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YTHDF3 encodes a member of the YTH (YT521-B homology) domain protein family. Additionally we are shipping YTH Domain Family, Member 3 Antibodies (23) and YTH Domain Family, Member 3 Proteins (2) and many more products for this protein.
These results indicate that together with YTHDF1 and YTHDF2 (show YTHDF2 ELISA Kits), YTHDF3 plays critical roles to accelerate metabolism of N(6)-methyladenosine -modified mRNAs in the cytoplasm.
The authors found that the overexpression of YTHDF proteins in cells inhibited HIV-1 infection mainly by decreasing HIV-1 reverse transcription, while knockdown of YTHDF1-3 in cells had the opposite effects. Moreover, silencing the N(6)-methyladenosine writers decreased HIV-1 Gag protein expression in virus-producing cells, while silencing the N(6)-methyladenosine erasers increased Gag expression.
This gene encodes a member of the YTH (YT521-B homology) domain protein family. The YTH domain is common in eukaryotes, is often found in the middle of the protein sequence, and may function in binding to RNA. Alternative splicing results in multiple transcript variants.
YTH domain family, member 3
, YTH domain family protein 3-like
, YTH domain family protein 3
, YTH domain family 3