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XiAP Associated Factor 1 (XAF1) ELISA Kits

XAF1 encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. Additionally we are shipping XAF1 Antibodies (92) and XAF1 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human XAF1 XAF1 54739 Q6GPH4
Anti-Mouse XAF1 XAF1 327959 Q5NBU8
Anti-Rat XAF1 XAF1 679600  
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More ELISA Kits for XAF1 Interaction Partners

Human XiAP Associated Factor 1 (XAF1) interaction partners

  1. Taken together, our results suggest that ROS (show ROS1 ELISA Kits) generation might be a predisposing event in berberine-induced mitochondrial apoptosis in EBV-transformed B cells through the upregulation of XAF1 and GADD45alpha (show GADD45A ELISA Kits) expression by MAPK (show MAPK1 ELISA Kits) and functional p53 (show TP53 ELISA Kits).

  2. Expression of XAF1 and TAp73 (show TP73 ELISA Kits) was also upregulated in casticin-treated T24 cells.

  3. Data show that X-linked inhibitor of apoptosis protein (XIAP (show XIAP ELISA Kits)) mRNA and protein expression increased, whereas XIAP-associated factor 1 (XAF1) mRNA and protein expression decreased with the growth of radiation dose and exposure time.

  4. the present study was the first to construct an adenovirus which coexpressed XAF1 and TNFalpha (show TNF ELISA Kits) in the same open reading frame and expressed them proportionally. As AdXAF1&TNFalpha (show TNF ELISA Kits) inhibited HCC (show FAM126A ELISA Kits) cells with enhanced efficiency, it may be applicable for the treatment of HCC (show FAM126A ELISA Kits).

  5. SHC1 (show SHC1 ELISA Kits) regulates the alternative splicing of XAF1 in extracellular matrix-detachment induced autophagy to coordinate with the anoikic cell death.

  6. Our study identified a novel splice variant of XAF1 in cancer cells

  7. Underexpression of XAF1 confers cisplatin-resistance in ovarian carcinoma.

  8. Restored XAF1 expression inhibits cell proliferation and induces cell apoptosis in human lung adenocarcinoma cell line A549. Furthermore, XAF1 may activate associated apoptotic signaling pathways in A549 cell line.

  9. Up-regulation of XAF1 distinctly increased apoptosis in colorectal cancer cells administered cisplatin.

  10. XAF1 stimulates HIPK2 (show HIPK2 ELISA Kits)-mediated Ser (show SIGLEC1 ELISA Kits)-46 phosphorylation of p53 (show TP53 ELISA Kits) and XAF1 also steps up the termination of p53 (show TP53 ELISA Kits)-mediated cell-cycle arrest by activating ZNF313 (show RNF114 ELISA Kits).

Mouse (Murine) XiAP Associated Factor 1 (XAF1) interaction partners

  1. Interferon gamma (show IFNG ELISA Kits) induces XAF1 and Noxa (show PMAIP1 ELISA Kits) expression and potentiates apoptosis by STAT3 (show STAT3 ELISA Kits) activation

  2. XAF1 possesses a potential antiangiogenesis effect. Suppressed expression of Tie-1 (show TIE1 ELISA Kits), Ang-1 (show ANGPT1 ELISA Kits), Ang-2 (show ANGPT2 ELISA Kits) and c-Myc (show MYC ELISA Kits) may be mechanistically responsible for the observed antiangiogenesis effect.

XAF1 Antigen Profile

Antigen Summary

This gene encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with XAF1

  • zgc:153893 (zgc:153893) antibody
  • XIAP associated factor 1 (XAF1) antibody
  • XIAP associated factor 1 (Xaf1) antibody
  • XIAP associated factor-1 (XAF1) antibody
  • BIRC4BP antibody
  • Fbxo39 antibody
  • HSXIAPAF1 antibody
  • XIAPAF1 antibody

Protein level used designations for XAF1

XIAP-associated factor 1 , BIRC4 binding protein , BIRC4-binding protein , F-box protein 39 , novel TRAF-type zinc finger protein

767709 Danio rerio
54739 Homo sapiens
327959 Mus musculus
509740 Bos taurus
679600 Rattus norvegicus
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