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Y Box Binding Protein 2 (YBX2) ELISA Kits

YBX2 encodes a nucleic acid binding protein which is highly expressed in germ cells. Additionally we are shipping YBX2 Antibodies (67) and YBX2 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human YBX2 YBX2 51087 Q9Y2T7
Anti-Rat YBX2 YBX2 303250  
Anti-Mouse YBX2 YBX2 53422  
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More ELISA Kits for YBX2 Interaction Partners

Human Y Box Binding Protein 2 (YBX2) interaction partners

  1. provides first evidence showing dbpC highly expressed in human testicular seminoma and ovarian dysgerminomas, and in carcinomas in other tissues and that its expression in normal tissues is nearly restricted to germ cells and placental trophoblasts

  2. transcriptional regulation of Contrin was investigated, and the promoter region between -272 and -253 relative to the transcription start site was shown to be critical for the manifestation of cell-type specific transcription

  3. A significant association between gene alterations in the YBX2 gene and abnormal spermatogenesis in humans, including a potential role in altering protamine expression, and implicate YBX2 gene alterations as a potential cause of male factor infertility.

  4. some polymorphisms of the MSY2 gene might be associated with impaired spermatogenesis and that the gene could also be involved in modifying the susceptibility to idiopathic spermatogenic impairment in humans

Mouse (Murine) Y Box Binding Protein 2 (YBX2) interaction partners

  1. homozygous double mutants could not be generated as haploinsufficiency of both Ybx2 and Ybx3 (show CSDA ELISA Kits) caused sterility characterized by extensive defects in spermatid differentiation.

  2. data suggest that MSY2 packages mRNAs in vivo with relatively little sequence specificity, which may lead to both stabilization and translation repression of maternal mRNAs

  3. binding of intact maternal mRNA by MSY2 is required for its cytoplasmic retention in oocytes

  4. role for MSY2 in stabilizing maternal mRNAs in growing oocytes

  5. MSY2 marks specific mRNAs in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay in meiotic and postmeiotic male germ cells of the mouse.

  6. Results suggest that Msy2 represents one of a small number of germ-cell-specific genes whose deletion leads to the disruption of both spermatogenesis and oogenesis.

  7. mRNA instability is a likely cause of the male infertility in Msy2-null mice.

  8. Study reports that CDC2A (CDK1 (show CDK1 ELISA Kits))-mediated phosphorylation of MSY2 triggers an abrupt transition in which most maternal mRNAs are significantly degraded.

  9. MSY2 and MSY4 (show CSDA ELISA Kits) bind a conserved sequence in the 3' untranslated region of protamine 1 (show PRM1 ELISA Kits) mRNA in vitro and in vivo

YBX2 Antigen Profile

Antigen Summary

This gene encodes a nucleic acid binding protein which is highly expressed in germ cells. The encoded protein binds to a Y-box element in the promoters of certain genes but also binds to mRNA transcribed from these genes. Pseudogenes for this gene are located on chromosome 10 and 15.

Gene names and symbols associated with YBX2

  • Y box binding protein 2 (YBX2) antibody
  • Y box binding protein 2 (ybx2) antibody
  • Y box binding protein 2 (LOC100346139) antibody
  • Y box binding protein 2 (Ybx2) antibody
  • Y box protein 2 (Ybx2) antibody
  • CONTRIN antibody
  • CSDA3 antibody
  • DBPC antibody
  • frgy2 antibody
  • Msy2 antibody
  • RGD1305068 antibody
  • YBX2 antibody

Protein level used designations for YBX2

Y box binding protein 2 , DNA-binding protein C , MSY2 homolog , Y-box-binding protein 2 , germ cell specific Y-box binding protein , germ cell-specific Y-box-binding protein , Y box protein 2 , FRGY2 homolog , Y-box protein MSY2

455231 Pan troglodytes
100170415 Xenopus (Silurana) tropicalis
100346139 Oryctolagus cuniculus
51087 Homo sapiens
489467 Canis lupus familiaris
614429 Bos taurus
303250 Rattus norvegicus
53422 Mus musculus
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