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Zinc Finger, FYVE Domain Containing 26 (ZFYVE26) ELISA Kits

ZFYVE26 encodes a protein which contains a FYVE zinc finger binding domain. Additionally we are shipping Zinc Finger, FYVE Domain Containing 26 Antibodies (12) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human ZFYVE26 ZFYVE26 23503 Q68DK2
Anti-Mouse ZFYVE26 ZFYVE26 211978 Q5DU37
Anti-Rat ZFYVE26 ZFYVE26 314265 D4A8G9
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More ELISA Kits for Zinc Finger, FYVE Domain Containing 26 Interaction Partners

Zebrafish Zinc Finger, FYVE Domain Containing 26 (ZFYVE26) interaction partners

  1. we describe an uncharacterized cellular mechanism for Suf/Spastizin activity during secretion, which raises the possibility of novel therapeutic avenues for HSP research.

Human Zinc Finger, FYVE Domain Containing 26 (ZFYVE26) interaction partners

  1. spastizin and spatacsin (show SPG11 ELISA Kits) were essential components for the initiation of lysosomal tubulation. Together, these results link dysfunction of the autophagy/lysosomal biogenesis machinery to neurodegeneration.

  2. ZFYVE26 is a key determinant of autophagosome maturation

  3. spg15 should be search for in the case of juvenile levodopa reponsive parkinsonism

  4. We propose AP-5 (show AP5B1 ELISA Kits), SPG15, SPG11 (show SPG11 ELISA Kits) form a coat-like complex, with AP-5 (show AP5B1 ELISA Kits) involved in protein sorting, SPG15 facilitating docking of the coat onto membranes by interacting with PI3P via its FYVE domain, and SPG11 (show SPG11 ELISA Kits) (possibly together with SPG15) forming a scaffold.

  5. spastizin interacts with the autophagy related Beclin 1-UVRAG-Rubicon multiprotein complex and is required for autophagosome maturation.

  6. SPG15 was strongly expressed in cortical and spinal motor neurons and in embryos. It partially co-localized with multiple organelles, particularly with protein-trafficking vesicles, endoplasmic reticulum, microtubules and the mitochondria surface.

  7. Findings suggest a positive feedback loop for recruitment of FYVE-CENT and Beclin 1 (show BECN1 ELISA Kits) to the intercellular bridge during cytokinesis, and reveal a novel potential tumor suppressor mechanism for Beclin 1 (show BECN1 ELISA Kits).

  8. PtdIns(3)P production is essential for proper cytokinesis. PtdIns(3)P-binding centrosomal protein FYVE-CENT and TTC19 (show TTC19 ELISA Kits) control cytokinesis through their translocation from the centrosome to the midbody mediated by the kinesin protein KIF13A (show KIF13A ELISA Kits).

  9. phenotypic heterogeneity of SPG15 in which mental retardation or cognitive deterioration, but not all other signs of Kjellin syndrome, are associated with hereditary spastic paraplegia and significantly reduces the SPG15 locus

  10. Autosomal recessive HSP-TCC (show SFXN1 ELISA Kits) is a frequent subtype of complicated HSP in Tunisia and is clinically and genetically heterogeneous. SPG11 (show SPG11 ELISA Kits) and SPG15 are the major loci for this entity.

Mouse (Murine) Zinc Finger, FYVE Domain Containing 26 (ZFYVE26) interaction partners

  1. Increased levels of lysosomal enzymes in brains of aged knockout mice further support an alteration of the lysosomal compartment upon disruption of Zfyve26

Zinc Finger, FYVE Domain Containing 26 (ZFYVE26) Antigen Profile

Antigen Summary

This gene encodes a protein which contains a FYVE zinc finger binding domain. The presence of this domain is thought to target these proteins to membrane lipids through interaction with phospholipids in the membrane. Mutations in this gene are associated with autosomal recessive spastic paraplegia-15.

Gene names and symbols associated with ZFYVE26

  • zinc finger, FYVE domain containing 26 (zfyve26) antibody
  • zinc finger, FYVE domain containing 26 (ZFYVE26) antibody
  • zinc finger, FYVE domain containing 26 (LOC100353465) antibody
  • zinc finger, FYVE domain containing 26 (Zfyve26) antibody
  • 4930465A13 antibody
  • 9330197E15Rik antibody
  • A630028O16Rik antibody
  • FYVE-CENT antibody
  • Gm893 antibody
  • mKIAA0321 antibody
  • SPG15 antibody
  • wu:fc33a03 antibody

Protein level used designations for ZFYVE26

zspg15 , zinc finger, FYVE domain containing 26 , zinc finger FYVE domain-containing protein 26-like , FYVE domain-containing centrosomal protein , spastizin , zinc finger FYVE domain-containing protein 26

GENE ID SPECIES
324565 Danio rerio
423276 Gallus gallus
452989 Pan troglodytes
490745 Canis lupus familiaris
711274 Macaca mulatta
100155869 Sus scrofa
100353465 Oryctolagus cuniculus
100445888 Pongo abelii
100468320 Ailuropoda melanoleuca
100492179 Xenopus (Silurana) tropicalis
100557770 Anolis carolinensis
100591744 Nomascus leucogenys
23503 Homo sapiens
211978 Mus musculus
314265 Rattus norvegicus
514402 Bos taurus
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