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Palmitoyl acyltransferase for the G-protein coupled receptor SSTR5 and for FLOT2 (By similarity). Additionally we are shipping ZDHHC5 Antibodies (14) and and many more products for this protein.
PLM palmitoylation by DHHC5 promotes phospholipid interactions that inhibit the Na pump
potentially relevant protein substrates of DHHC5
We demonstrated that LXR (show NR1H3 ELISA Kits) stimulation decreases mRNA and protein expression of FLOT2 (show FLOT2 ELISA Kits) and DHHC5 in MCF-7 cells. LXR (show NR1H3 ELISA Kits) stimulation also reduces Akt (show AKT1 ELISA Kits) phosphorylation and its localization at the plasma membrane
Data indicate that DHHC5 has oncogenic capacity and contributes to tumor formation in non-small cell lung cancer.
ZDHHC5 and SSTR5 (show SSTR5 ELISA Kits) are colocalized at the plasma membrane and coexpression of ZDHHC5 increased palmitoylation of SSTR5 (show SSTR5 ELISA Kits) whereas knock-down of endogenous ZDHHC5 by siRNAs decreased it.
Data show that palmitoyl acyltransferases DHHC5, DHHC6, and DHHC8 (show ZDHHC8 ELISA Kits) appear to be S-acylated on three cysteine residues within a novel CCX(7-13)C(S/T) motif downstream of a conserved Asp (show ASIP ELISA Kits)-His-His-Cys (show DNAJC5 ELISA Kits) cysteine-rich domain.
Palmitoyl acyltransferase for the G-protein coupled receptor SSTR5 and for FLOT2 (By similarity).
, palmitoyltransferase ZDHHC5
, probable palmitoyltransferase ZDHHC5
, zinc finger DHHC domain-containing protein 5
, membrane-associated DHHC5 zinc finger protein
, zinc finger protein 375
, zinc finger, DHHC domain containing 5