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Zinc Finger, MYM-Type 2 (ZMYM2) ELISA Kits

The protein encoded by ZMYM2 is a zinc finger protein that may act as a transcription factor. Additionally we are shipping ZMYM2 Antibodies (41) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human ZMYM2 ZMYM2 7750 Q9UBW7
Anti-Mouse ZMYM2 ZMYM2 76007 Q9CU65
Anti-Rat ZMYM2 ZMYM2 305913  
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More ELISA Kits for ZMYM2 Interaction Partners

Human Zinc Finger, MYM-Type 2 (ZMYM2) interaction partners

  1. Multi-SUMO binding is mediated through multi-SIM (show SIM2 ELISA Kits) modules, and the functional importance of these interactions is demonstrated for the transcriptional corepressor ZMYM2/ZNF198

  2. downregulation of SUZ12 (show SUZ12 ELISA Kits) and ZNF198 leads to epigenetic reprogramming of infected hepatocytes. Because both Plk1 (show PLK1 ELISA Kits) and HOTAIR are elevated in many human cancers, we propose that their combined effects are involved in epigenetic reprogramming

  3. B-lymphoblastic leukemia/lymphoma associated with t(8;13)(p11 (show S100A10 ELISA Kits);q12)/ ZMYM2 (ZNF198)-FGFR1 (show FGFR1 ELISA Kits)

  4. We propose Plk1 (show PLK1 ELISA Kits) activity down-regulates ZNF198 and SUZ12 (show SUZ12 ELISA Kits), thereby enhancing both HBV replication and pX-mediated oncogenic transformation.

  5. cell transformation mediated by ZNF198-FGFR1 (show FGFR1 ELISA Kits) requires STAT5 (show STAT5A ELISA Kits) activation

  6. ZNF198/fibroblast growth factor receptor-1 (show FGFR1 ELISA Kits) has signaling function comparable with interleukin-6 (show IL6 ELISA Kits) cytokine receptors.

  7. SUMO-1 (show SUMO1 ELISA Kits), PML (show PML ELISA Kits) and ZNF198 colocalize to punctate structures, shown by immunocytochemistry to be PML (show PML ELISA Kits) bodies.

  8. ZNF198-FGFR1 (show FGFR1 ELISA Kits) activated both the AKT (show AKT1 ELISA Kits) and mitogen activated protein kinase (show MAPK1 ELISA Kits) (MAPK (show MAPK1 ELISA Kits)) prosurvival signaling pathways, resulting in elevated phosphorylation of the AKT (show AKT1 ELISA Kits) target FOXO3a (show FOXO3 ELISA Kits) at T32 and BAD at S112, respectively.

  9. HSPA1A (show HSPA1A ELISA Kits) is an important regulator of the stability and function of ZNF198 and its oncogenic derivative, ZNF198-FGFR1 (show FGFR1 ELISA Kits).

  10. ZNF198, through its multiple protein-protein interaction interfaces, helps to maintain the intact LSD1 (show KDM1A ELISA Kits)-CoREST (show RCOR1 ELISA Kits)-HDAC1 (show HDAC1 ELISA Kits) complex on specific, non-REST-responsive promoters and may also prevent SUMO-dependent dissociation of HDAC1 (show HDAC1 ELISA Kits)

Mouse (Murine) Zinc Finger, MYM-Type 2 (ZMYM2) interaction partners

  1. The study demonstrates frequent, constitutive activation of Notch1 (show NOTCH1 ELISA Kits) and its downstream target genes in T-cell lymphomas that arose in a murine model of Zmym2-Fgfr1 (show FGFR1 ELISA Kits) stem cell leukemia-lymphoma syndrome.

ZMYM2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a zinc finger protein that may act as a transcription factor. The encoded protein may be part of a BHC histone deacetylase complex. Translocation of this gene with the fibroblast growth factor receptor-1 gene (FGFR1) results in a fusion gene, which may be a cause of stem cell leukemia lymphoma syndrome (SCLL). Several transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with ZMYM2

  • zinc finger, MYM-type 2 (ZMYM2) antibody
  • zinc finger, MYM-type 2 (zmym2) antibody
  • zinc finger, MYM-type 2 (Zmym2) antibody
  • 5830413P05Rik antibody
  • fc07a10 antibody
  • FIM antibody
  • MGC83724 antibody
  • MYM antibody
  • RAMP antibody
  • SCLL antibody
  • si:dkey-51d17.6 antibody
  • wu:fc07a10 antibody
  • Zfp198 antibody
  • ZMYM2 antibody
  • Znf198 antibody

Protein level used designations for ZMYM2

zinc finger, MYM-type 2 , zinc finger protein 198 , fused in myeloproliferative disorders protein , rearranged in an atypical myeloproliferative disorder , zinc finger MYM-type protein 2 , MYM-type zinc finger protein 2

GENE ID SPECIES
452454 Pan troglodytes
570149 Danio rerio
721255 Macaca mulatta
100144668 Xenopus (Silurana) tropicalis
446388 Xenopus laevis
7750 Homo sapiens
76007 Mus musculus
418954 Gallus gallus
100174301 Pongo abelii
477346 Canis lupus familiaris
508731 Bos taurus
305913 Rattus norvegicus
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