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The protein encoded by ZFP91 is a member of the zinc finger family of proteins. Additionally we are shipping ZFP91 Antibodies (63) and ZFP91 Proteins (2) and many more products for this protein.
ZFP91 is overexpressed in prostate cancer.
hHgher protein levels of ZFP91 in all cancer cell lines.
These data clearly indicate that ZFP91 is a key regulator in LIGHT-induced activation of non-canonical NF-kappaB pathway in LTbetaR signaling.
An atypical E3 ligase zinc finger protein 91 stabilizes and activates NF-kappaB (show NFKB1 ELISA Kits)-inducing kinase via Lys63-linked ubiquitination.
likely to play an important role in cell proliferation and/or anti-apoptosis, and may serve as a molecular marker for AML (show RUNX1 ELISA Kits)
Functional analysis of the human ZFP91 protein.
The protein encoded by this gene is a member of the zinc finger family of proteins. The gene product contains C2H2-type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. This protein functions as a regulator of the non-canonical NF-kappaB pathway in lymphotoxin-beta receptor signaling. Alternative splicing results in multiple transcript variants. A read-through transcript variant composed of ZFP91 and the downstream CNTF gene sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. A ZFP91-related pseudogene has also been identified on chromosome 2.
E3 ubiquitin-protein ligase ZFP91
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, zinc finger protein homologous to Zfp91 in mouse
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