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ZFYVE22 encodes a protein that contains two WD domains and an FYVE zinc finger region. Additionally we are shipping Zinc Finger, FYVE Domain Containing 22 Antibodies (7) and many more products for this protein.
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Our results showed that WDFY2 inhibited cancer cell colony formation and migration via suppressing Akt (show AKT1 Proteins) pathway, making it a potential new therapeutic target in prostate cancer.
CDKN2D (show CDKN2D Proteins)-WDFY2 fusion could be an important molecular signature for understanding and classifying sub-lineages among heterogeneous high-grade serous ovarian carcinomas.
The ProF protein partially co-localizes with EEA1 on vesicular structures and binds to the protein kinases Akt and PKCzeta/lambda (protein kinase Czeta/lambda) via its WD-repeat propeller.
WDFY2, the WD40 and FYVE domain containing protein 2, has roles in endocytosis
presence of ProF increases the PKCzeta (show PRKCZ Proteins)-dependent phosphorylation of VAMP2 (show VAMP2 Proteins) in vitro
Data show that ProF binds to Foxo1 (show FOXO1 Proteins), a negative regulator of insulin (show INS Proteins) action and adipogenesis, and facilitates the phosphorylation and thus inactivation of Foxo1 (show FOXO1 Proteins) by Akt (show AKT1 Proteins).
This gene encodes a protein that contains two WD domains and an FYVE zinc finger region. The function of this gene is unknown. An alternatively spliced transcript variant of this gene may exist.
WD repeat and FYVE domain-containing protein 2
, WD40 and FYVE domain containing 2
, WD40- and FYVE domain-containing protein 2
, propeller-FYVE protein
, zinc finger FYVE domain-containing protein 22