ZFP57 Zinc Finger Protein (ZFP57) ELISA Kits

The protein encoded by ZFP57 is a zinc finger protein containing a KRAB domain.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human ZFP57 ZFP57 346171 Q9NU63
Anti-Mouse ZFP57 ZFP57 22715 Q8C6P8
Anti-Rat ZFP57 ZFP57 361783 A0JPK3
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More ELISA Kits for ZFP57 Zinc Finger Protein Interaction Partners

Human ZFP57 Zinc Finger Protein (ZFP57) interaction partners

  1. transient neonatal diabetes type 1 is associated with ZFP57 mutations

  2. ZFP57 regulates the expression of insulin-like growth factor 2 (IGF2 (show IGF2 ELISA Kits)), which has a critical role in ZFP57-induced anchorage-independent growth

  3. High grade glioblastoma is associated with increased level of ZFP57, a protein involved in gene imprinting, and aberrant expression of CPT1A (show CPT1A ELISA Kits) and CPT1C (show CPT1C ELISA Kits).

  4. These data identify ZFP57 as a candidate gene underlying reported MHC disease associations, notably for putative regulatory variants associated with cancer and HIV-1.

  5. Mouse and human ZFP57 are orthologs despite relatively low sequence identity.

  6. ZFP57 vZFP57 vZFP57

  7. no evidence for ZFP57 alterations as a major cause in sporadic Beckwith-Wiedemann Syndrome cases

  8. this study does not provide evidence that ZFP57 mutations are the cause of 11p15-hypomethylation in Silver-Russell syndrome (SRS (show SMS ELISA Kits)) patients and contribute to the aetiology of SRS (show SMS ELISA Kits)

  9. Study reports mutations in ZFP57, which encodes a zinc-finger transcription factor (show OSR1 ELISA Kits) expressed in early development, in seven pedigrees with a shared pattern of mosaic hypomethylation and a conserved range of clinical features.

Mouse (Murine) ZFP57 Zinc Finger Protein (ZFP57) interaction partners

  1. A group of functionally significant composite DNA elements (ZFP57 binding site (ZFBS)-Morph overlaps) that may play dual roles in the regulation of allele-specific gene expression.

  2. another function of ZFP57 in early embryogenesis is to repress cis (show CISH ELISA Kits)-acting regulatory elements whose activity is not yet required.

  3. Data show that ZFP57 binding is affected by single nucleotide polymorphism (SNPs) and closely associated TGCCGC motif sequences that are present at the target sites.

  4. Within established mouse imprinted clusters, ZFP57 specifically binds known or predicted imprinting control region elements, but does not interact with secondary somatically differentially methylated regions (DMRs) or germline DMRs that are not imprinting controlling.

  5. ZFP57 may modulate NOTCH (show NOTCH1 ELISA Kits) signaling during cardiac development.

  6. Taken together, our results suggest that Nanog (show NANOG ELISA Kits) positively regulates Zfp57 expression in multiple types of cells.

  7. Mouse and human ZFP57 are orthologs despite relatively low sequence identity.

  8. Data suggest that Glu182 in the DNA binding site in zinc finger motif of Zfp57 plays important role in binding specificity and affinity for 5-carboxylcytosine and other cytosine analogs.

  9. the structure of the DNA-binding domain of Zfp57, consisting of two adjacent zinc fingers, in complex with fully methylated DNA

  10. ZFP57 may recruit DNA methyltransferases to its target regions to maintain DNA methylation (show HELLS ELISA Kits) imprint, and this interaction is likely facilitated by KAP1/TRIM28/TIF1beta (show TRIM28 ELISA Kits).

ZFP57 Zinc Finger Protein (ZFP57) Antigen Profile

Antigen Summary

The protein encoded by this gene is a zinc finger protein containing a KRAB domain. Studies in mouse suggest that this protein may function as a transcriptional repressor. Mutations in this gene have been associated with transient neonatal diabetes mellitus type 1 (TNDM1).

Gene names and symbols associated with ZFP57

  • ZFP57 zinc finger protein (ZFP57) antibody
  • zinc finger protein 57 (Zfp57) antibody
  • bA145L22 antibody
  • bA145L22.2 antibody
  • C6orf40 antibody
  • G19 antibody
  • TNDM1 antibody
  • Zfp-57 antibody
  • ZNF698 antibody

Protein level used designations for ZFP57

zfp-57 , zinc finger protein 57 homolog , zinc finger protein 698 , KRAB box-like

346171 Homo sapiens
786262 Bos taurus
22715 Mus musculus
361783 Rattus norvegicus
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