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anti-Xanthine Dehydrogenase (XDH) Antibodies

Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. Additionally we are shipping Xanthine Dehydrogenase Kits (32) and Xanthine Dehydrogenase Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
XDH 7498 P47989
XDH 22436 Q00519
XDH 497811 P22985
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Top anti-Xanthine Dehydrogenase Antibodies at antibodies-online.com

Showing 10 out of 85 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of XDH Antibody (N-term) (ABIN653225) in mouse lung tissue lysates (35 µg/lane). XDH (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with XDH Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with XDH Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Western blot analysis of XDH Antibody (N-term) in mouse lung tissue lysates (35 µg/lane). XDH (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Rabbit Un-conjugated EIA, IHC (p), IP, WB 0.5 mg Log in to see 6 to 8 Days
$500.50
Details
Cow Rabbit Un-conjugated EIA, IP, WB   2 mL Log in to see 6 to 8 Days
$1,435.50
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC (p), IP, ELISA, WB Human Liver (formalin-fixed, paraffin-embedded) stained with XDH antibody ABIN790307 at 2.5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 500 μg Log in to see 8 to 10 Days
$451.00
Details
Cow Rabbit Un-conjugated IHC (p), IP, WB Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details
Cow Rabbit Un-conjugated ELISA   100 μg Log in to see 2 to 3 Days
$369.00
Details
Cow Guinea Pig Un-conjugated IHC (fro), IHC (p), WB   0.1 mL Log in to see 6 to 8 Days
$445.50
Details
Cow Rabbit Un-conjugated IP, IHC, ELISA, WB 0.05 mg Log in to see 2 to 3 Days
$481.25
Details

XDH Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Xanthine Dehydrogenase Antibodies

  1. Human Polyclonal XDH Primary Antibody for FACS, IHC (p) - ABIN653225 : Ross, Katzov-Eckert, Dubé, Brooks, Rassekh, Barhdadi, Feroz-Zada, Visscher, Brown, Rieder, Rogers, Phillips, Carleton, Hayden: Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy. in Nature genetics 2009 (PubMed)
    Show all 2 references for ABIN653225

  2. Cow (Bovine) Polyclonal XDH Primary Antibody for EIA, IHC (p) - ABIN372510 : Mumbengegwi, Li, Li, Bear, Engelhardt: Evidence for a superoxide permeability pathway in endosomal membranes. in Molecular and cellular biology 2008 (PubMed)
    Show all 2 references for ABIN372510

  3. Cow (Bovine) Polyclonal XDH Primary Antibody for IHC (fro), IHC (p) - ABIN401670 : Jarasch, Grund, Bruder, Heid, Keenan, Franke: Localization of xanthine oxidase in mammary-gland epithelium and capillary endothelium. in Cell 1981 (PubMed)

  4. Cow (Bovine) Polyclonal XDH Primary Antibody for EIA, IP - ABIN116853 : Robenek, Hofnagel, Buers, Lorkowski, Schnoor, Robenek, Heid, Troyer, Severs: Butyrophilin controls milk fat globule secretion. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)

More Antibodies against Xanthine Dehydrogenase Interaction Partners

Pig (Porcine) Xanthine Dehydrogenase (XDH) interaction partners

Cow (Bovine) Xanthine Dehydrogenase (XDH) interaction partners

  1. Data suggest that XDH (xanthine dehydrogenase) can be an important redox-regulated source of superoxide generation in ischemic tissue; conversion XDH to XO (xanthine oxidase) is not required to activate radical formation and subsequent tissue injury.

  2. crystal structures of the urate complexes of the demolybdo-form of the D428A mutant of rat xanthine oxidoreductase and of the reduced bovine milk enzyme [XOR]

  3. Plasma tumor necrosis factor-alpha response to either of two lipopolysaccharide challenges was lower in progesterone-treated than in 17beta-estradiol-treated steers. Xanthine oxidase response to either challenge was greater for estradiol-treated steers.

  4. 6,8-dihydroxypurine is effectively converted to uric acid by xanthine oxidase.

  5. Hydrogen peroxide is the major oxidant product of xanthine oxidase

  6. Phe-549, Arg-335, Trp (show TRPC5 Antibodies)-336, & Arg-427 form the core of a relay system for the XDH/XO transition.They gate a solvent channel leading toward the FAD (show PSEN1 Antibodies) ring.

  7. Results describe the formation of peroxynitrite from the simultaneous reduction of nitrite and oxygen by xanthine oxidase.

  8. Stimulation of XDH conversion to xanthine oxidase may represent a feed-forward mechanism whereby H2O2 can stimulate further production of reactive oxygen species

  9. evidence xanthine oxidase (XO) is regulated by transmembrane secretion of xanthine &/or hypoxanthine to extracellular environment; response of XO to bacteria & bacteria-dependent nitrosative stress demonstrates it is part of mammary gland immune system

  10. Substrate Orientation and Catalysis at the Molybdenum Site in Xanthine Oxidase: CRYSTAL STRUCTURES IN COMPLEX WITH XANTHINE AND LUMAZINE.

Human Xanthine Dehydrogenase (XDH) interaction partners

  1. Thyroid stimulating hormone levels are increase in gout patients treated with inhibitors of xanthine oxidoreductase.

  2. The XDH gene polymorphisms rs1042039, rs1054889, and rs2073316 were shown to be associated with hypertension in a rural Chinese population.

  3. the essential role of autophagy-regulated early ROS (show ROS1 Antibodies) in triggering late apoptotic signaling

  4. XOR regulated macrophage IL-1b secretion upon NLRP3 inflammasome activation via xanthine oxidase derived reactive oxygen species.

  5. In this review, we focus on studies of XOR inhibitors and their implications for understanding the chemical nature and reaction mechanism of the Moco active site of XOR

  6. xanthine oxidase-mediated ROS (show ROS1 Antibodies) production is required for PTN (show PTN Antibodies)-induced cell migration through the cell membrane functional complex of alphanubeta3 and RPTPbeta (show PTPRZ1 Antibodies)/zeta and activation of c-src (show SRC Antibodies), PI3K (show PIK3CA Antibodies) and ERK1/2 (show MAPK1/3 Antibodies) kinases

  7. Data suggest that, with aging, up-regulation of reactive oxygen species derived from XO down-regulates uric acid excretion via down-regulation of active homodimer breast cancer resistance protein (BCRP1 (show ABCG2 Antibodies), uric acid efflux transporter) in ileal mucosa.

  8. Xanthine oxidase is activated in THP-1 (show GLI2 Antibodies) human myeloid cells in response to pro-inflammatory and growth factor stimulation.

  9. Xanthine oxidoreductase has roles in atherosclerosis pathogenesis [review]

  10. Xanthine dehydrogenase takes part in retinoic acid biosynthesis in the thyroid glandular epithelia.

Mouse (Murine) Xanthine Dehydrogenase (XDH) interaction partners

  1. inflammasome activation accompanied by an increase in xanthine oxidoreductase activity contributed to fat pad inflammation followed by osteoarthritis progression

  2. XOR is abundant in wounds and participates in normal wound healing through effects on ROS (show ROS1 Antibodies) production.

  3. XOR regulated macrophage IL-1b secretion upon NLRP3 inflammasome activation via xanthine oxidase derived reactive oxygen species.

  4. Xanthine oxidase inhibitors are potentially potent therapies for patients with NASH (show SAMSN1 Antibodies), particularly that associated with hyperuricemia.

  5. these data support a novel function of the XO-NFAT5 (show NFAT5 Antibodies) axis in macrophage activation and TLR-induced arthritis

  6. Reduction in XOR gene expression in mice augments lipid accumulation in adipocytes, accompanied by an increase in oxidative stress, and induces obesity with insulin (show INS Antibodies) resistance in older age.

  7. Rat Xdh is a moonlighting protein that has two distinct catalytic activities as a dehydrogenase and an oxidase.

  8. Mouse Xdh is a moonlighting protein that has two distinct catalytic activities and acts a structural protein in milk fat droplets.

  9. In conclusion, CS increases XOR expression, and the enzyme is both sufficient and necessary for p53 (show TP53 Antibodies) induction and CS-induced EC apoptosis.

  10. we have established a mouse model for autosomal recessive early-onset renal failure due to a nonsense mutation in Xdh that is a model for xanthinuria in man.

Xanthine Dehydrogenase (XDH) Antigen Profile

Protein Summary

Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The enzyme is a homodimer. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.

Gene names and symbols associated with XDH

  • xanthine dehydrogenase (XDH) antibody
  • xanthine dehydrogenase (xdh) antibody
  • Xanthine dehydrogenase (Deipr_2150) antibody
  • Xanthine dehydrogenase (Deipr_2594) antibody
  • Xanthine dehydrogenase (Trebr_1754) antibody
  • xanthine dehydrogenase (Xdh) antibody
  • DDBDRAFT_0219626 antibody
  • DDBDRAFT_0230176 antibody
  • DDB_0219626 antibody
  • DDB_0230176 antibody
  • im:7146167 antibody
  • XDH antibody
  • XO antibody
  • Xor antibody
  • Xox-1 antibody
  • Xox1 antibody

Protein level used designations for XDH

XDH xanthine dehydrogenase , xanthine oxidase , xanthine dehydrogenase , Xanthine dehydrogenase/oxidase , xanthine dehydrogenase/oxidase-like , Xanthine dehydrogenase , xanthine dehydrogenase/oxidase , xanthene dehydrogenase , xanthine oxidoreductase

GENE ID SPECIES
100515259 Sus scrofa
470347 Pan troglodytes
483028 Canis lupus familiaris
560486 Danio rerio
576712 Strongylocentrotus purpuratus
780499 Ovis aries
8627921 Dictyostelium discoideum AX4
100031481 Monodelphis domestica
100380763 Salmo salar
100414932 Callithrix jacchus
100465942 Ailuropoda melanoleuca
10265470 Deinococcus proteolyticus MRP
10265681 Deinococcus proteolyticus MRP
10580277 Treponema brennaborense DSM 12168
280960 Bos taurus
7498 Homo sapiens
22436 Mus musculus
497811 Rattus norvegicus
493692 Felis catus
396025 Gallus gallus
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