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anti-Z-DNA Binding Protein 1 (ZBP1) Antibodies

ZBP1 encodes a Z-DNA binding protein. Additionally we are shipping Z-DNA Binding Protein 1 Proteins (9) and Z-DNA Binding Protein 1 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ZBP1 303477 Q8CGX0
ZBP1 81030 Q9H171
ZBP1 58203 Q9QY24
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Top anti-Z-DNA Binding Protein 1 Antibodies at antibodies-online.com

Showing 10 out of 55 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of ZBP1 in human small intestine tissue with ZBP1 antibody at 2.5 μg/ml. Western blot analysis of ZBP1 in mouse small intestine tissue lysate with ZBP1 antibody at (A) 0.5, (B) 1 and (C) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Mouse Un-conjugated IP, WB Western Blot analysis of mouse ZBP1 in L929 cells by using anti-ZBP1, mAb (Zippy-1) . Cell extracts from L929 cell either unstimulated (lane 1) or stimulated for 24h with poly(dA.dT) poly(dT.dA) at 3μg/ml (lane 2) were resolved by SDS-PAGE under reducing conditions, transferred to nitrocellulose and incubated with the anti-ZBP1, mAb (Zippy-1) at a 1:1000 dilution for 1 hour. Proteins were visualized using a peroxidase-conjugated polyclonal antibody to mouse IgG and a chemiluminescence detection system. The multiple bands represent isoforms or degradation products of ZBP1 since they are down regulated upon ZBP1 siRNA treatment (data not shown). 100 μg Log in to see 5 to 8 Days
$393.75
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rat Un-conjugated FACS 100 μg Log in to see 10 to 12 Days
$298.95
Details
Human Rabbit Un-conjugated WB ZBP1 antibody used at 5 ug/ml to detect target protein. 100 μg Log in to see 3 to 4 Days
$388.93
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Liver (formalin-fixed, paraffin-embedded) stained with ZBP1 antibody ABIN351453 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 15 to 19 Days
$455.07
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB 50 μg Log in to see 3 to 4 Days
$186.35
Details

ZBP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)


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Top referenced anti-Z-DNA Binding Protein 1 Antibodies

  1. Human Monoclonal ZBP1 Primary Antibody for FACS - ABIN2666378 : Deigendesch, Koch-Nolte, Rothenburg: ZBP1 subcellular localization and association with stress granules is controlled by its Z-DNA binding domains. in Nucleic acids research 2006 (PubMed)
    Show all 3 references for ABIN2666378

  2. Human Polyclonal ZBP1 Primary Antibody for ELISA, WB - ABIN1003496 : Schwartz, Behlke, Lowenhaupt, Heinemann, Rich: Structure of the DLM-1-Z-DNA complex reveals a conserved family of Z-DNA-binding proteins. in Nature structural biology 2001 (PubMed)
    Show all 3 references for ABIN1003496

  3. Human Polyclonal ZBP1 Primary Antibody for IHC (p), ELISA - ABIN2473228 : Jan, Revel: Hemocyanin - antibody labeling of phodopsin in mouse retina for a scanning electron microscope study. in Journal of supramolecular structure 1975 (PubMed)
    Show all 2 references for ABIN2473228

  4. Human Polyclonal ZBP1 Primary Antibody for WB - ABIN2774646 : Rothenburg, Schwartz, Koch-Nolte, Haag: Complex regulation of the human gene for the Z-DNA binding protein DLM-1. in Nucleic acids research 2002 (PubMed)

More Antibodies against Z-DNA Binding Protein 1 Interaction Partners

Pig (Porcine) Z-DNA Binding Protein 1 (ZBP1) interaction partners

  1. These results indicate that DAI is an important immuno-regulator of the porcine innate immune system

Human Z-DNA Binding Protein 1 (ZBP1) interaction partners

  1. Our results show that HSV2 is detected by a plethora of PRRs including DAI protein which trigger cytokine secretion to protect the host.

  2. DAI could function as a DNA sensor and a regulator in DNA-induced macrophage M2b polarization and lupus nephritis.

  3. Collectively, these results demonstrate that DAI can suppress HSV-1 growth independent of DNA sensing through mechanisms involving suppression of viral genomes and regulation of ICP0.

  4. these data indicate that ZBP1 (show IGF2BP1 Antibodies) may function as an adapter to export the Ro/Y3 RNA complex from nuclei.

  5. Solution structure of the Zbeta domain of human DNA-dependent activator of IFN-regulatory factors and its binding modes to B (show TDO2 Antibodies)- and Z-DNAs.

  6. hZbeta(DAI) binds to Z-DNA via an active-di B-Z transition mechanism.

  7. These results suggest that activation of DAI might contribute to augment HIV-1 replication through DAI- NF-kappaB (show NFKB1 Antibodies) pathway.

  8. identify ZBP1 (show IGF2BP1 Antibodies) as being essential for IRF3 (show IRF3 Antibodies) activation and interferon beta (show IFNB1 Antibodies) expression triggered by HCMV, as well as being sufficient to enhance HCMV-stimulated beta interferon (show IFNA Antibodies) transcription and secretion.

  9. Z-DNA binding activities of two Zalpha domains in the human ZBP1 (show IGF2BP1 Antibodies), hZalpha(ZBP1 (show IGF2BP1 Antibodies)) and hZbeta(ZBP1 (show IGF2BP1 Antibodies))were characterized.

  10. In conclusion, intracellular bacteria and cytosolic poly(dA-dT) activate IFNbeta responses in different human cells without requiring human ZBP1 (show IGF2BP1 Antibodies).

Mouse (Murine) Z-DNA Binding Protein 1 (ZBP1) interaction partners

  1. DAI as an important cytosolic DNA sensor, is responsible for the recognition of A/T or G/C-rich DNA derived from DNA virus.

  2. Disruption of the in vivo interaction of KIF11 (show KIF11 Antibodies) with ZBP1 delocalizes beta-actin (show ACTB Antibodies) mRNA and affects cell migration.

  3. Association of ribosomes and ZBP1 with the mRNA were anti-correlated both near the nucleus of primary fibroblasts and neurons and in peripheral cellular regions such as the leading edge of fibroblasts, therefore validating the hypothesis that ZBP1 spatially regulates beta-actin (show ACTB Antibodies) mRNA localized translation.

  4. DAI interacts with RIP3 (show MPRIP Antibodies) to mediate virus-induced necrosis analogous to the RIP1 (show RALBP1 Antibodies)-RIP3 (show MPRIP Antibodies) complex controlling death receptor-induced necroptosis.

  5. data support a direct role for ZBP1 in transport and translation of mRNA cargos in axonal regeneration in vitro and in vivo

  6. observations underscore an integral role of DAI (DLM-1/ZBP1) in the DNA-mediated activation of innate immune responses

  7. mechanism of DAI activation and the complex regulatory mechanisms underlying DNA-mediated protective and pathologic immune responses.

Z-DNA Binding Protein 1 (ZBP1) Antigen Profile

Protein Summary

This gene encodes a Z-DNA binding protein. The encoded protein plays a role in the innate immune response by binding to foreign DNA and inducing type-I interferon production. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with ZBP1

  • Z-DNA binding protein 1 (ZBP1) antibody
  • insulin-like growth factor 2 mRNA binding protein 1 (Igf2bp1) antibody
  • Z-DNA binding protein 1 (Zbp1) antibody
  • 2010010H03Rik antibody
  • C20orf183 antibody
  • Dai antibody
  • DLM-1 antibody
  • Dlm1 antibody
  • Imp1 antibody
  • mZaDLM antibody
  • ZBP1 antibody

Protein level used designations for ZBP1

Z-DNA binding protein 1 , tumor stroma and activated macrophage protein DLM-1 , DNA-dependent activator of IFN-regulatory factor , Z-DNA-binding protein 1 , B-actin zipcode-binding protein 1 , IGF-II mRNA-binding protein 1 , IGF2 mRNA-binding protein 1 , IMP-1 , VICKZ family member 1 , insulin-like growth factor 2 binding protein 1 , insulin-like growth factor 2 mRNA-binding protein 1 , insulin-like growth factor 2, binding protein 1 , rZBP-1 , zipcode-binding protein-1 , DNA-dependent activator of IFN-regulatory factors , DNA-dependent activator of IRFs , DNA-dependent activator of interferon regulatory factors

GENE ID SPECIES
508333 Bos taurus
696090 Macaca mulatta
746148 Pan troglodytes
100144524 Sus scrofa
303477 Rattus norvegicus
81030 Homo sapiens
58203 Mus musculus
171091 Rattus norvegicus
100734114 Cavia porcellus
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