Zinc Finger, AN1-Type Domain 2B Proteins (ZFAND2B)

ZFAND2B encodes a protein containing AN1-type zinc-fingers and ubiquitin-interacting motifs. Additionally we are shipping Zinc Finger, AN1-Type Domain 2B Antibodies (35) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse ZFAND2B ZFAND2B 68818 Q91X58
ZFAND2B 363253 Q4KLG9
ZFAND2B 130617 Q8WV99
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Top Zinc Finger, AN1-Type Domain 2B Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
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Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,663.83
Details

ZFAND2B Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Human , ,
, ,

More Proteins for Zinc Finger, AN1-Type Domain 2B (ZFAND2B) Interaction Partners

Mouse (Murine) Zinc Finger, AN1-Type Domain 2B (ZFAND2B) interaction partners

  1. Study demonstrates specificity of AIRAPL for Lys48-linked tri-ubiquitin chains triggered by intrinsic selectivity of its double-sided UIM (UIM2) for Lys48 linkage and a flexible inter-UIM linker that results in an overall conformation which confers simultaneous binding of tUIMs to three consecutive ubiquitin moieties in a Lys48-linked chain.

  2. AIRAPL-deficient mice develop a fully-penetrant myeloproliferative neoplastic process via dysregulation of IGF1/IGF1R.

Human Zinc Finger, AN1-Type Domain 2B (ZFAND2B) interaction partners

  1. Results demonstrate that on specific translocation inhibition, a p97 (show EIF4G2 Proteins)-AIRAPL complex directly binds and regulates the efficient processing of polyubiquitinated pQC substrates by the UPS. Results also demonstrate p97 (show EIF4G2 Proteins)'s role in pQC processing of preproinsulin (show INS Proteins) in cases of naturally occurring mutations within the signal sequence of insulin (show INS Proteins).

  2. Consistent with its proposed role as a tumor suppressor of myeloid transformation, AIRAPL expression is widely abrogated in human myeloproliferative disorders.

  3. AIRAPL binds to p97 (show EIF4G2 Proteins) and forms a complex in the endoplasmic reticulum membrane.

  4. An AIP-1 (show BIRC3 Proteins) human homologue, ZFAND2B, has a similar protective effect against Abeta (show APP Proteins) toxicity.

Zinc Finger, AN1-Type Domain 2B (ZFAND2B) Protein Profile

Protein Summary

This gene encodes a protein containing AN1-type zinc-fingers and ubiquitin-interacting motifs. The encoded protein likely associates with the proteosome to stimulate the degradation of toxic or misfolded proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with ZFAND2B

  • zinc finger, AN1 type domain 2B (Zfand2b)
  • zinc finger, AN1-type domain 2B (ZFAND2B)
  • 1110060O18Rik protein
  • AIRAPL protein
  • C81256 protein
  • RGD1306260 protein

Protein level used designations for ZFAND2B

AIRAP-like protein , AN1-type zinc finger protein 2B , arsenite-inducible RNA-associated protein-like protein

GENE ID SPECIES
68818 Mus musculus
363253 Rattus norvegicus
130617 Homo sapiens
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