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YME1-Like 1 (S. Cerevisiae) Proteins (YME1L1)

The protein encoded by YME1L1 is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. Additionally we are shipping YME1-Like 1 (S. Cerevisiae) Antibodies (19) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse YME1L1 YME1L1 27377 O88967
YME1L1 10730 Q96TA2
Rat YME1L1 YME1L1 114217  
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Top YME1-Like 1 (S. Cerevisiae) Proteins at

Showing 3 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days

YME1L1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,

More Proteins for YME1-Like 1 (S. Cerevisiae) (YME1L1) Interaction Partners

Mouse (Murine) YME1-Like 1 (S. Cerevisiae) (YME1L1) interaction partners

  1. Data suggest that in a mouse model of neonatal hypoxic-ischemic brain injury, the expression of mitochondrial shaping proteins, such as OPA1 and Yme1L, are altered; in vitro and in vivo, OPA1 is cleaved to shorter forms and Yme1L expression is reduced.

  2. Constitutive OPA1 cleavage by YME1L and OMA1 (show OMA1 Proteins) at two distinct sites leads to the accumulation of both long and short forms of OPA1 and maintains mitochondrial fusion.

Human YME1-Like 1 (S. Cerevisiae) (YME1L1) interaction partners

  1. differential stress-induced degradation of YME1L and OMA1 (show OMA1 Proteins) as a mechanism for sensitively adapting mitochondrial inner membrane protease activity and function in response to distinct types of cellular insults.

  2. YME1L degradation reduces mitochondrial proteolytic capacity during oxidative stress.Loss of YME1L compromises the regulation of mitochondrial inner membrane proteostasis.

  3. Results reveal a crucial role for YME1L in the maintenance of mitochondrial inner-membrane proteostasis and in the proteolytic regulation of respiratory chain biogenesis.

YME1-Like 1 (S. Cerevisiae) (YME1L1) Protein Profile

Protein Summary

The protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with YME1L1

  • YME1-like 1 (S. cerevisiae) (Yme1l1)
  • YME1-like 1 ATPase (YME1L1)
  • YME1-like 1 ATPase (Yme1l1)
  • FTSH protein
  • FtsH1 protein
  • MEG4 protein
  • PAMP protein
  • YME1L protein

Protein level used designations for YME1L1

ATP-dependent metalloprotease FtsH1 , ATP-dependent zinc metalloprotease YME1L1 , YME1-like protein 1 , ATP-dependent metalloprotease FtsH1 homolog , ATP-dependent metalloprotease YME1L1 , meg-4 , presenilin-associated metalloprotease

27377 Mus musculus
10730 Homo sapiens
114217 Rattus norvegicus
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