Zinc Finger, AN1-Type Domain 2B (ZFAND2B) ELISA Kits

ZFAND2B encodes a protein containing AN1-type zinc-fingers and ubiquitin-interacting motifs. Additionally we are shipping Zinc Finger, AN1-Type Domain 2B Antibodies (36) and Zinc Finger, AN1-Type Domain 2B Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse ZFAND2B ZFAND2B 68818 Q91X58
Anti-Rat ZFAND2B ZFAND2B 363253 Q4KLG9
Anti-Human ZFAND2B ZFAND2B 130617 Q8WV99
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More ELISA Kits for Zinc Finger, AN1-Type Domain 2B Interaction Partners

Mouse (Murine) Zinc Finger, AN1-Type Domain 2B (ZFAND2B) interaction partners

  1. Study demonstrates specificity of AIRAPL for Lys48-linked tri-ubiquitin chains triggered by intrinsic selectivity of its double-sided UIM (UIM2) for Lys48 linkage and a flexible inter-UIM linker that results in an overall conformation which confers simultaneous binding of tUIMs to three consecutive ubiquitin moieties in a Lys48-linked chain.

  2. AIRAPL-deficient mice develop a fully-penetrant myeloproliferative neoplastic process via dysregulation of IGF1/IGF1R.

Human Zinc Finger, AN1-Type Domain 2B (ZFAND2B) interaction partners

  1. Results demonstrate that on specific translocation inhibition, a p97 (show EIF4G2 ELISA Kits)-AIRAPL complex directly binds and regulates the efficient processing of polyubiquitinated pQC substrates by the UPS. Results also demonstrate p97 (show EIF4G2 ELISA Kits)'s role in pQC processing of preproinsulin (show INS ELISA Kits) in cases of naturally occurring mutations within the signal sequence of insulin (show INS ELISA Kits).

  2. Consistent with its proposed role as a tumor suppressor of myeloid transformation, AIRAPL expression is widely abrogated in human myeloproliferative disorders.

  3. AIRAPL binds to p97 (show EIF4G2 ELISA Kits) and forms a complex in the endoplasmic reticulum membrane.

  4. An AIP-1 (show BIRC3 ELISA Kits) human homologue, ZFAND2B, has a similar protective effect against Abeta (show APP ELISA Kits) toxicity.

Zinc Finger, AN1-Type Domain 2B (ZFAND2B) Antigen Profile

Antigen Summary

This gene encodes a protein containing AN1-type zinc-fingers and ubiquitin-interacting motifs. The encoded protein likely associates with the proteosome to stimulate the degradation of toxic or misfolded proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with ZFAND2B

  • zinc finger, AN1 type domain 2B (Zfand2b) antibody
  • zinc finger, AN1-type domain 2B (ZFAND2B) antibody
  • 1110060O18Rik antibody
  • AIRAPL antibody
  • C81256 antibody
  • RGD1306260 antibody

Protein level used designations for ZFAND2B

AIRAP-like protein , AN1-type zinc finger protein 2B , arsenite-inducible RNA-associated protein-like protein

GENE ID SPECIES
68818 Mus musculus
363253 Rattus norvegicus
130617 Homo sapiens
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