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This locus encodes a xylosyltransferase enzyme. Additionally we are shipping Xylosyltransferase I Kits (4) and and many more products for this protein.
Showing 10 out of 28 products:
Human Polyclonal XYLT1 Primary Antibody for EIA, WB - ABIN955606
Müller, Prante, Kleesiek, Götting: Identification and characterization of the human xylosyltransferase I gene promoter region. in The Journal of biological chemistry 2009
Show all 5 references for ABIN955606
Notch (show NOTCH1 Antibodies)-modifying xylosyltransferase structures support an SNi-like retaining mechanism.
We show that the pug (show MTHFD1 Antibodies) mutation disrupts Xylt1 activity and subcellular localization, leading to a reduction in GAG chains in pug (show MTHFD1 Antibodies) mutants. The pug (show MTHFD1 Antibodies) mutant serves as a novel model for mammalian dwarfism.
Human XYLT1 promoter sequence analysis and description.
These results suggest that XT-1 expression is refractory to the disease process and to inhibition by inflammatory cytokines and that signaling through AP-1, Sp1, and Sp3 is important in the maintenance of XT-1 levels in NP cells.
five distinct homozygous XYLT1 mutations may have a role in Desbuquois dysplasia type 2
A family study shows that functional alterations of XYLT1 cause an autosomal recessive short stature syndrome associated with intellectual disability.
XYLT1 activity increased time-dependently in response to progressive myofibroblast transformation.
AP-1 (show FOSB Antibodies) and Sp3 (show SP3 Antibodies) are key regulators of IL-1beta (show IL1B Antibodies)-mediated modulation of xylosyltransferase I expression.
Xylosyltransferase-I regulates glycosaminoglycan synthesis during the pathogenic process of human osteoarthritis
DXD motifs in human xylosyltransferase I are required for enzyme activity
Elevated XYLT1 activities in pseudoxanthoma elasticum patients is a marker of proteoglycan (show Vcan Antibodies) biosynthesis.
Over 80% of the nucleotide sequence of the XT-I-cDNA is necessary for expressing a recombinant enzyme with full catalytic activity.
This locus encodes a xylosyltransferase enzyme. The encoded protein catalyzes transfer of UDP-xylose to serine residues of an acceptor protein substrate. This transfer reaction is necessary for biosynthesis of glycosaminoglycan chains. Mutations in this gene have been associated with increased severity of pseudoxanthoma elasticum.
UDP-D-xylose:core protein beta-D-xylosyltransferase
, xylosyltransferase I
, peptide O-xylosyltransferase 1
, O-xylosyltransferase 1
, beta-D-xylosyltransferase 1
, xylosyltransferase 1
, xylosyltransferase iota
, protein xylosyltransferase