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ZFP36L1 is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. Additionally we are shipping ZFP36 Ring Finger Protein-Like 1 Proteins (4) and ZFP36 Ring Finger Protein-Like 1 Kits (1) and many more products for this protein.
Showing 10 out of 79 products:
Human Monoclonal ZFP36L1 Primary Antibody for WB - ABIN393989
Dubois, Trynka, Franke, Hunt, Romanos, Curtotti, Zhernakova, Heap, Adány, Aromaa, Bardella, van den Berg, Bockett, de la Concha, Dema, Fehrmann, Fernández-Arquero, Fiatal, Grandone, Green, Groen et al.: Multiple common variants for celiac disease influencing immune gene expression. ... in Nature genetics 2010
Show all 5 references for ABIN393989
Mouse (Murine) Polyclonal ZFP36L1 Primary Antibody for WB - ABIN1882008
Takahashi, Tada, Mihara: RNA aptamers selected against amyloid beta-peptide (Abeta) inhibit the aggregation of Abeta. in Molecular bioSystems 2009
Show all 5 references for ABIN1882008
Cow (Bovine) Polyclonal ZFP36L1 Primary Antibody for WB - ABIN2777899
Blackshear, Phillips, Vazquez-Matias, Mohrenweiser: Polymorphisms in the genes encoding members of the tristetraprolin family of human tandem CCCH zinc finger proteins. in Progress in nucleic acid research and molecular biology 2003
Cow (Bovine) Polyclonal ZFP36L1 Primary Antibody for WB - ABIN2780624
Ciais, Cherradi, Bailly, Grenier, Berra, Pouyssegur, Lamarre, Feige: Destabilization of vascular endothelial growth factor mRNA by the zinc-finger protein TIS11b. in Oncogene 2004
Dog (Canine) Polyclonal ZFP36L1 Primary Antibody for WB - ABIN2777900
Rual, Venkatesan, Hao, Hirozane-Kishikawa, Dricot, Li, Berriz, Gibbons, Dreze, Ayivi-Guedehoussou, Klitgord, Simon, Boxem, Milstein, Rosenberg, Goldberg, Zhang, Wong, Franklin, Li, Albala, Lim et al.: Towards a proteome-scale map of the human protein-protein interaction network. ... in Nature 2005
A ZFP36L1-mediated regulatory circuit through repressing CDK6 (show CDK6 Antibodies) expression.
Gene expression analysis revealed that three gene BACH2 (show BACH2 Antibodies), PTGER4 (show PTGER4 Antibodies) and ZFP36L1, are down-regulated in MS patients' blood cells compared to healthy subjects.
ZFP36L1 interacts with and mediates degradation of anti-apoptotic BCL2 (show BCL2 Antibodies) mRNA as its important target in malignant B-cells.
regulator of renal mineralocorticoid receptor abundance
NR4A2 (show NR4A2 Antibodies) expression is negatively regulated by zinc finger protein 36 (show ZKSCAN1 Antibodies), C3H1 (show ZFP36 Antibodies) type-like 1 (Zfp36l1).
The roles of TTP (show ADAMTS13 Antibodies) and BRF (show BRF1 Antibodies) proteins in regulated mRNA decay.
ZFP36L1 negatively regulates erythroid differentiation by directly binding the 3' untranslated region of Stat5b (show STAT5B Antibodies) encoding mRNA.
these results suggest an important role of ZFP36L1 in wound healing.
polymorphisms sequenced in genomic DNA encoding the TTP (show ADAMTS13 Antibodies) protein (ZFP36 (show ZFP36 Antibodies)) and those of its two known mammalian relatives, ZFP36L1 and ZFP36L2 (show ZFP36L2 Antibodies), from 72 to 92 anonymous human subjects from various geographical and ethnic backgrounds
Data suggest an important role for butyrate response factor-1 in osteoblasts within the molecular network of parathyroid hormone (show PTH Antibodies)-dependent bone remodeling.
ZFP36L1 and ZFP36L2 (show ZFP36L2 Antibodies) suppress an evolutionarily conserved posttranscriptional regulon consisting of messenger RNAs whose protein products cooperatively promote transition into the S phase of the cell cycle.
Myeloid ZFP36 (show ZFP36 Antibodies) may fully compensate for loss of ZFP36L1.
Challenging the renal osmotic gradient by submitting mice to water deprivation, diuretic administration, or high-Na(+) diet increased renal Tis11b and decreased mineralocorticoid receptor (show NR3C2 Antibodies) expression, particularly in the cortex.
Findings suggest that ZFP36L1 negatively regulates plasmacytoid differentiation, at least in part, by targeting the expression of BLIMP1 (show PRDM1 Antibodies).
Data revealed that ZFP36L1 and ZFP36L2 (show ZFP36L2 Antibodies) bound to the 3' untranslated region (UTR (show UTS2R Antibodies)) of MAPK phosphatase-1 (MKP-1 (show DUSP1 Antibodies)) mRNA and downregulated Mkp-1 (show DUSP1 Antibodies) 3'UTR (show UTS2R Antibodies)-mediated luciferase activity.
I postulate that the embryonic arrest linked to the DeltaN-Zfp36l2 (show ZFP36L2 Antibodies) truncation might be related to its resistance to stimulus-induced down-regulation.
ZFP36L1 has a critical role in lymphocyte development and may function as a tumor suppressor.
Results suggest that lack of Zfp36L1 expression during mid-gestation results in the abnormal stabilization of one or more mRNAs whose encoded proteins lead directly or indirectly to abnormal placentation and fetal death.
This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
CCCH zinc finger protein C3H-2
, zinc finger protein 36, C3H type-like 1
, EGF-response factor 1
, butyrate response factor 1
, early response factor Berg36
, zinc finger protein 36, C3H1 type-like 1
, zinc finger protein, C3H type, 36-like 1
, EGF-inducible protein CMG1