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YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. Additionally we are shipping YY1 Transcription Factor Proteins (8) and YY1 Transcription Factor Kits (7) and many more products for this protein.
Showing 10 out of 149 products:
Human Polyclonal YY1 Primary Antibody for ChIP, WB - ABIN3434034
Baritaki, Huerta-Yepez, Sakai, Spandidos, Bonavida: Chemotherapeutic drugs sensitize cancer cells to TRAIL-mediated apoptosis: up-regulation of DR5 and inhibition of Yin Yang 1. in Molecular cancer therapeutics 2007
Show all 6 Pubmed References
Human Monoclonal YY1 Primary Antibody for WB - ABIN1882292
Burkard, Planyavsky, Kaupe, Breitwieser, Bürckstümmer, Bennett, Superti-Furga, Colinge: Initial characterization of the human central proteome. in BMC systems biology 2011
Show all 4 Pubmed References
Human Polyclonal YY1 Primary Antibody for IHC, IHC (p) - ABIN4366543
Bevelacqua, Bevelacqua, Candido, Skarmoutsou, Amoroso, Guarneri, Strazzanti, Gangemi, Mazzarino, DAmico, McCubrey, Libra, Malaponte: Nectin like-5 overexpression correlates with the malignant phenotype in cutaneous melanoma. in Oncotarget 2012
Show all 2 Pubmed References
Human Polyclonal YY1 Primary Antibody for ICC, IF - ABIN4366542
Soares, Cagnin, Chemello, Silvestrin, Musaro, De Pitta, Lanfranchi, Sandri: Involvement of microRNAs in the regulation of muscle wasting during catabolic conditions. in The Journal of biological chemistry 2014
Show all 2 Pubmed References
Human Monoclonal YY1 Primary Antibody for IF, IHC (p) - ABIN563397
Shin, Lee, Park, Kim, Ryu, Park, Yu, Jang: Gene expression profiling of human hepatoblastoma using archived formalin-fixed and paraffin-embedded tissues. in Virchows Archiv : an international journal of pathology 2011
Human Polyclonal YY1 Primary Antibody for WB - ABIN521441
Westendorp, Major, Nader, Salih, Leenen, Tuana: The E2F6 repressor activates gene expression in myocardium resulting in dilated cardiomyopathy. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012
YY1 is essential for Xenopus development in neural ectoderm differentiation, neural crest specification and directing neural crest mesenchyme formation by blocking slug
Yin Yang 1 transcription factor assembly into messenger ribonucleoprotein particles requires direct RNA binding activity
Results show that the YY1-RNA interaction is highly stable, and that YY1 possesses the ability to interact with structurally divergent RNA substrates.
results suggest that YY1a regulates PS receptor expression that linked to function of PSR (show JMJD6 Antibodies)-phagocyte mediated apoptotic cell engulfment during development
YY1 promotes zebrafish liver steatosis and lipotoxicity by inhibiting CHOP-10 (show DDIT3 Antibodies) expression.
Study demonstrated that beta-arrestin1 (show ARRB1 Antibodies) is critically involved in zebrafish primitive hematopoiesis, where beta-arrestin1 (show ARRB1 Antibodies) binds to and sequesters the PcG recruiter YY1, thus relieving PcG-mediated repression of cdx4-hox (show MSH2 Antibodies) pathway.
Study shows that the ubiquitously expressed transcription factor Yin Yang 1 (YY1) contributes to enhancer-promoter structural interactions in a manner analogous to DNA interactions mediated by CTCF (show CTCF Antibodies).
YY1 was over-expressed in RA which can bind to the promotor of IL-6 (show IL6 Antibodies) to introduce IL-6 (show IL6 Antibodies) expression, contributing to the inflammation of RA via stimulation of Th17 differentiation.
YY1 promotes apoptosis via upregulating Bax (show BAX Antibodies) transcription and subsequent activation of Bax (show BAX Antibodies) by translocation from the cytosol to the mitochondrial membrane.
High YY1 expression is associated with Lung Cancer Progression.
Low YY1 expression is associated with pancreatic ductal adenocarcinoma.
PRE-PIK3C2B interacts directly with YY1 in vitro and recruits PRC2 complex in vivo. The localization of PcG proteins including YY1 to PRE-PIK3C2B in HEK cells is decreased on knock-down of either YY1 or SUZ12.
YY1 promotes mTORC2 (show CRTC2 Antibodies)-mediated AKT (show AKT1 Antibodies) activation
Yin Yang 1 (YY1) interacts with Seryl-tRNA synthetase (SerRS (show SARS Antibodies)) to form a SerRS (show SARS Antibodies)/YY1 complex which functions as a negative effector to regulate vegfa (show VEGFA Antibodies) transcription through binding a distal segment of the vegfa (show VEGFA Antibodies) promoter, while NFKB1 (show NFKB1 Antibodies) serves as a positive effector through outcompeting SerRS (show SARS Antibodies)/YY1 for binding at the same distal segment.
these results define a clinical syndrome caused by haploinsufficiency of YY1 through dysregulation of key transcriptional regulators.
Interactions of the chromatin remodeling protein INO80 (show INO80 Antibodies) with DNA, and the role of YY1 in this process have been described.
these results suggested that the basal promoter activity of the mIRF-3 gene is regulated by transcription factors Egr2 (show EGR2 Antibodies) and YY1 in NIH3T3 cells
DNA binding domain of YY1 is necessary for X-chromosome inactivation in activated B cells, as ex-vivo YY1 deletion results in loss of inactive X (Xi) chromosome heterochromatin marks and up-regulation of X-linked genes.
Transcriptome analysis revealed that YY1 is required for mitochondrial gene expression, and ultrastructural analysis confirmed compromised mitochondrial integrity in the mutant intestine.
regulates broad general processes throughout all stages of B-cell differentiation: normally activates genes involved in mitochondrial bioenergetics; normally down-regulates genes involved in transcription, mRNA splicing, NF-kappaB (show NFKB1 Antibodies) signaling pathways, the AP-1 (show JUN Antibodies) transcription factor network, chromatin remodeling, cytokine signaling pathways, cell adhesion, and cell proliferation
Results indicate that YY1 plays an important role in regulating the balance between dark zone and light zone cells in germinal center (GCs (show UGCG Antibodies)) and between survival and death of GC B (show NPR2 Antibodies) cells.
YY1 is required for germinal center B cell development.
Dp71 (show DMD Antibodies) expression in hepatic cells is carried out, in part, by YY1-, Sp1 (show SP1 Antibodies)- and Sp3 (show SP3 Antibodies)-mediated transcription from the Dp71 (show DMD Antibodies) promoter.
this study shows that YY1 regulates the formation of terminal-effector CD8 (show CD8A Antibodies)+ T cell fates
that yin yang 1 strongly localizes in the spermatogonial stem cells and co-localizes heterogeneously with CP2c to permit spermatogenesis
YY1 and SP1 (show SP1 Antibodies) independently and cooperatively govern the Mesp1 (show MESP1 Antibodies) expression during embryogenesis.
YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.
YY1 transcription factor
, YY1 transcription factor, like
, transcription factor YY1
, Yin Yang 1
, INO80 complex subunit S
, Yin and Yang 1 protein
, delta transcription factor
, transcriptional repressor protein YY1
, GLI-Krupple related protein
, UCR-motif DNA-binding protein
, UCRBP transcription factor
, yin and yang 1