodies

  1. Human Polyclonal WHSC1L1 Primary Antibody for EIA, WB - ABIN955576 : Zhou, Thomsen, Kahns, Nielsen: The NSD3L histone methyltransferase regulates cell cycle and cell invasion in breast cancer cells. in Biochemical and biophysical research communications 2010 (PubMed)
    Show all 4 references for ABIN955576

  2. Human Polyclonal WHSC1L1 Primary Antibody for WB - ABIN656685 : Tonon, Wong, Maulik, Brennan, Feng, Zhang, Khatry, Protopopov, You, Aguirre, Martin, Yang, Ji, Chin, Depinho: High-resolution genomic profiles of human lung cancer. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)
    Show all 3 references for ABIN656685

  3. Human Monoclonal WHSC1L1 Primary Antibody for ELISA, WB - ABIN306431 : Angrand, Apiou, Stewart, Dutrillaux, Losson, Chambon: NSD3, a new SET domain-containing gene, maps to 8p12 and is amplified in human breast cancer cell lines. in Genomics 2001 (PubMed)
    Show all 2 references for ABIN306431

  4. Human Monoclonal WHSC1L1 Primary Antibody for EIA, WB - ABIN317544 : Stec, Nagl, van Ommen, den Dunnen: The PWWP domain: a potential protein-protein interaction domain in nuclear proteins influencing differentiation? in FEBS letters 2000 (PubMed)
    Show all 2 references for ABIN317544

More Antibodies against WHSC1L1 Interaction Partners

Human Wolf-Hirschhorn Syndrome Candidate 1-Like 1 (WHSC1L1) interaction partners

  1. Studies indicate that the NSD methyltransferases NSD1 (show NSD1 Antibodies), NSD2/WHSC1/MMSET (show WHSC1 Antibodies) and NSD3/WHSC1L1 were overexpressed, amplified or somatically mutated in multiple types of cancer, suggesting their critical role in cancer.

  2. Results demonstrate that the AML (show RUNX1 Antibodies) maintenance function of BRD4 (show BRD4 Antibodies) requires its interaction with the short isoform of NSD3 lacking the methyltransferase domain. This protein is an adaptor that sustains leukemia by linking BRD4 (show BRD4 Antibodies) to the CHD8 (show CHD8 Antibodies) chromatin remodeler.

  3. The results describe the binding of NSD1 (show NSD1 Antibodies), 2 and 3 catalytic domains (CD) on histone tails through recognition of histone-lysine and methylation properties.

  4. The involvement of the NSD3 methyltransferase as a component of the NUT fusion protein oncogenic complex identifies a new potential therapeutic target.

  5. PPAPDC1B (show PPAPDC1B Antibodies) and WHSC1L1 played a major role in regulating the survival of breast cancer, pancreatic adenocarcinoma and small-cell lung cancer-derived cell lines.

  6. Data indicate that siRNA attenuated the expression levels of CCNG1 (show CCNG1 Antibodies) and NEK7 (show NEK7 Antibodies), implying that WHSC1L1 appears to activate the expression of CCNG1 (show CCNG1 Antibodies) and NEK7 (show NEK7 Antibodies) in cancer cells.

  7. methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 (show HIST3H3 Antibodies) recognition

  8. Functional studies with Brd4 (show BRD4 Antibodies) indicate that the ET domain mediates pTEFb (show CDK9 Antibodies)-independent transcriptional activation through a subset of these associated factors, including NSD3.

  9. Overexpression of WHSC1L1 gene is associated with breast cancer.

WHSC1L1 Antigen Profile

Protein Summary

This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. The function of the protein has not been determined. Two alternatively spliced variants have been described.

Gene names and symbols associated with WHSC1L1

  • Wolf-Hirschhorn syndrome candidate 1-like 1 (Whsc1l1) antibody
  • Wolf-Hirschhorn syndrome candidate 1-like 1 (WHSC1L1) antibody
  • Wolf-Hirschhorn syndrome candidate 1-like 1 (whsc1l1) antibody
  • Wolf-Hirschhorn syndrome candidate 1-like 1 (LOC100228404) antibody
  • Wolf-Hirschhorn syndrome candidate 1-like 1 (human) (Whsc1l1) antibody
  • 6720429E03 antibody
  • A530023P05 antibody
  • AI528490 antibody
  • NSD3 antibody
  • pp14328 antibody
  • WHISTLE antibody
  • WHSC1L1 antibody

Protein level used designations for WHSC1L1

histone-lysine N-methyltransferase NSD3 , Wolf-Hirschhorn syndrome candidate 1-like 1 , histone-lysine N-methyltransferase NSD3-like , WHSC1-like 1 isoform 9 with methyltransferase activity to lysine , WHSC1-like protein 1 , nuclear SET domain-containing protein 3 , protein whistle , wolf-Hirschhorn syndrome candidate 1-like protein 1 homolog

GENE ID SPECIES
290831 Rattus norvegicus
426778 Gallus gallus
464119 Pan troglodytes
475584 Canis lupus familiaris
700254 Macaca mulatta
100006350 Danio rerio
100029834 Monodelphis domestica
100057692 Equus caballus
100074284 Ornithorhynchus anatinus
100216035 Xenopus (Silurana) tropicalis
100228404 Taeniopygia guttata
100352710 Oryctolagus cuniculus
100389349 Callithrix jacchus
100459660 Pongo abelii
100550821 Meleagris gallopavo
100558428 Anolis carolinensis
100599595 Nomascus leucogenys
54904 Homo sapiens
234135 Mus musculus
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