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Zinc Finger, CCHC Domain Containing 11 (ZCCHC11) ELISA Kits

ZCCHC11 is an RNA uridyltransferase (EC 2.7.7.52) that uses UTP to add uridines to the 3-prime end of substrate RNA molecules (Jones et al., 2009 [PubMed 19701194]).[supplied by OMIM, Jan 2011].. Additionally we are shipping Zinc Finger, CCHC Domain Containing 11 Antibodies (47) and Zinc Finger, CCHC Domain Containing 11 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human ZCCHC11 ZCCHC11 23318 Q5TAX3
Anti-Mouse ZCCHC11 ZCCHC11 230594 B2RX14
Anti-Rat ZCCHC11 ZCCHC11 313481  
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More ELISA Kits for Zinc Finger, CCHC Domain Containing 11 Interaction Partners

Human Zinc Finger, CCHC Domain Containing 11 (ZCCHC11) interaction partners

  1. Data indicate that some of the small molecules were validated as specific inhibitors of 3' terminal uridylyl transferase (TUTase (show TUT1 ELISA Kits)) Zcchc11 (TUT4) activity.

  2. Study identified TUT4 and TUT7 as uridylyl transferases for poly(A)+ mRNAs in humans and delineated in detail the action mechanism and molecular function of uridylation in the mRNA decay pathway.

  3. miR (show MLXIP ELISA Kits)-26a directly targets Lin28B (show LIN28B ELISA Kits) and Zcchc11-two critical repressors of let-7 maturation.

  4. Study identified TUT7, TUT4, and TUT2 as novel components of the miRNA biogenesis pathway.

  5. Lin28 (show LIN28A ELISA Kits) uses two different TUTases to control let-7 expression .

  6. Terminal uridyltransferase enzyme Zcchc11 promotes cell proliferation independent of its uridyltransferase activity

  7. TUT4 adds an oligouridine tail to the pre-let-7, which blocks Dicer (show DICER1 ELISA Kits) processing. Knockdown of TUT4 and Lin28 (show LIN28A ELISA Kits) reduces the level of stem cell markers

  8. We propose that ZCCHC11 is a unique TLR signal regulator, which interacts with TIFA (show IL22 ELISA Kits) after LPS (show IRF6 ELISA Kits) treatment and suppresses the TRAF6 (show TRAF6 ELISA Kits)-dependent activation of NF-kappaB (show NFKB1 ELISA Kits).

  9. Zcchc11 fine tunes IL-6 (show IL6 ELISA Kits) production by uridylating miR (show MLXIP ELISA Kits)-26a.

Mouse (Murine) Zinc Finger, CCHC Domain Containing 11 (ZCCHC11) interaction partners

  1. We conclude that the Zcchc11-mediated terminal uridylation of mature miRNAs is pervasive and physiologically significant, especially important in the neonatal period for fostering IGF-1 (show IGF1 ELISA Kits) expression and enhancing postnatal growth and survival

  2. We propose that ZCCHC11 is a unique TLR signal regulator, which interacts with TIFA (show TIFA ELISA Kits) after LPS (show TLR4 ELISA Kits) treatment and suppresses the TRAF6 (show TRAF6 ELISA Kits)-dependent activation of NF-kappaB (show NFKB1 ELISA Kits).

  3. Zcchc11 fine tunes IL-6 (show IL6 ELISA Kits) production by uridylating miR (show MLXIP ELISA Kits)-26a.

  4. Lin28 (show LIN28A ELISA Kits) recruits the TUTase (show TUT1 ELISA Kits) Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells

Zinc Finger, CCHC Domain Containing 11 (ZCCHC11) Antigen Profile

Antigen Summary

ZCCHC11 is an RNA uridyltransferase (EC 2.7.7.52) that uses UTP to add uridines to the 3-prime end of substrate RNA molecules (Jones et al., 2009

Gene names and symbols associated with ZCCHC11

  • zinc finger, CCHC domain containing 11 (ZCCHC11) antibody
  • zinc finger, CCHC domain containing 11 (zcchc11) antibody
  • Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) (SMG5) antibody
  • smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) (SMG5) antibody
  • Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) (smg5) antibody
  • terminal uridylyltransferase 4-like (LOC528986) antibody
  • zinc finger, CCHC domain containing 11 (Zcchc11) antibody
  • 6030404K05Rik antibody
  • 9230115F04Rik antibody
  • DKFZp459G145 antibody
  • mKIAA0191 antibody
  • PAPD3 antibody
  • PPAPD3 antibody
  • TUT4 antibody
  • wu:fc06h08 antibody
  • wu:fy37g11 antibody
  • ZCCHC11 antibody
  • zgc:113841 antibody

Protein level used designations for ZCCHC11

zinc finger, CCHC domain containing 11 , TUTase4 , Caffeine Induced Death (S. pombe Cid) homolog family member (cid-1)-like , terminal uridylyltransferase 4-like , Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) , Est1p-like protein B , protein SMG5 , SMG5 homolog nonsense mediated mRNA decay factor , terminal uridylyltransferase 4 , PAP associated domain containing 3 , TUTase 4 , zinc finger CCHC domain-containing protein 11

GENE ID SPECIES
100294536 Pongo abelii
323683 Danio rerio
424642 Gallus gallus
456859 Pan troglodytes
100050669 Equus caballus
100141500 Xenopus (Silurana) tropicalis
100355629 Oryctolagus cuniculus
100406726 Callithrix jacchus
100484245 Ailuropoda melanoleuca
100516979 Sus scrofa
425473 Gallus gallus
457390 Pan troglodytes
490414 Canis lupus familiaris
553261 Danio rerio
100558341 Anolis carolinensis
100599356 Nomascus leucogenys
528986 Bos taurus
23318 Homo sapiens
475349 Canis lupus familiaris
230594 Mus musculus
313481 Rattus norvegicus
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